1. Safety and immunogenicity of dry powder measles vaccine administered by inhalation: A randomized controlled Phase I clinical trial.

    Vaccine 32(50):6791 (2014) PMID 25446830

    Measles is a highly infectious respiratory disease which causes 122,000 deaths annually. Although measles vaccine is extremely safe and effective, vaccine coverage could be improved by a vaccine that is more easily administered and transported. We developed an inhalable dry powder measles vaccin...
  2. Safety and immunogenicity of dry powder measles vaccine administered by inhalation: a randomized controlled Phase I clinical trial.

    Vaccine 32(50):6791 (2014) PMID 25446830

    Measles is a highly infectious respiratory disease which causes 122,000 deaths annually. Although measles vaccine is extremely safe and effective, vaccine coverage could be improved by a vaccine that is more easily administered and transported. We developed an inhalable dry powder measles vaccin...
  3. Safety and immunogenicity of dry powder measles vaccine administered by inhalation: A randomized controlled Phase I clinical trial

    Vaccine 32(50):6791 (2014)

    Background Measles is a highly infectious respiratory disease which causes 122,000 deaths annually. Although measles vaccine is extremely safe and effective, vaccine coverage could be improved by a vaccine that is more easily administered and transported. We developed an inha...
  4. Geographic analysis of individual and environmental risk factors for hypospadias births.

    Birth Defects Research Part A: Clinical and Mol... 100(11):887 (2014) PMID 25196538 PMCID PMC4245315

    Hypospadias is a relatively common birth defect affecting the male urinary tract. We explored the etiology of hypospadias by examining its spatial distribution in North Carolina and the spatial clustering of residuals from individual and environmental risk factors. We used data collected by the ...
  5. Geographic analysis of individual and environmental risk factors for hypospadias births.

    Birth Defects Research Part A: Clinical and Mol... 100(11):887 (2014) PMID 25196538 PMCID PMC4245315

    Hypospadias is a relatively common birth defect affecting the male urinary tract. We explored the etiology of hypospadias by examining its spatial distribution in North Carolina and the spatial clustering of residuals from individual and environmental risk factors. We used data collected by the ...
  6. Mixed germ cell tumour after testotoxicosis.

    Clinical Endocrinology 81(5):786 (2014) PMID 24467671

  7. Downstaging disease in patients with hepatocellular carcinoma outside of Milan criteria: strategies using drug-eluting bead chemoembolization.

    Journal of Vascular and Interventional Radiology 24(11):1613 (2013) PMID 24060436

    To assess downstaging rates in patients with United Network for Organ Sharing stage T3N0M0 hepatocellular carcinoma (HCC) treated with doxorubicin-eluting bead transarterial chemoembolization to meet Milan criteria for transplantation. A single-center retrospective review of 239 patients treated...
  8. Downstaging Disease in Patients with Hepatocellular Carcinoma Outside of Milan Criteria: Strategies Using Drug-eluting Bead Chemoembolization

    Journal of Vascular and Interventional Radiology 24(11):1613 (2013)

    Purpose To assess downstaging rates in patients with United Network for Organ Sharing stage T3N0M0 hepatocellular carcinoma (HCC) treated with doxorubicin-eluting bead transarterial chemoembolization to meet Milan criteria for transplantation.
  9. Evaluation and management of mild traumatic brain injury: an Eastern Association for the Surgery of Trauma practice management guideline.

    The Journal of Trauma and Acute Care Surgery 73(5 Suppl 4):S307 (2012) PMID 23114486

    An estimated 1.1 million people sustain a mild traumatic brain injury (MTBI) annually in the United States. The natural history of MTBI remains poorly characterized, and its optimal clinical management is unclear. The Eastern Association for the Surgery of Trauma had previously published a set o...
  10. Epidemiology of urban tuberculosis in the United States, 2000-2007.

    American Journal of Public Health 101(7):1256 (2011) PMID 21566031 PMCID PMC3110232

    We investigated tuberculosis (TB) incidence rates and characteristics of patients with TB in large US cities. Using the Centers for Disease Control and Prevention's National Tuberculosis Surveillance System data, we categorized 48 cities annually from 2000 to 2007 as reporting decreasing or nond...
  11. Burn wound infections.

    Clinical Microbiology Reviews 19(2):403 (2006) PMID 16614255 PMCID PMC1471990

    Burns are one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality. Significant thermal injuries induce a state of immunosuppression that predisposes burn patients to infectious co...
  12. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

    Molecular Cell 14(5):553 (2004) PMID 15175151

  13. A Unified Nomenclature for Protein Subunits of Mediator Complexes Linking Transcriptional Regulators to RNA Polymerase II

    Molecular Cell 14(5):553 (2004)

  14. A1 receptor and adenosinergic homeostatic regulation of sleep-wakefulness: effects of antisense to the A1 receptor in the cholinergic basal forebrain.

    Journal of Neuroscience 23(10):4278 (2003) PMID 12764116 PMCID PMC2002519

    We hypothesized that adenosine, acting via the A1 receptor, is a key factor in the homeostatic control of sleep. The increase in extracellular levels of adenosine during prolonged wakefulness is thought to facilitate the transition to sleep by reducing the discharge activity of wakefulness-promo...
  15. Comparison of inhaled isopropyl alcohol and intravenous ondansetron for treatment of postoperative nausea.

    AANA Journal 71(2):127 (2003) PMID 12776641

    Postoperative nausea, a common complication in patients receiving general anesthesia, was studied in this randomized investigation to compare the efficacy of 70% inhaled isopropyl alcohol and intravenous ondansetron. For the study, 100 healthy women, ASA physical status I or II, scheduled for ou...
  16. Beta-glucuronidase activity in saliva: relationship to clinical periodontal parameters.

    Journal of Periodontology 74(3):353 (2003) PMID 12710755

    Beta-glucuronidase (betaG) in gingival crevicular fluid (GCF), a marker of neutrophil influx into the crevicular environment, has previously been shown to be correlated with periodontal clinical parameters at individual sites (probing depth and clinical attachment level). Furthermore, elevated l...
  17. Orexin neurons of the hypothalamus express adenosine A1 receptors.

    Brain Research 944(1-2):190 (2002) PMID 12106679

    Adenosine is a putative sleep factor with effects mainly mediated by the A1 receptor. Recent studies have implicated the hypothalamic orexin/hypocretin-containing neurons in the control of sleep-wakefulness. To help determine if adenosine might play a role in the control of orexin neurons, immun...
  18. Cerebellar mutism associated with a midbrain cavernous malformation. Case report and review of the literature.

    Journal of Neurosurgery 96(3):607 (2002) PMID 11883849

    The authors report a case of cerebellar mutism arising from a hemorrhagic midbrain cavernous malformation in a 14-year-old boy. No cerebellar lesion was identified; however, edema of the dorsal midbrain was noted on postoperative magnetic resonance images. Dysarthric speech spontaneously returne...
  19. A clinical methods study of the effects of triclosan dentifrices on gingivitis over six months.

    The Journal of clinical dentistry 13(6):240 (2002) PMID 12518498

    The basic design for human clinical trials which examine prevention of gingivitis recurrence is well known. However, the anti-gingivitis efficacy of triclosan-containing dentifrices has not been routinely demonstrated using this design, regardless of formulation. In an effort to better understan...
  20. Orexin neurons of the hypothalamus express adenosine A1 receptors

    Brain Research 944(1):190 (2002)

    Adenosine is a putative sleep factor with effects mainly mediated by the A1 receptor. Recent studies have implicated the hypothalamic orexin/hypocretin-containing neurons in the control of sleep–wakefulness. To help determine if adenosine might play a role in the control of orexin neurons, ...