1. Asymmetric Construction of 2,3-Dihydroisoxazoles via an Organocatalytic Formal [3 + 2] Cycloaddition of Enynes with N-Hydroxylamines.

    Organic Letters 18(16):3972 (2016) PMID 27482852

    An organocatalytic asymmetric formal [3 + 2] cycloaddition of enynones with N-hydroxylamines has been described. A newly designed multifunctional organocatalyst was found to be highly effective, and the method allowed the synthesis of a variety of 2,3-dihydroisoxazoles in good yields with excell...
  2. Online Deformable Object Tracking Based on Structure-Aware Hyper-Graph.

    Image Processing, IEEE Transactions on 25(8):3572 (2016) PMID 27214901

    Recent advances in online visual tracking focus on designing part-based model to handle the deformation and occlusion challenges. However, previous methods usually consider only the pairwise structural dependences of target parts in two consecutive frames rather than the higher order constraints...
  3. Quantitative theory for the longitudinal relaxation time of blood water.

    Magnetic Resonance in Medicine 76(1):270 (2016) PMID 26285144 PMCID PMC4758918

    To propose and evaluate a model for the blood water T1 that takes into account the effects of hematocrit fraction, oxygenation fraction, erythrocyte hemoglobin concentration, methemoglobin fraction, and plasma albumin concentration. Whole blood and lysed blood T1 data were acquired at magnetic f...
  4. Flexible Circuits and Soft Actuators by Printing Assembly of Graphene.

    ACS Applied Materials & Interfaces 8(19):12369 (2016) PMID 27124494

    An effective way to improve the electrical conductivity of printed graphene patterns was demonstrated by realizing the assembly of giant graphene oxide sheets during the printing process. The synergetic effect of printing-induced orientation and evaporation-induced interfacial assembly facilitat...
  5. Resting State fMRI Demonstrates a Disturbance of the Cerebello-Cortical Circuit in Essential Tremor.

    Brain Topography 29(3):412 (2016) PMID 26868003

    Individuals with essential tremor (ET) have postural and active movement abnormalities. Disturbances in the cerebello-thalamo-cortical circuit may contribute to the several motor symptoms of ET. Resting state fMRI provides a valuable, noninvasive tool to study intrinsic activation in the human b...
  6. Enhancers as non-coding RNA transcription units: recent insights and future perspectives.

    Nature Reviews: Genetics 17(4):207 (2016) PMID 26948815

    Networks of regulatory enhancers dictate distinct cell identities and cellular responses to diverse signals by instructing precise spatiotemporal patterns of gene expression. However, 35 years after their discovery, enhancer functions and mechanisms remain incompletely understood. Intriguingly, ...
  7. Recent developments in the synthesis and utilization of chiral β-aminophosphine derivatives as catalysts or ligands.

    Chemical Society Reviews 45(6):1657 (2016) PMID 26776280

    In the last few years, the research area of chiral β-aminophosphines capable of promoting a wide range of diverse organic transformations has attracted more attention. Their derivatives constitute attractive reagents towards this end, due to their stability, low toxicity and ease of handling. Th...
  8. High-speed ultrashort pulse fiber ring laser using charcoal nanoparticles.

    Applied Optics 55(9):2149 (2016) PMID 27140546

    A mode-locked erbium-doped fiber ring laser that is easy to set up is proposed and experimentally demonstrated to generate a high-repetition-rate optical pulse train with an ultrashort pulse width. The laser combines a rational harmonic mode-locking technique and charcoal nanoparticles as satura...
  9. Three-dimensional visualization of arsenic stimulated mouse liver sinusoidal by FIB-SEM approach.

    Protein & Cell 7(3):227 (2016) PMID 26856874 PMCID PMC4791422

  10. Nanoparticle Based Curve Arrays for Multirecognition Flexible Electronics.

    Advanced Materials (FRG) 28(7):1369 (2016) PMID 26644086

    Assembly of nanoparticles into controllable micro or nanocurve circuits by a feasible strategy is demonstrated. The curves, with various tortuosity morphologies, have tunable resistive strain sensitivity, which can be integrated into a multi-analysis flexible sensor. The curve-based sensor can r...
  11. Phase diagrams for clathrate hydrates of methane, ethane, and propane from first-principles thermodynamics.

    Physical Chemistry Chemical Physics 18(4):3272 (2016) PMID 26745181

    Natural gas hydrates are inclusion compounds composed of major light hydrocarbon gaseous molecules (CH4, C2H6, and C3H8) and a water clathrate framework. Understanding the phase stability and formation conditions of natural gas hydrates is crucial for their future exploitation and applications a...
  12. Recent Progress in Dehydro(genative) Diels-Alder Reaction.

    Chemistry: A European Journal 22(5):1558 (2016) PMID 26786814

    In recent years, remarkable progress has been made in dehydro or dehydrogenative Diels-Alder (D-A) reactions. This Minireview gives an overview of the major two strategies for dehydro(genative) Diels-Alder reactions, which differ in dehydrogenation and D-A cyclization sequence. Reactions in whic...
  13. Construction of human single-chain variable fragment antibodies of medullary thyroid carcinoma and single photon emission computed tomography/computed tomography imaging in tumor-bearing nude mice.

    Oncology Reports 35(1):171 (2016) PMID 26498224

    Medullary thyroid carcinoma (MTC) is a rare tumor of the endocrine system with poor prognosis as it exhibits high resistance against conventional therapy. Recent studies have shown that monoclonal antibodies labeled with radionuclide have become important agents for diagnosing tumors. To elucida...
  14. Mutant-specific BRAF and CD117 immunocytochemistry potentially facilitate risk stratification for papillary thyroid carcinoma in fine-needle aspiration biopsy specimens.

    Tumor Biology 37(1):611 (2016) PMID 26240026

    The study aims to test whether combination of mutant-specific BRAF and CD117 immunocytochemical (ICC) staining stratifies probability for papillary thyroid carcinoma (PTC) in thyroid fine-needle aspiration biopsy (FNAB) specimens. A consecutive cohort of cases diagnosed as atypia of undetermined...
  15. Effects of Lycium barbarum Polysaccharides on Apoptosis, Cellular Adhesion, and Oxidative Damage in Bone Marrow Mononuclear Cells of Mice Exposed to Ionizing Radiation Injury.

    BioMed Research International 2016:4147879 (2016) PMID 27314019 PMCID PMC4899582

    Lycium barbarum has been used for more than 2500 years as a traditional herb and food in China. We investigated the effects of Lycium barbarum polysaccharides (LBP) on apoptosis, oxidative damage, and expression of adhesion molecules in bone marrow mononuclear cells (BMNC) of mice injured by ion...
  16. Fate of gold and base metals during metamorphic devolatilization of a pelite

    Geochimica et Cosmochimica Acta 171:338 (2015)

    Scavenging of gold during metamorphic devolatilization is a widely accepted model for fluid and metal sourcing in orogenic gold deposits. In order to further constrain this process and quantify the capacity of autogenous fluids to release metals from pelites, we investigated the behavi...
  17. Paper-Based Active Tactile Sensor Array.

    Advanced Materials (FRG) 27(44):7130 (2015) PMID 26450138

    A paper-based active tactile sensor -array (PATSA) with a dynamic sensitivity of 0.35 V N(-1) is demonstrated. The pixel position of the PATSA can be routed by analyzing the real-time recording voltages in the pressing process. The PATSA performance, which remains functional when removing partia...
  18. Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity

    Cell 163(2):520 (2015)

  19. The role of ¹⁸F-FDG PET or ¹⁸F-FDG-PET/CT in the evaluation of solitary pulmonary nodules.

    European Journal of Radiology 84(10):2032 (2015) PMID 26094866

    Even with the recent advance in diagnostic tools and techniques, solitary pulmonary nodules (SPNs) remains a major clinical challenge for all doctors involved in their study. There are a wide range of diagnoses of benign and malignant lesions that can manifest as SPNs. Positron emission tomograp...
  20. TNF-α suppression and osteoprotegerin overexpression inhibits wear debris-induced inflammation and osteoclastogenesis in vitro.

    International Journal of Artificial Organs 38(10):565 (2015) PMID 26541276

    Periprosthetic osteolysis, involving RANK/RANKL/osteoprotegerin (OPG) and TNF-α/NFκB signaling, contributes to bone resorption and inflammation. We constructed lentivirus vectors to inhibit TNF-α and enhance OPG expression and assessed their impacts on wear debris-induced inflammation and osteoc...