1. Assessing the Applicability of FISH-based Prematurely Condensed Dicentric Chromosome Assay in Triage Biodosimetry.

    Health Physics 108(3):371 (2015) PMID 25627950

    The dicentric chromosome assay (DCA) has been regarded as the gold standard of radiation biodosimetry. The assay, however, requires a 2-d peripheral blood lymphocyte culture before starting metaphase chromosome analyses to estimate biological doses. Other biological assays also have drawbacks wi...
  2. Assessing the applicability of FISH-based prematurely condensed dicentric chromosome assay in triage biodosimetry.

    Health Physics 108(3):371 (2015) PMID 25627950

    The dicentric chromosome assay (DCA) has been regarded as the gold standard of radiation biodosimetry. The assay, however, requires a 2-d peripheral blood lymphocyte culture before starting metaphase chromosome analyses to estimate biological doses. Other biological assays also have drawbacks wi...
  3. A Bayesian hierarchical method to account for random effects in cytogenetic dosimetry based on calibration curves.

    Radiation and Environmental Biophysics 53(4):775 (2014) PMID 25156016

    The dicentric chromosome assay (DCA) is one of the most sensitive and reliable methods of inferring doses of radiation exposure in patients. In DCA, one calibration curve is prepared in advance by in vitro irradiation to blood samples from one or sometimes multiple healthy donors in considering ...
  4. A Bayesian hierarchical method to account for random effects in cytogenetic dosimetry based on calibration curves.

    Radiation and Environmental Biophysics 53(4):775 (2014) PMID 25156016

    The dicentric chromosome assay (DCA) is one of the most sensitive and reliable methods of inferring doses of radiation exposure in patients. In DCA, one calibration curve is prepared in advance by in vitro irradiation to blood samples from one or sometimes multiple healthy donors in considering ...
  5. Biodosimetry of restoration workers for the Tokyo Electric Power Company (TEPCO) Fukushima Daiichi nuclear power station accident.

    Health Physics 105(4):366 (2013) PMID 23982613

    The biological dose of nuclear workers engaged in emergency response tasks at Tokyo Electric Power Company (TEPCO) Fukushima Daiichi Nuclear Power Station was estimated in the present study. As the national core center for radiation emergency medical preparedness in Japan, the National Institute...
  6. Biodosimetry of restoration workers for the Tokyo Electric Power Company (TEPCO) Fukushima Daiichi nuclear power station accident.

    Health Physics 105(4):366 (2013) PMID 23982613

    The biological dose of nuclear workers engaged in emergency response tasks at Tokyo Electric Power Company (TEPCO) Fukushima Daiichi Nuclear Power Station was estimated in the present study. As the national core center for radiation emergency medical preparedness in Japan, the National Institute...
  7. The history of human populations in the Japanese Archipelago inferred from genome-wide SNP data with a special reference to the Ainu and the Ryukyuan populations.

    Journal of Human Genetics 57(12):787 (2012) PMID 23135232

    The Japanese Archipelago stretches over 4000 km from north to south, and is the homeland of the three human populations; the Ainu, the Mainland Japanese and the Ryukyuan. The archeological evidence of human residence on this Archipelago goes back to >30 000 years, and various migration routes an...
  8. The history of human populations in the Japanese Archipelago inferred from genome-wide SNP data with a special reference to the Ainu and the Ryukyuan populations.

    Journal of Human Genetics 57(12):787 (2012) PMID 23135232

    The Japanese Archipelago stretches over 4000 km from north to south, and is the homeland of the three human populations; the Ainu, the Mainland Japanese and the Ryukyuan. The archeological evidence of human residence on this Archipelago goes back to >30 000 years, and various migration routes an...
  9. Estrogen-like activity and dual roles in cell signaling of anAgaricus blazeiMurrill mycelia-dikaryon extract

    Microbiological Research 167(4):231 (2012) PMID 22015258

    Agaricus blazei (A. blazei) Murrill mycelia-dikaryon has attracted the attention of scientists and clinicians worldwide owing to its potential for the treatment of cancer. However, little is known about its effect on other pathologies. This study sought to extend the potential medical ...
  10. Estrogen-like activity and dual roles in cell signaling of an Agaricus blazei Murrill mycelia-dikaryon extract.

    Microbiological Research 167(4):231 (2012) PMID 22015258

    Agaricus blazei (A. blazei) Murrill mycelia-dikaryon has attracted the attention of scientists and clinicians worldwide owing to its potential for the treatment of cancer. However, little is known about its effect on other pathologies. This study sought to extend the potential medical usefulness...
  11. Estrogen-like activity and dual roles in cell signaling of anAgaricus blazeiMurrill mycelia-dikaryon extract

    Microbiological Research 167(4):231 (2012)

    Agaricus blazei (A. blazei) Murrill mycelia-dikaryon has attracted the attention of scientists and clinicians worldwide owing to its potential for the treatment of cancer. However, little is known about its effect on other pathologies. This study sought to extend the potential medical ...
  12. Estrogen-like activity and dual roles in cell signaling of an Agaricus blazei Murrill mycelia-dikaryon extract.

    Microbiological Research 167(4):231 (2012) PMID 22015258

    Agaricus blazei (A. blazei) Murrill mycelia-dikaryon has attracted the attention of scientists and clinicians worldwide owing to its potential for the treatment of cancer. However, little is known about its effect on other pathologies. This study sought to extend the potential medical usefulness...
  13. Estrogen-like activity and dual roles in cell signaling of an Agaricus blazei Murrill mycelia-dikaryon extract.

    Microbiological Research 167(4):231 (2012) PMID 22015258

    Agaricus blazei (A. blazei) Murrill mycelia-dikaryon has attracted the attention of scientists and clinicians worldwide owing to its potential for the treatment of cancer. However, little is known about its effect on other pathologies. This study sought to extend the potential medical usefulness...
  14. Microarray CGH analyses of chromosomal 20q deletions in patients with hematopoietic malignancies

    Cancer Genetics 205(1-2):18 (2012)

    The chromosomal abnormality del(20q) is mostly found in various myeloid disorders, including myelodysplastic syndromes, myeloproliferative neoplasms, and acute myeloid leukemia. Here, microarray comparative genomic hybridization (aCGH) analyses of 14 patients cytogenetically confirmed ...
  15. Microarray CGH analyses of chromosomal 20q deletions in patients with hematopoietic malignancies

    Cancer Genetics 205(1-2):18 (2012) PMID 22429594

    The chromosomal abnormality del(20q) is mostly found in various myeloid disorders, including myelodysplastic syndromes, myeloproliferative neoplasms, and acute myeloid leukemia. Here, microarray comparative genomic hybridization (aCGH) analyses of 14 patients cytogenetically confirmed ...
  16. Microarray CGH analyses of chromosomal 20q deletions in patients with hematopoietic malignancies.

    Cancer Genetics 205(1-2):18 (2012) PMID 22429594

    The chromosomal abnormality del(20q) is mostly found in various myeloid disorders, including myelodysplastic syndromes, myeloproliferative neoplasms, and acute myeloid leukemia. Here, microarray comparative genomic hybridization (aCGH) analyses of 14 patients cytogenetically confirmed to carry t...
  17. Development of an integrative database with 499 novel microsatellite markers for Macaca fascicularis.

    BMC Genetics 10:24 (2009) PMID 19497132 PMCID PMC2702342

    Cynomolgus macaques (Macaca fascicularis) are a valuable resource for linkage studies of genetic disorders, but their microsatellite markers are not sufficient. In genetic studies, a prerequisite for mapping genes is development of a genome-wide set of microsatellite markers in target organisms....
  18. Development of an integrative database with 499 novel microsatellite markers for Macaca fascicularis.

    BMC Genetics 10:24 (2009) PMID 19497132 PMCID PMC2702342

    Cynomolgus macaques (Macaca fascicularis) are a valuable resource for linkage studies of genetic disorders, but their microsatellite markers are not sufficient. In genetic studies, a prerequisite for mapping genes is development of a genome-wide set of microsatellite markers in target organisms....
  19. Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome.

    Gene 399(1):1 (2007) PMID 17574350

    The genetic basis of the phenotypic difference between human and chimpanzee is one of the most actively pursued issues in current genomics. Although the genomic divergence between the two species has been described, the transcriptomic divergence has not been well documented. Thus, we newly seque...
  20. Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome

    Gene 399(1):1 (2007) PMID 17574350

    The genetic basis of the phenotypic difference between human and chimpanzee is one of the most actively pursued issues in current genomics. Although the genomic divergence between the two species has been described, the transcriptomic divergence has not been well documented. Thus, we newly ...