1. The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation.

    Redox Biology 8:98 (2016) PMID 26773873 PMCID PMC4731949

    Oxidative stress-induced retinal pigment epithelial (RPE) cell damage is an important factor in the pathogenesis of age-related macular degeneration (AMD). Previous studies have shown that RTA 408, a synthetic triterpenoid compound, potently activates Nrf2. This study aimed to investigate the pr...
  2. The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma.

    Clinical Cancer Research 22(11):2684 (2016) PMID 26819453

    Responses to therapy with chimeric antigen receptor T cells recognizing CD19 (CART19, CTL019) may vary by histology. Mantle cell lymphoma (MCL) represents a B-cell malignancy that remains incurable despite novel therapies such as the BTK inhibitor ibrutinib, and where data from CTL019 therapy ar...
  3. Immobilization of wild giant panda (Ailuropoda melanoleuca) with dexmedetomidine-tiletamine-zolazepam.

    Veterinary Anaesthesia & Analgesia 43(3):333 (2016) PMID 26332691

    To assess the effects and utility of dexmedetomidine combined with tiletamine and zolazepam (dexMTZ) to immobilize the wild giant panda. Prospective clinical study. Seven giant pandas (Ailuropoda melanoleuca), five males and two females, aged 7-20 years and weighing 69.2-132.9 kg. Once an animal...
  4. Multifunctional lanthanide-organic frameworks for fluorescent sensing, gas separation and catalysis.

    Dalton Transactions (Print Edition) 45(9):3743 (2016) PMID 26815197

    Two lanthanide MOFs based on 3,3'-((2,3,6,7-tetramethoxyanthracene-9,10-diyl)bis(4,1-phenylene))diacrylic acid (H2LOMe), [Eu(LOMe)1.5(H2O)2]·3.5DMA·2H2O (1) and [Pr(LOMe)(H2O)4]·2.5DMA·3H2O (2) were synthesized under solvothermal conditions. Complex 1 displayed a 2D net with single nodal 44-sql ...
  5. Unprecedented Solvent-Dependent Sensitivities in Highly Efficient Detection of Metal Ions and Nitroaromatic Compounds by a Fluorescent Barium Metal-Organic Framework.

    Inorganic Chemistry 55(4):1782 (2016) PMID 26845287

    The assembly of a fluorescent dicarboxylate ligand with a barium ion resulted in the formation of a 3D metal-organic framework, Ba5(ADDA)5(EtOH)2(H2O)3·5DMF (UPC-17), based on a 1D rod-shaped secondary building unit. The unprecedented solvent-dependent sensitivities of UPC-17 for the detection o...
  6. Enhanced Conversion Efficiencies in Dye-Sensitized Solar Cells Achieved through Self-Assembled Platinum(II) Metallacages.

    Scientific reports 6:29476 (2016) PMID 27404912 PMCID PMC4941399

    Two-component self-assembly supramolecular coordination complexes with particular photo-physical property, wherein unique donors are combined with a single metal acceptor, can be utilized for many applications including in photo-devices. In this communication, we described the synthesis and char...
  7. A Zn Metal-Organic Framework with High Stability and Sorption Selectivity for CO2.

    Inorganic Chemistry 54(22):10587 (2015) PMID 26503174

    A three-dimensional porous Zn metal-organic framework (UPC-12) with high thermal and chemical stability was isolated in high yield and purity from a hydrothermal reaction. UPC-12 exhibits high selectivity for CO2 due to the formation of hydrogen bonds between CO2 molecules and the -COOH groups e...
  8. DENTAL ABNORMALITIES OF EIGHT WILD QINLING GIANT PANDAS (AILUROPODA MELANOLEUCA QINLINGENSIS), SHAANXI PROVINCE, CHINA.

    Journal of Wildlife Diseases 51(4):849 (2015) PMID 26280879

    Eight adult (six male and two female) wild Qinling giant pandas (Ailuropoda melanoleuca qinlingensis) from China National Foping Nature Reserve were tracked, and their dental data collected and recorded from October 2010 to April 2014. Each panda had dental abnormalities of varying severity. Den...
  9. AMPK Plays a Dual Role in Regulation of CREB/BDNF Pathway in Mouse Primary Hippocampal Cells.

    Journal of Molecular Neuroscience 56(4):782 (2015) PMID 25645685

    The hippocampus is vulnerable to damage under conditions of ischemia and hypoxia, causing multiple mental illnesses. cAMP response element-binding protein (CREB) plays a pivotal role in preventing the apoptosis of neurons and many other cells. Here, we found that AMP-activated protein kinase (AM...
  10. [Effects of high-flux hemodialysis on FGF-23 and micro-inflammatory state in end-stage renal diseases patients].

    Zhonghua Yixue Zazhi 95(26):2074 (2015) PMID 26710869

    To explore the effects of high-flux hemodialysis (HFHD) on fibroblast growth factor 23 (FGF-23) and micro-inflammatory state in end-stage renal diseases (ESRD) patients to understand the advantages of HFHD in reducing complications in ESRD patients. A total of 60 subjects sheduled for hemodialys...
  11. Tuning the Dimensionality of Interpenetration in a Pair of Framework-Catenation Isomers To Achieve Selective Adsorption of CO2 and Fluorescent Sensing of Metal Ions.

    Inorganic Chemistry 54(13):6084 (2015) PMID 26086802

    A pair of framework-catenation isomers (UPC-19 and UPC-20) based on an anthracene-functionality dicarboxylate ligand were synthesized and characterized for the first time through tuning of the dimensionality of interpenetration. The interpenetration dimensionality significantly influences the pr...
  12. [The increased level of IL-17 in stomach and up-regulated splenic Th17 cell frequency and IL-17 mRNA level in rats infected with Helicobacter pylori].

    Xi bao yu fen zi mian yi xue za zhi = Chinese j... 31(6):779 (2015) PMID 26062421

    To investigate the variation of Th17 cell frequency and IL-17 level in rats infected with Helicobacter pylori (Hp). A total of 30 rats were used to be infected with Hp by intragastric administration of bacterial suspension. Every 10 rats were sacrificed after 3, 6 and 9 weeks, respectively. The ...
  13. Glutaredoxin 1 (Grx1) Protects Human Retinal Pigment Epithelial Cells From Oxidative Damage by Preventing AKT Glutathionylation.

    Investigative Ophthalmology & Visual Science 56(5):2821 (2015) PMID 25788646

    Glutaredoxin 1 (Grx1) belongs to the oxidoreductase family and is a component of the endogenous antioxidant defense system. However, its physiological function remains largely unknown. In this study, we investigated whether and how Grx1 overexpression protects the retinal pigment epithelial (RPE...
  14. Hydrothermal synthesis of bamboo-shaped nanosheet KNb3O8 with enhanced photocatalytic activity

    Journal of Alloys and Compounds 627:117 (2015)

    A new type of bamboo-shaped KNb3O8 nanosheet was synthesized by using a two-step hydrothermal method. In addition, the photocatalytic degradation performances of the bamboo-shaped KNb3O8 nanosheet and a rod-like KNb3O8 prepared by using molted salt method were also investigated and com...
  15. miR-134 regulates ischemia/reperfusion injury-induced neuronal cell death by regulating CREB signaling.

    Journal of Molecular Neuroscience 55(4):821 (2015) PMID 25316150

    microRNA-134 (miR-134) has been reported to be a brain-specific miRNA and is differently expressed in brain tissues subjected to ischemic injury. However, the underlying mechanism of miR-134 in regulating cerebral ischemic injury remains poorly understood. The current study was designed to delin...
  16. [Patients' medical activities as viewed from medical case records of South Ridge].

    Zhonghua yi shi za zhi (Beijing, China : 1980) 45(2):73 (2015) PMID 26420408

    There are plenty of materials recorded in the medical case records of the South Ridge. Through these records, it is possible to understand the patients' idea of their confidence toward the doctors, changing of invited doctors, pharmacological views, religious behaviors for inviting doctors and g...
  17. Effects of Tissue-Type Plasminogen Site-Specific Transgene in Gelatin-Coated Dacron on the Fibrinolysis Activity of Rabbit Left Atrium.

    Acta Cardiological Sinica 31(2):144 (2015) PMID 27122861 PMCID PMC4804880

    To investigate the effects of tissue-type plasminogen activator (tPA) gene transfer with left-atrium local positioning on the fibrinolytic activity of rabbit left atrial blood. A total of 48 rabbits were randomly divided into 3 groups (n = 16): gene therapy, vector control, and blank control gro...
  18. Sclerosing rhabdomyosarcoma presenting on the knee-joint.

    Indian Journal of Pathology and Microbiology 58(3):335 (2015) PMID 26275257

    Sclerosing rhabdomyosarcoma is a rare pathological diagnosis that easily misdiagnosed. The majority of cases reported the tumor increased rapidly in size and the Ki-67 proliferation index ranged from 10% to 60%. Here, we report the first case of the tumor increased very slowly for 20 years and t...
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  19. GMP production and characterization of leucine zipper-tagged tumor necrosis factor-related apoptosis-inducing ligand (LZ-TRAIL) for phase I clinical trial.

    European Journal of Pharmacology 740:722 (2014) PMID 24929054

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) exhibits potent antitumor activity in a wide range of cancers without deleterious side effects on normal tissues. Several TRAIL derivatives have been developed to improve its pharmacokinetics and therapeutic effects through strategi...
  20. [A clinical series of 80 patients with adenosquamous carcinoma of pancreas].

    Zhonghua wai ke za zhi [Chinese journal of surg... 52(9):658 (2014) PMID 25410777

    To raise the awareness of adenosquamous carcinoma of pancreas and discuss the treatment of it. Clinical data of 80 cases of pancreas adenosquamous carcinoma patients in the Department of Pancreas Surgery of Changhai Hospital of Second Military Medical University from December 2003 to October 201...