1. AtPEPTIDE RECEPTOR2 mediates the AtPEPTIDE1-induced cytosolic Ca(2+) rise, which is required for the suppression of Glutamine Dumper gene expression in Arabidopsis roots.

    Journal of Integrative Plant Biology 56(7):684 (2014) PMID 24450616

    AtPEPTIDE RECEPTOR2 (AtPEPR2) is a member of leucine-rich repeat receptor-like kinase family and binds to a group of AtPROPEP gene-encoded endogenous peptides, AtPeps. Previously, we found that AtPEPR2 plays a moderate role in the AtPep1-mediated innate immunity responses in Arabidopsis leaf. In...
  2. AtPEPTIDE RECEPTOR2 mediates the AtPEPTIDE1-induced cytosolic Ca(2+) rise, which is required for the suppression of Glutamine Dumper gene expression in Arabidopsis roots.

    Journal of Integrative Plant Biology 56(7):684 (2014) PMID 24450616

    AtPEPTIDE RECEPTOR2 (AtPEPR2) is a member of leucine-rich repeat receptor-like kinase family and binds to a group of AtPROPEP gene-encoded endogenous peptides, AtPeps. Previously, we found that AtPEPR2 plays a moderate role in the AtPep1-mediated innate immunity responses in Arabidopsis leaf. In...
  3. AtPEPTIDE RECEPTOR2 mediates the AtPEPTIDE1-induced cytosolic Ca(2+) rise, which is required for the suppression of Glutamine Dumper gene expression in Arabidopsis roots.

    Journal of Integrative Plant Biology 56(7):684 (2014) PMID 24450616

    AtPEPTIDE RECEPTOR2 (AtPEPR2) is a member of leucine-rich repeat receptor-like kinase family and binds to a group of AtPROPEP gene-encoded endogenous peptides, AtPeps. Previously, we found that AtPEPR2 plays a moderate role in the AtPep1-mediated innate immunity responses in Arabidopsis leaf. In...
  4. Endogenous peptide elicitors in higher plants.

    Current Opinion in Plant Biology 14(4):351 (2011) PMID 21636314

    Plant defense responses against invading organisms are initiated through the perception of molecules associated with attacking microbes and herbivores by pattern recognition receptors. In addition to elicitor molecules derived from attacking organisms, plants recognize host-derived molecules. Th...
  5. Endogenous peptide elicitors in higher plants.

    Current Opinion in Plant Biology 14(4):351 (2011) PMID 21636314

    Plant defense responses against invading organisms are initiated through the perception of molecules associated with attacking microbes and herbivores by pattern recognition receptors. In addition to elicitor molecules derived from attacking organisms, plants recognize host-derived molecules. Th...
  6. Endogenous peptide elicitors in higher plants.

    Current Opinion in Plant Biology 14(4):351 (2011) PMID 21636314

    Plant defense responses against invading organisms are initiated through the perception of molecules associated with attacking microbes and herbivores by pattern recognition receptors. In addition to elicitor molecules derived from attacking organisms, plants recognize host-derived molecules. Th...
  7. GmPep914, an eight-amino acid peptide isolated from soybean leaves, activates defense-related genes.

    Plant Physiology 156(2):932 (2011) PMID 21478368 PMCID PMC3177287

    Only a handful of endogenous peptide defense signals have been isolated from plants. Herein, we report a novel peptide from soybean (Glycine max) leaves that is capable of alkalinizing the media of soybean suspension cells, a response that is generally associated with defense peptides. The pepti...
  8. GmPep914, an eight-amino acid peptide isolated from soybean leaves, activates defense-related genes.

    Plant Physiology 156(2):932 (2011) PMID 21478368 PMCID PMC3177287

    Only a handful of endogenous peptide defense signals have been isolated from plants. Herein, we report a novel peptide from soybean (Glycine max) leaves that is capable of alkalinizing the media of soybean suspension cells, a response that is generally associated with defense peptides. The pepti...
  9. Endogenous peptide elicitors in higher plants

    Current Opinion in Plant Biology 14(4):351 (2011) PMID 21636314

    Highlights ► Host-derived molecules called endogenous elicitors induce and amplify defense responses in higher plants. ► Five families of endogenous peptide elicitors have been found thus far. ► The endogenous peptide elicitors share downstream signaling mechanisms with microbe-associa...
  10. Endogenous peptide elicitors in higher plants

    Current Opinion in Plant Biology 14(4):351 (2011)

    Highlights ► Host-derived molecules called endogenous elicitors induce and amplify defense responses in higher plants. ► Five families of endogenous peptide elicitors have been found thus far. ► The endogenous peptide elicitors share downstream signaling mechanisms with microbe-associa...
  11. Ca2+ signaling by plant Arabidopsis thaliana Pep peptides depends on AtPepR1, a receptor with guanylyl cyclase activity, and cGMP-activated Ca2+ channels.

    PNAS 107(49):21193 (2010) PMID 21088220 PMCID PMC3000296

    A family of peptide signaling molecules (AtPeps) and their plasma membrane receptor AtPepR1 are known to act in pathogen-defense signaling cascades in plants. Little is currently known about the molecular mechanisms that link these signaling peptides and their receptor, a leucine-rich repeat rec...
  12. Ca2+ signaling by plant Arabidopsis thaliana Pep peptides depends on AtPepR1, a receptor with guanylyl cyclase activity, and cGMP-activated Ca2+ channels.

    PNAS 107(49):21193 (2010) PMID 21088220 PMCID PMC3000296

    A family of peptide signaling molecules (AtPeps) and their plasma membrane receptor AtPepR1 are known to act in pathogen-defense signaling cascades in plants. Little is currently known about the molecular mechanisms that link these signaling peptides and their receptor, a leucine-rich repeat rec...
  13. Structure-activity studies of GmSubPep, a soybean peptide defense signal derived from an extracellular protease.

    Peptides 31(12):2159 (2010) PMID 20833217

    GmSubPep, a 12-amino acid peptide isolated from soybean leaves, induces the expression of genes in soybean suspension-cultured cells that encode proteins involved in defense against pathogens. The peptide is derived from an extracellular subtilisin-like protease (subtilase) and binds a putative ...
  14. Structure-activity studies of RALF, Rapid Alkalinization Factor, reveal an essential--YISY--motif.

    Peptides 31(11):1973 (2010) PMID 20800638

    Rapid Alkalinization Factor (RALF) is a 49-amino acid peptide initially isolated from tobacco leaves that is capable of arresting both root and pollen tube growth. With suspension cells, addition of RALF causes an elevation of the pH of the extracellular media, caused by the blockage of a proton...
  15. Structure-activity studies of RALF, Rapid Alkalinization Factor, reveal an essential--YISY--motif.

    Peptides 31(11):1973 (2010) PMID 20800638

    Rapid Alkalinization Factor (RALF) is a 49-amino acid peptide initially isolated from tobacco leaves that is capable of arresting both root and pollen tube growth. With suspension cells, addition of RALF causes an elevation of the pH of the extracellular media, caused by the blockage of a proton...
  16. A subtilisin-like protein from soybean contains an embedded, cryptic signal that activates defense-related genes.

    PNAS 107(33):14921 (2010) PMID 20679205 PMCID PMC2930467

    Among the arsenal of plant-derived compounds activated upon attack by herbivores and pathogens are small peptides that initiate and amplify defense responses. However, only a handful of plant signaling peptides have been reported. Here, we have isolated a 12-aa peptide from soybean (Glycine max)...
  17. A subtilisin-like protein from soybean contains an embedded, cryptic signal that activates defense-related genes.

    PNAS 107(33):14921 (2010) PMID 20679205 PMCID PMC2930467

    Among the arsenal of plant-derived compounds activated upon attack by herbivores and pathogens are small peptides that initiate and amplify defense responses. However, only a handful of plant signaling peptides have been reported. Here, we have isolated a 12-aa peptide from soybean (Glycine max)...
  18. PEPR2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis.

    Plant Cell 22(2):508 (2010) PMID 20179141 PMCID PMC2845411

    Pep1 is a 23-amino acid peptide that enhances resistance to a root pathogen, Pythium irregulare. Pep1 and its homologs (Pep2 to Pep7) are endogenous amplifiers of innate immunity of Arabidopsis thaliana that induce the transcription of defense-related genes and bind to PEPR1, a plasma membrane l...
  19. PEPR2 is a second receptor for the Pep1 and Pep2 peptides and contributes to defense responses in Arabidopsis.

    Plant Cell 22(2):508 (2010) PMID 20179141 PMCID PMC2845411

    Pep1 is a 23-amino acid peptide that enhances resistance to a root pathogen, Pythium irregulare. Pep1 and its homologs (Pep2 to Pep7) are endogenous amplifiers of innate immunity of Arabidopsis thaliana that induce the transcription of defense-related genes and bind to PEPR1, a plasma membrane l...
  20. Structure–activity studies of GmSubPep, a soybean peptide defense signal derived from an extracellular protease

    Peptides 31(12):2159 (2010)

    Research highlights ▶ Substitutions of alanine at each of the 12 amino acid positions revealed that the amino acids at positions 10 (arginine) and 12 (histidine) were essential for activity. ▶ Both analogs, [A 10]GmSubPep and [A 12]GmSubPep were able to reduce the physiolog...