Cell

Print ISSN
0092-8674
Electronic ISSN
1097-4172
Impact factor
32.406
Publisher
Sciencedirect
URL
http://www.sciencedirect.com/science/journal/00928674
Usage rank
12
Article count
16104
Free count
5542
Free percentage
0.344138
PDFs via platforms
Sciencedirect from 1974, Gale, Rcgp, CSA, Proquest, and Ingenta

  1. Ronald J. Konopka (1947–2015)

    Cell 161(2):187 (2015)

  2. In This Issue
    Author(s) unavailable

    Cell 161(2):177,179 (2015)

  3. How to Stop the Obesity Epidemic?
    Author(s) unavailable

    Cell 161(1):173 (2015)

  4. In This Issue
    Author(s) unavailable

    Cell 161(1) (2015)

    “Tell me what you eat, and I will tell what you are.” This quote, made famous by Brillat-Savarin in his seminal essay about gastronomy, summarizes the central role that food has played in the history of mankind. Food catalyzes reunion, celebration, and social identification. Conversely...
  5. Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

    Cell 160(5):842 (2015)

    Low energy states delay aging in multiple species, yet mechanisms coordinating energetics and longevity across tissues remain poorly defined. The conserved energy sensor AMP-activated protein kinase (AMPK) and its corresponding phosphatase calcineurin modulate longevity via the CREB re...
  6. Early Telomerase Inactivation Accelerates Aging Independently of Telomere Length

    Cell 160(5):928 (2015)

    Telomerase is required for long-term telomere maintenance and protection. Using single budding yeast mother cell analyses we found that, even early after telomerase inactivation (ETI), yeast mother cells show transient DNA damage response (DDR) episodes, stochastically altered cell-cyc...
  7. Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancers

    Cell 160(5):913 (2015)

    The breakage-fusion-bridge cycle is a classical mechanism of telomere-driven genome instability in which dysfunctional telomeres are fused to other chromosomal extremities, creating dicentric chromosomes that eventually break at mitosis. Here, we uncover a distinct pathway of telomere-...
  8. The Hunger Games

    Cell 160(5):805 (2015)

    Although AgRP and POMC neurons in the hypothalamus have long been associated with regulation of food intake, in this issue of Cell, Chen et al. use direct imaging in vivo to demonstrate rapid changes in their activity upon food presentation. The rapidity of their altered responses chal...
  9. Unfrozen
    Author(s) unavailable

    Cell 160(5):803 (2015)

  10. Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift Pathways

    Cell 160(5):870 (2015)

    Programmed ribosomal frameshifting produces alternative proteins from a single transcript. −1 frameshifting occurs on Escherichia coli’s dnaX mRNA containing a slippery sequence AAAAAAG and peripheral mRNA structural barriers. Here, we reveal hidden aspects of the frameshifting process...
  11. Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits

    Cell 160(5):829 (2015)

    Hunger is controlled by specialized neural circuits that translate homeostatic needs into motivated behaviors. These circuits are under chronic control by circulating signals of nutritional state, but their rapid dynamics on the timescale of behavior remain unknown. Here, we report opt...
  12. Unfrozen
    Author(s) unavailable

    Cell 160(5):803 (2015)

  13. Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancers

    Cell 160(5):913 (2015) PMID 25723166

    The breakage-fusion-bridge cycle is a classical mechanism of telomere-driven genome instability in which dysfunctional telomeres are fused to other chromosomal extremities, creating dicentric chromosomes that eventually break at mitosis. Here, we uncover a distinct pathway of telomere-...
  14. The Cellular and Molecular Basis of Direction Selectivity of Aδ-LTMRs

    Cell 160(5):1027 (2015)

  15. Fertile Waters for Aging Research

    Cell 160(5):814 (2015)

    The quest to slow aging has come far, and what used to be the domain of science fiction writers and snake oil salesmen may soon become science fact. Innovative new approaches, such as the use of the very short-lived African killifish (Harel et al.), are bridging the translational gap a...
  16. A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived Vertebrate

    Cell 160(5):1013 (2015)

    Aging is a complex process that affects multiple organs. Modeling aging and age-related diseases in the lab is challenging because classical vertebrate models have relatively long lifespans. Here, we develop the first platform for rapid exploration of age-dependent traits and diseases ...
  17. An Evolutionary Role for HIV Latency in Enhancing Viral Transmission

    Cell 160(5):1002 (2015)

    HIV latency is the chief obstacle to eradicating HIV but is widely believed to be an evolutionary accident providing no lentiviral fitness advantage. However, findings of latency being “hardwired” into HIV’s gene-regulatory circuitry appear inconsistent with latency being an evolutiona...
  18. ALT Telomeres Get Together with Nuclear Receptors

    Cell 160(5):811 (2015)

    Nuclear receptors bind chromosome ends in “alternative lengthening of telomeres” (ALT) cancer cells that maintain their ends by homologous recombination instead of telomerase. Marzec et al. now demonstrate that, in ALT cells, nuclear receptors not only trigger distal chromatin associat...
  19. Finding the Right Match Fast

    Cell 160(5):809 (2015)

    DNA recombinases face the daunting task of locating and pairing up specific sequences among millions of base pairs in a genome, all within about an hour. Qi et al. show that recombinases solve this problem by searching in 8-nt microhomology units, reducing the search space and accelera...
  20. In This Issue
    Author(s) unavailable

    Cell 160(5):799,801 (2015)