1. A pulse-chase strategy for EdU labelling assay is able to rapidly quantify cell division orientation.

    New Phytologist 211(4):1462 (2016) PMID 27121010

    Measurement of the direction of cell division is an important, yet difficult, task to analyse how a plant organ acquires its final shape from an initially small group of cells. We introduce a method that rapidly and easily quantifies cell division direction and is applicable to all plant species...
  2. Expression of nuclear factor, erythroid 2-like 2-mediated genes differentiates tuberculosis.

    Tuberculosis 99:56 (2016) PMID 27450006

    During infection and host defense, nuclear factor, erythroid 2-like 2 (Nrf2) dependent signaling is an efficient antioxidant defensive mechanism used by host cells to control the destructive effects of reactive oxygen species. This allows for effective defense responses against microbes while mi...
  3. In vivo injection of α-bungarotoxin to improve the efficiency of motor endplate labeling.

    Brain and Behavior 6(6):e00468 (2016) PMID 27186443 PMCID PMC4851864

    Motor endplates are composed of a motor neuron terminal and muscle fiber and are distributed in skeletal muscle, causing muscle contraction. However, traditional motor endplate staining methods are limited to the observation of partial skeletal muscle. The procedure was time-consuming due to str...
  4. Collateral development and spinal motor reorganization after nerve injury and repair.

    American journal of translational research 8(7):2897 (2016) PMID 27508011 PMCID PMC4969427

    Functional recovery is often unsatisfactory after severe extended nerve defects or proximal nerve trunks injuries repaired by traditional repair methods, as the long regeneration distance for the regenerated axons to reinnervate their original target end-organs. The proximal nerve stump can rege...
  5. Peripheral nerve mutilation through biodegradable conduit small gap tubulisation: a multicentre randomised trial

    The Lancet 386:S40 (2015)

    Background Although peripheral nerve injury is repaired by ingenious epineurial neurorrhaphy, functional recovery is usually not satisfactory and is hindered by many factors, including the misconnections of sensory and motor nerve fibres, difficulties in target organ reinnerv...
  6. Changes and trends of pre-hospital emergency disease spectrum in Beijing in 2003–12: a retrospective study

    The Lancet 386:S39 (2015)

    Background Pre-hospital emergency call is a crucial indicator of emergency disease spectrum. Since Beijing has changed substantially in economy and population, analysis of the trend of the emergency disease spectrum can greatly contribute to pre-hospital emergency planning. ...
  7. Current state of trauma care in China, tools to predict death and ICU admission after arrival to hospital.

    Injury 46(9):1784 (2015) PMID 26093963

    In China, a nationwide emergency system takes charge of pre-hospital emergency services, and it adopts a proximity principle to send trauma patients to the nearest hospitals. However, many severely injured patients have been sent to low level hospitals with no capability to treat severe trauma. ...
  8. Road traffic injury and rescue system in China.

    The Lancet 385(9978):1622 (2015) PMID 25943819

  9. Early nerve protection with anterior interosseous nerve in modified end-to-side neurorrhaphy repairs high ulnar nerve injury: a hypothesis of a novel surgical technique.

    Artificial Cells, Nanomedicine and Biotechnology 43(2):103 (2015) PMID 24195580

    High ulnar nerve injuries frequently result in poor functional recovery. The prolonged denervation of target muscle largely accounts for the poor functional outcome. There are no approved effective treatments for high ulnar nerve injuries. However, the technique of reverse end-to-side (RETS) off...
  10. Motor function recovery during peripheral nerve multiple regeneration.

    Journal Of Tissue Engineering And Regenerative ... 9(4):415 (2015) PMID 24323657

    Neuronal functional compensation and multiple regenerating axon sprouting occur during peripheral nerve regeneration. Sprouting nerve buds were quantitatively maintained and had matured when multiple injured distal nerves were anastomosed to smaller number of proximal nerve stumps; this has posi...
  11. Specificity of motor axon regeneration: a comparison of recovery following biodegradable conduit small gap tubulization and epineurial neurorrhaphy.

    American journal of translational research 7(1):53 (2015) PMID 25755828 PMCID PMC4346523

    Functional recovery is often unsatisfactory after lesions in the peripheral nervous system despite the strong potential for regeneration and advances in microsurgical techniques. Axonal regeneration in mixed nerve into inappropriate pathways is a major contributing factor to this failure. In thi...
  12. Preconditioning with glycyrrhizic, ferulic, paeoniflorin, cinnamic prevents rat hearts from ischemia/reperfusion injury via endothelial nitric oxide pathway.

    Pharmacognosy Magazine 11(42):292 (2015) PMID 25829767 PMCID PMC4378126

    The objective was to investigate the endothelial nitric oxide synthase (eNOS/NO) pathway is involved or not in the protective effects of glycyrrhizic, ferulic, paeoniflorin, cinnamic (GFPC) in myocardial ischemia-reperfusion injury Sprague-Dawley rats. Ischemia-reperfusion (I/R) model was made b...
  13. Solitary juvenile xanthogranuloma with tibial involvement: a case report.

    International journal of clinical and experimen... 8(1):164 (2015) PMID 25755703 PMCID PMC4348839

    Juvenile xanthogranuloma (JXG) is a rare disease that is part of a spectrum of histiocytic dendritic cell disorders. Most patients present with a solitary cutaneous lesion; however, others present with extracutaneous manifestations or even with systemic involvement. We present the first report o...
  14. Early sensory protection in reverse end-to-side neurorrhaphy to improve the functional recovery of chronically denervated muscle in rat: a pilot study.

    Journal of Neurosurgery 121(2):415 (2014) PMID 24878291

    Early innervation by sensory nerves has been proposed to prevent atrophy of chronically denervated muscle, but conventional end-to-end (ETE) neurorrhaphy has been demonstrated to have adverse effects on muscle contractile function. The aim of the present study was to investigate the potential fo...
  15. Improved peripheral nerve regeneration with sustained release nerve growth factor microspheres in small gap tubulization.

    American journal of translational research 6(4):413 (2014) PMID 25075258 PMCID PMC4113503

    To evaluate the long-term results of the use of nerve growth factor (NGF)-loaded poly-D, L-lactide-co-glycolide (PLGA) microspheres for improve nerve regeneration with small gap tubulization. NGF microspheres were prepared by a modified W/O/W emulsion solvent evaporation method. Forty-eight male...
  16. Electrical stimulation promotes regeneration of defective peripheral nerves after delayed repair intervals lasting under one month.

    PLoS ONE 9(9):e105045 (2014) PMID 25181499 PMCID PMC4152131

    Electrical stimulation (ES) has been proven to be an effective means of enhancing the speed and accuracy of nerve regeneration. However, these results were recorded when the procedure was performed almost immediately after nerve injury. In clinical settings, most patients cannot be treated immed...
  17. The effect of lentivirus-mediated PSPN genetic engineering bone marrow mesenchymal stem cells on Parkinson's disease rat model.

    PLoS ONE 9(8):e105118 (2014) PMID 25118697 PMCID PMC4132064

    Persephin (PSPN) is one of the neurotrophic factors of the glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) which have been found to promote the survival of specific populations of neurons. The aim of this study was to assess the potential therapeutic function of gene-mod...
  18. Therapeutic effect of intravenous infusion of perfluorocarbon emulsion on LPS-induced acute lung injury in rats.

    PLoS ONE 9(1):e87826 (2014) PMID 24489970 PMCID PMC3905038

    Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are the leading causes of death in critical care. Despite extensive efforts in research and clinical medicine, mortality remains high in these diseases. Perfluorocarbon (PFC), a chemical compound known a...
  19. Comparison of road traffic injury characteristics between local versus floating migrant patients in a tertiary hospital between 2007 and 2010.

    PLoS ONE 9(1):e82640 (2014) PMID 24475023 PMCID PMC3903469

    The aim of this study is to give a description of the road traffic injuries (RTIs) characteristics of floating migrant population by comparing with those of local residents in a harbor city of China. A population-based descriptive study was carried out between 2007 and 2010 with RTI patient reco...
  20. NF-κB signaling pathway confers neuroblastoma cells migration and invasion ability via the regulation of CXCR4.

    Medical Science Monitor 20:2746 (2014) PMID 25527973 PMCID PMC4280060

    Accumulating evidence implicates the transcription factor NF-κB as a positive mediator of tumor metastasis, but the molecular mechanism(s) involved in this process remains largely unknown. In this study, we investigated the role of NF-κB signaling pathway in the regulation of CXC chemokine recep...