1. Assessment of chlorpyrifos exposure and absorbed daily doses among infants living in an agricultural area of the Province of Jiangsu, China.

    International Archives of Occupational and Envi... 87(7):753 (2014) PMID 24257932

    Chlorpyrifos (CPF) is one of the most widely used organophosphorous pesticides in China. However, few reports on CPF pesticide exposure and body burden of infants at 2 years of age in China are available. The aim of this study was to assess the exposure level and the absorbed daily dose (ADD) of...
  2. Reversal of hepatocyte senescence after continuous in vivo cell proliferation.

    Hepatology 60(1):349 (2014) PMID 24711261

    A better understanding of hepatocyte senescence could be used to treat age-dependent disease processes of the liver. Whether continuously proliferating hepatocytes could avoid or reverse senescence has not yet been fully elucidated. We confirmed that the livers of aged mice accumulated senescent...
  3. [Paraquat involves differentiation of human neural stem cells via Notch signaling].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 31(7):492 (2013) PMID 24053911

    To investigate effects of paraquat on the mRNA expression of key elements of Notch signaling (Notch1, Jagged1 and DTX1) during differentiation process of human neural stem cells (hNSCs). hNSCs exposed to PQ at the concentrations 0.10, 1.00, 10.00 M. Cell proliferation ability was assessed using ...
  4. [The protective effect of DR2 activation on hypoxia/reperfusion injury in the neonatal rat cardiomyocytes and related mechanism].

    Zhongguo ying yong sheng li xue za zhi = Zhongg... 29(4):289 (2013) PMID 24175544

    To observe the effect of dopamine receptor (DR2) activation on hypoxia/reperfusion injury (HRI) in the neonatal rat cardiomyocytes, and to explore its mechanism. The hypoxia/reperfusion (H/R) injury model was established in primarily cultured neonatal rat cardiomyocytes, and randomly assigned: c...
  5. [Determination of1-bromopropane in the workplace air by GC-FID].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 31(6):467 (2013) PMID 23803550

    To establish a method for determination 1-bromopropane (1-BP) in workplace air by gas chromatography-flame ionization detector (GC-FID). 1-bromopropane in workplace air was collected with activated charcoal tube, then desorbed by carbon disulfide and determined by GC-FID. 1-bromopropane was quan...
  6. [Effects of pyrrolidine dithiocarbamate on expressions of α-smooth muscle actin, integrin α5 and fibronectin in acute paraquat poisoned rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 31(5):341 (2013) PMID 23803522

    To observe the expressions of α-SMA, integrin α5 and fibronectin (Fn) in acute paraquat poisoned rats and the effect of PDTC. To investigate the mechanism of paraquat-induced pulmonary fibrosis. Sprague-Dawley rats were randomly divided into three experimental groups: Control group (6 rats), PQ ...
  7. [Intervention of pyrrolidine dithiocarbamate on expressions of connective tissue growth factor, type I collagen, and type III collage in acute paraquat poisoned rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 31(1):4 (2013) PMID 23433149

    To observe the changes in the expression of connective tissue growth factor (CTGF), type I collagen (Col I), and type III collagen (Col III) among the rats with acute paraquat (PQ) poisoning and the intervention effect of pyrrolidine dithiocarbamate (PDTC) on their expression, and to investigate...
  8. Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis.

    The Journal of Pain 12(9):974 (2011) PMID 21680256

    Although electroacupuncture (EA) has been proven to effectively relieve pain associated with arthritis, the underlying mechanism of EA analgesia requires further investigation. Here, the involvement of spinal neurotrophin-3 (NT-3) in EA's analgesic effects on complete Freund's adjuvant (CFA)-ind...
  9. [Involvement of excitatory amino acid system in astrocytes activation caused by dimethoate].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 29(4):260 (2011) PMID 21941777

    To study the involvement of excitatory amino acid system in astrocytes activation caused by dimethoate. Pure-cultured astrocytes were gained by three passages from primary cultured rat nerve cells, then treated with 10(-6),10(-5),10(-4) mol/L dimethoate for 48 h, 50 micromol/L and 100 micromol/L...
  10. Involvement of Spinal Neurotrophin-3 in Electroacupuncture Analgesia and Inhibition of Spinal Glial Activation in Rat Model of Monoarthritis

    The Journal of Pain 12(9):974 (2011)

    Although electroacupuncture (EA) has been proven to effectively relieve pain associated with arthritis, the underlying mechanism of EA analgesia requires further investigation. Here, the involvement of spinal neurotrophin-3 (NT-3) in EA’s analgesic effects on complete Freund’s adjuvant (CFA...
  11. [Role of connective tissue growth factor and α-smooth muscle actin in pulmonary fibrosis among acute paraquat poisoned rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 28(10):729 (2010) PMID 21126421

    to observe the expression of the connective tissue growth (CTGF) and a smooth muscle actin (α-SMA) in acute paraquat (PQ) poisoned rats and investigate the mechanism of paraquat-induced pulmonary fibrosis. sprague-Dawley rats were randomly divided into two experimental groups: control group (6 r...
  12. [Effects of controlling specific dangerous pesticides on prevention of acute pesticide poisoning in rural area].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 28(9):641 (2010) PMID 21126472

    To investigate the effects of controlling the specific dangerous pesticides on prevention of acute pesticide poisoning in rural area. The data of reported cases of pesticide poisoning were analyzed to find out the specific dangerous pesticide in acute pesticide poisoning. Then the occurrence of ...
  13. [Toxic effect of neonatal exposure to 2,2',4,4',5,5'-hexa-chlorobiphenyl on spermatogenesis in rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 28(7):512 (2010) PMID 21114030

    To determine the long-term testicular effect after neonatal exposure to 2,2', 4,4',5,5'-hexa-chlorobiphenyl (PCB153). On birth day (Postnatal day 0, PNDO), the Sprague-Dawley (SD) male rats were mixed together and divided into 12 pups/litter. At PND1, the rats were grouped randomly into control ...
  14. [Risk assessment of nerve conduction velocity in workers exposed to lead].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 28(3):164 (2010) PMID 20635686

    To explore the dose-effect relationship between lead exposure and nerve conduction velocity, and to assess risk characteristics of nerve conduction velocity induced by lead exposure. The external dose, internal dose (blood lead, urine lead) and the conduction velocity of peripheral nerve were ex...
  15. [Risk assessment of renal dysfunction caused by occupational lead exposure].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 28(3):170 (2010) PMID 20635687

    To assess the risk of renal dysfunction caused by occupational lead exposure through epidemiological investigation. The workers in a battery factory were selected as the subjects for the exposure and effect assessment. The occupational environmental monitoring data was collected and used to calc...
  16. [Effect of neonatal exposure to environmental pollutants on the DNA methylation of rat testis].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 27(11):649 (2009) PMID 20137407

    To investigate the effects of neonatal exposure of DNA methylation inhibitor, Cadmium and PCB153 on DNA methylation, apoptosis and spermatogenesis in SD rats. Neonatal SD rats were randomly divided into 10 groups and received oral administrations of PCB153 (0.025, 0. 250, 2.500 mg/kg), or Cadmiu...
  17. [Changes of cytokine and nuclear factor-kappa B in acute paraquat poisoned rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 27(8):463 (2009) PMID 20095326

    To observe the changes of cytokine and NF-kappaB activity in acute paraquat poisoned rats and the effect of PDTC and the mechanism of lung injury caused by paraquat poisoning. Sprague-Dawley (SD) rats were randomly divided into three groups: Control group (6 rats), PQ group (56 rats) and PQ + PD...
  18. [Change of oxidative stress and nuclear factor-kappa B in acute paraquat poisoned rats].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 27(8):457 (2009) PMID 20095325

    To investigate the change of oxidative stress and nuclear factor-kappaB (NF-kappaB) activity in acute paraquat (PQ) poisoned rats and the effect of PDTC. 144 SD rats were randomly divided into four experimental groups: control group (6 rats), PDTC group (36 rats), PQ group (56 rats) and PQ + PDT...
  19. [Effect of dimethoate on primary cultured rat cortical neuron].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 27(4):198 (2009) PMID 19493481

    To investigate the effect and mechanisms of dimethoate on the primary cultured cortical neuronal cell injury. Cortical neuronal cells were isolated and cultured in serum free medium for 6 days in vitro, and 1, 5, 10, 50 and 100 micromol/L dimethoate were added to the medium and intracellular SOD...
  20. {N'-[(E)-(5-Bromo-2-oxidophen-yl)(phen-yl)methyl-ene]benzohydrazidato}pyridine-copper(II).

    Acta Crystallographica Section E 65(Pt 9):m1047 (2009) PMID 21577408 PMCID PMC2970041

    The asymmetric unit of title complex, [Cu(C(20)H(13)BrN(2)O(2))(C(5)H(5)N)], contains two independent mol-ecules. In each mol-ecule, the central Cu(II) atom has a square-planar environment formed by the tridentate hydrazone and the monodentate pyridine ligands, with the N atoms in a trans arrang...