Current Biology

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  1. The unstoppable march of the machines

    Current Biology 25(7) (2015)

    As robots are taking over more and more tasks formerly performed by human employees and algorithms backed up by big data covering our every move are beginning to shape how we experience our lives, it’s not just traditional concepts like privacy that are affected. The accelerating chang...
  2. Species, extinct before we know them?

    Current Biology 25(7):969 (2015)

  3. Howard Eichenbaum

    Current Biology 25(7) (2015)

    An interview with Howard Eichenbaum, who studies how memory is accomplished by brain circuits and systems.
  4. Autophagy: Starvation Relieves Transcriptional Repression of ATG Genes

    Current Biology 25(6):R238 (2015) PMID 25784045

    Autophagy is a highly regulated process about which relatively little is known, particularly concerning the transcriptional control of autophagy regulation. A new study identifies a key regulator of the expression of autophagy-related genes, thereby providing insights into the signalli...
  5. Can we avert marine mass extinctions?

    Current Biology 25(6):R209 (2015)

    The global spread of our species has led to a massive loss of terrestrial species, which dramatically changed the size distribution of land-based fauna and disrupted its ecological function. The less readily accessible ocean biotopes have so far been spared this fate, but lessons from ...
  6. Space in the brain

    Current Biology 25(6) (2015)

  7. Bacterial Actin and Tubulin Homologs in Cell Growth and Division

    Current Biology 25(6):R243 (2015)

    In contrast to the elaborate cytoskeletal machines harbored by eukaryotic cells, such as mitotic spindles, cytoskeletal structures detectable by typical negative stain electron microscopy are generally absent from bacterial cells. As a result, for decades it was thought that bacteria l...
  8. Coupled computations of three-dimensional shape and material

    Current Biology 25(6) (2015) PMID 25784037

    Retinal image structure arises from the interaction between a surface's three-dimensional shape, its reflectance and transmittance properties, and the surrounding light field. Any local image structure can be generated by an infinite number of different combinations of surface properties, which ...
  9. Uninflatable and Notch Control the Targeting of Sara Endosomes during Asymmetric Division

    Current Biology 25(6):817 (2015)

  10. Insect Navigation: Do Honeybees Learn to Follow Highways?

    Current Biology 25(6):R240 (2015) PMID 25784046

    Radar studies of a honeybee’s flights when it first leaves its nest suggest the features of the surrounding landscape that it learns guide future foraging trips.
  11. Rob Dunn

    Current Biology 25(6) (2015)

    Q&A with Rob Dunn, evolutionary biologist, ecologist and writer.
  12. Cyclin B3 Is a Mitotic Cyclin that Promotes the Metaphase-Anaphase Transition

    Current Biology 25(6):811 (2015) PMID 25754637

    The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkpoint (SAC), whose reversal upon chromosome alignment is thought to time anaphase [1–3], is functional during the rapid mitotic cycles of the Drosophila embryo; but its genetic inactivati...
  13. Rph1/KDM4 Mediates Nutrient-Limitation Signaling that Leads to the Transcriptional Induction of Autophagy

    Current Biology 25(5):546 (2015) PMID 25660547 PMCID PMC4348152

    Background Autophagy is a conserved process mediating vacuolar degradation and recycling. Autophagy is highly upregulated upon various stresses and is essential for cell survival in deleterious conditions. Autophagy defects are associated with severe pathologies, whereas unch...
  14. Drosophila Sugar Receptors in Sweet Taste Perception, Olfaction, and Internal Nutrient Sensing

    Current Biology 25(5):621 (2015) PMID 25702577

    Identification of nutritious compounds is dependent on expression of specific taste receptors in appropriate taste-cell types [1]. In contrast to mammals, which rely on a single, broadly tuned heterodimeric sugar receptor [2], the Drosophila genome harbors a small subfamily of eight, c...
  15. Distinct Organization and Regulation of the Outer Kinetochore KMN Network Downstream of CENP-C and CENP-T

    Current Biology 25(5):671 (2015) PMID 25660545 PMCID PMC4348146

    The kinetochore provides a vital connection between chromosomes and spindle microtubules [1, 2]. Defining the molecular architecture of the core kinetochore components is critical for understanding the mechanisms by which the kinetochore directs chromosome segregation. The KNL1/Mis12 c...
  16. Development of Connectivity in a Motoneuronal Network in Drosophila Larvae

    Current Biology 25(5):568 (2015) PMID 25702582 PMCID PMC4353686

    Background Much of our understanding of how neural networks develop is based on studies of sensory systems, revealing often highly stereotyped patterns of connections, particularly as these diverge from the presynaptic terminals of sensory neurons. We know considerably less a...
  17. A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor

    Current Biology 25(5):613 (2015) PMID 25660540

    Gall-forming arthropods are highly specialized herbivores that, in combination with their hosts, produce extended phenotypes with unique morphologies [1]. Many are economically important, and others have improved our understanding of ecology and adaptive radiation [2]. However, the mec...
  18. Ube3a Imprinting Impairs Circadian Robustness in Angelman Syndrome Models

    Current Biology 25(5):537 (2015) PMID 25660546 PMCID PMC4348236

    Background The paternal allele of Ube3a is silenced by imprinting in neurons, and Angelman syndrome (AS) is a disorder arising from a deletion or mutation of the maternal Ube3a allele, which thereby eliminates Ube3a neuronal expression. Sleep disorders such as short sleep dur...
  19. Multisensory Perception: Pinpointing Visual Enhancement by Appropriate Odors

    Current Biology 25(5):R196 (2015) PMID 25734268

    Multisensory contributions to perception are well studied, but their underlying brain mechanisms are poorly understood. A new study has exploited advances in fly optogenetics to pinpoint mechanisms that enhance responses to visual motion in the presence of ecologically relevant odors. ...
  20. Patrick Bateson

    Current Biology 25(5):R180 (2015)

    An interview with Patrick Bateson, retired ethologist with a particular interest in animal welfare.