1. Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.

    Molecular Cell 59(2):188 (2015) PMID 26166704

    Enhancers instruct spatio-temporally specific gene expression in a manner tightly linked to higher-order chromatin architecture. Critical chromatin architectural regulators condensin I and condensin II play non-redundant roles controlling mitotic chromosomes. But the chromosomal locations of con...
  2. Eight Novel Capsular Polysaccharide Synthesis Gene Loci Identified in Nontypeable Streptococcus suis Isolates.

    Applied and Environmental Microbiology 81(12):4111 (2015) PMID 25862221

    Streptococcus suis is an important pathogen of pigs and may cause serious disease in humans. Serotyping is one of the important diagnostic tools and is used for the epidemiological study of S. suis. Nontypeable S. suis strains have been reported in many studies; however, the capsular polysacchar...
  3. Identification and characterization of Tu88, an antigenic gene from Theileria uilenbergi.

    Experimental Parasitology 153:63 (2015) PMID 25770598

    Theileria uilenbergi is a pathogen that causes ovine theileriosis. Prevention and control of theileriosis relies on its diagnosis at early stages of occurrence and requires understanding of proteins with antigenic properties from the pathogen. Despite its prevalence in China, only a few molecule...
  4. Comprehensive surveillance of the antibody response to Borrelia burgdorferi s.l. in small ruminants in China.

    Annals of Agricultural and Environmental Medicine 22(2):208 (2015) PMID 26094509

    Borrelia burgdorferi sensu lato, the etiological agent of Lyme disease, is tick transmitted and has a wide range of mammalian reservoirs in nature, including both wild and domestic animals. To understand the seroprevalence of B. burgdorferi s.l. in small ruminants will add value to the risk anal...
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  5. Report of Theileria luwenshuni and Theileria sp. RSR from cervids in Gansu, China.

    Parasitology Research 114(5):2023 (2015) PMID 25820647

    Theileria parasites are important tick-borne pathogens of animals and cause huge economic losses worldwide. Here, we undertook to assess the prevalence of Theileria spp. in cervids in Gansu, China, based on PCR analysis and sequencing of the 18S rRNA genes. Molecular survey showed that Theileria...
  6. Large-scale serological survey of bovine ephemeral fever in China

    Veterinary Microbiology 176(1-2):155 (2015)

    • We first developed the indirect ELISA kit for BEFV detection in the world. • We made first large-scale serological survey of BEFV from 1991 to present in China. ...
  7. Large-scale serological survey of bovine ephemeral fever in China.

    Veterinary Microbiology 176(1-2):155 (2015) PMID 25595266

    Bovine ephemeral fever (BEF) is caused by the arthropod-borne bovine ephemeral fever virus (BEFV), which is classified in the family Rhabdoviridae and the genus Ephemerovirus. A debilitating and sometimes fatal viral disease, BEF affects cattle and water buffalo. The epizootiology of BEF among c...
  8. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.

    PNAS 112(5):1380 (2015) PMID 25605944 PMCID PMC4321301

    Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation an...
  9. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.

    PNAS 112(5):1380 (2015) PMID 25605944

    Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation an...
  10. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.

    PNAS 112(5):1380 (2015) PMID 25605944 PMCID PMC4321301

    Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation an...
  11. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.

    PNAS 112(5):1380 (2015) PMID 25605944 PMCID PMC4321301

    Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation an...
  12. Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.

    PNAS 112(5):1380 (2015) PMID 25605944 PMCID PMC4321301

    Substantial evidence supports the hypothesis that enhancers are critical regulators of cell-type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation an...
  13. Does Haemaphysalis bispinosa (Acari: Ixodidae) really occur in China?

    Experimental and Applied Acarology 65(2):249 (2015) PMID 25304739

    Haemaphysalis bispinosa Neumann has been considered to exist in China, especially in the southern part of the country. However, H. bispinosa referred to in many Chinese research papers may in fact be H. longicornis, which is widely distributed in most regions of China. In order to clarify the oc...
  14. Does Haemaphysalis bispinosa (Acari: Ixodidae) really occur in China?

    Experimental and Applied Acarology 65(2):249 (2015) PMID 25304739

    Haemaphysalis bispinosa Neumann has been considered to exist in China, especially in the southern part of the country. However, H. bispinosa referred to in many Chinese research papers may in fact be H. longicornis, which is widely distributed in most regions of China. In order to clarify the oc...
  15. Does Haemaphysalis bispinosa (Acari: Ixodidae) really occur in China?

    Experimental and Applied Acarology 65(2):249 (2015) PMID 25304739

    Haemaphysalis bispinosa Neumann has been considered to exist in China, especially in the southern part of the country. However, H. bispinosa referred to in many Chinese research papers may in fact be H. longicornis, which is widely distributed in most regions of China. In order to clarify the oc...
  16. Ligand-dependent enhancer activation regulated by topoisomerase-I activity.

    Cell 160(3):367 (2015) PMID 25619691

    The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicking to relieve torsional stre...
  17. Ligand-dependent enhancer activation regulated by topoisomerase-I activity.

    Cell 160(3):367 (2015) PMID 25619691

    The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicking to relieve torsional stre...
  18. Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity

    Cell 160(3):367 (2015) PMID 25619691

    The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicking to relieve tors...
  19. Ligand-dependent enhancer activation regulated by topoisomerase-I activity.

    Cell 160(3):367 (2015) PMID 25619691

    The discovery that enhancers are regulated transcription units, encoding eRNAs, has raised new questions about the mechanisms of their activation. Here, we report an unexpected molecular mechanism that underlies ligand-dependent enhancer activation, based on DNA nicking to relieve torsional stre...
  20. CeCaFDB: a curated database for the documentation, visualization and comparative analysis of central carbon metabolic flux distributions explored by 13C-fluxomics.

    Nucleic Acids Research 43(Database issue):D549 (2015) PMID 25392417

    The Central Carbon Metabolic Flux Database (CeCaFDB, available at http://www.cecafdb.org) is a manually curated, multipurpose and open-access database for the documentation, visualization and comparative analysis of the quantitative flux results of central carbon metabolism among microbes and an...
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