1. Managing symptoms and maximizing quality of life after preventive interventions for cancer risk reduction.

    Current Opinion in Obstetrics & Gynecology 27(1):40 (2015) PMID 25502430

    The prevention of breast, ovarian and endometrial cancer frequently involves hormonal or surgical interventions. Each of these may have noncancerous sequelae and can affect quality of life in women with hereditary cancer syndromes. The purpose of this review is to discuss the medical management ...
  2. Collagenase clostridium histolyticum in patients with Dupuytren's contracture: results from POINT X, an open-label study of clinical and patient-reported outcomes.

    Journal of Hand Surgery (European Volume) 40(2):124 (2015) PMID 24470559

    In POINT X, a study designed to reflect clinical practice and patient treatment choices, 254 European patients received open-label collagenase for Dupuytren's contracture. The most severely affected joint was treated first in 74% of patients. In total, 52%, 41%, 7%, and 1% of patients selected t...
  3. Managing symptoms and maximizing quality of life after preventive interventions for cancer risk reduction.

    Current Opinion in Obstetrics & Gynecology 27(1):40 (2015) PMID 25502430

    The prevention of breast, ovarian and endometrial cancer frequently involves hormonal or surgical interventions. Each of these may have noncancerous sequelae and can affect quality of life in women with hereditary cancer syndromes. The purpose of this review is to discuss the medical management ...
  4. Polycyclic aromatic hydrocarbon exposure in household air pollution from solid fuel combustion among the female population of Xuanwei and Fuyuan counties, China.

    Environmental Science & Technology 48(24):14632 (2014) PMID 25393345 PMCID PMC4270388

    Exposure to polycyclic aromatic hydrocarbons (PAHs) from burning "smoky" (bituminous) coal has been implicated as a cause of the high lung cancer incidence in the counties of Xuanwei and Fuyuan, China. Little is known about variations in PAH exposure from throughout the region nor how fuel sourc...
  5. Polycyclic Aromatic Hydrocarbon Exposure in Household Air Pollution from Solid Fuel Combustion among the Female Population of Xuanwei and Fuyuan Counties, China.

    Environmental Science & Technology 48(24):14632 (2014) PMID 25393345 PMCID PMC4270388

    Exposure to polycyclic aromatic hydrocarbons (PAHs) from burning "smoky" (bituminous) coal has been implicated as a cause of the high lung cancer incidence in the counties of Xuanwei and Fuyuan, China. Little is known about variations in PAH exposure from throughout the region nor how fuel sourc...
  6. Polycyclic Aromatic Hydrocarbon Exposure in Household Air Pollution from Solid Fuel Combustion among the Female Population of Xuanwei and Fuyuan Counties, China.

    Environmental Science & Technology 48(24):14632 (2014) PMID 25393345

    Exposure to polycyclic aromatic hydrocarbons (PAHs) from burning "smoky" (bituminous) coal has been implicated as a cause of the high lung cancer incidence in the counties of Xuanwei and Fuyuan, China. Little is known about variations in PAH exposure from throughout the region nor how fuel sourc...
  7. Household air pollution and lung cancer in China: a review of studies in Xuanwei.

    Ai zheng = Aizheng = Chinese journal of cancer 33(10):471 (2014) PMID 25223911 PMCID PMC4198749

    Over half of the world's population is exposed to household air pollution from the burning of solid fuels at home. Household air pollution from solid fuel use is a leading risk factor for global disease and remains a major public health problem, especially in low- and mid-income countries. This ...
  8. Prevalence, risk factors and vaccination efficacy of contagious ovine ecthyma (orf) in England.

    Veterinary Record 175(13):326 (2014) PMID 24996900

    Orf is a viral disease found in English sheep flocks which can cause economic losses. It is a zoonosis with little epidemiological research available in the UK. In 2012, 3000 questionnaires were sent to English sheep farms in order to investigate the prevalence of orf, determine vaccination effi...
  9. Prevalence, risk factors and vaccination efficacy of contagious ovine ecthyma (orf) in England.

    Veterinary Record 175(13):326 (2014) PMID 24996900

    Orf is a viral disease found in English sheep flocks which can cause economic losses. It is a zoonosis with little epidemiological research available in the UK. In 2012, 3000 questionnaires were sent to English sheep farms in order to investigate the prevalence of orf, determine vaccination effi...
  10. Household air pollution and lung cancer in China: a review of studies in Xuanwei.

    Ai zheng = Aizheng = Chinese journal of cancer 33(10):471 (2014) PMID 25223911 PMCID PMC4198749

    Over half of the world's population is exposed to household air pollution from the burning of solid fuels at home. Household air pollution from solid fuel use is a leading risk factor for global disease and remains a major public health problem, especially in low- and mid-income countries. This ...
  11. Backbone resonance assignments of the 42 kDa enzyme arginine kinase in the transition state analogue form.

    Biomolecular NMR Assignments 8(2):335 (2014) PMID 23893440 PMCID PMC3906217

    Nearly complete backbone resonance assignments for the 357 residue, 42 kDa enzyme arginine kinase in a transition state analogue (TSA) complex are presented. The TSA is a quaternary complex of arginine kinase, MgADP, arginine, and nitrate. About 93% (320 of 344) of the non-proline backbone amide...
  12. Rodent consumption in Khon Kaen Province, Thailand.

    The Southeast Asian journal of tropical medicin... 45(5):1209 (2014) PMID 25417525

    Rodents are important reservoirs of rodent-borne infections worldwide, including Southeast Asia and Northeast Thailand (Isaan), where rodent consumption may be a source of rodent-borne diseases. The behavior of consuming rodents is related to a population's traditions, knowledge, cultural, and h...
  13. A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes.

    PLoS Neglected Tropical Diseases 8(9):e3145 (2014) PMID 25188325 PMCID PMC4154664

    Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological functions. The process is catalyzed by myristo...
  14. Rodent consumption in Khon Kaen Province, Thailand.

    The Southeast Asian journal of tropical medicin... 45(5):1209 (2014) PMID 25417525

    Rodents are important reservoirs of rodent-borne infections worldwide, including Southeast Asia and Northeast Thailand (Isaan), where rodent consumption may be a source of rodent-borne diseases. The behavior of consuming rodents is related to a population's traditions, knowledge, cultural, and h...
  15. Spatial, demographic and clinical patterns of Angiostrongylus vasorum infection in the dog population of Southern England.

    Veterinary Record 175(6):148 (2014) PMID 24878572

    A retrospective study was carried out to provide updated knowledge of the spatial pattern of Angiostrongylus vasorum infection in Southern England and to investigate associations between selected host characteristics (age, breed, sex), risk of infection and clinical presentation (cardiorespirato...
  16. Personal and indoor PM2.5 exposure from burning solid fuels in vented and unvented stoves in a rural region of China with a high incidence of lung cancer.

    Environmental Science & Technology 48(15):8456 (2014) PMID 25003800 PMCID PMC4123931

    The combustion of biomass and coal is the dominant source of household air pollution (HAP) in China, and contributes significantly to the total burden of disease in the Chinese population. To characterize HAP exposure related to solid fuel use and ventilation patterns, an exposure assessment stu...
  17. Measurement of the cosmic microwave background polarization lensing power spectrum with the POLARBEAR experiment.

    Physical Review Letters 113(2):021301 (2014) PMID 25062161

    Gravitational lensing due to the large-scale distribution of matter in the cosmos distorts the primordial cosmic microwave background (CMB) and thereby induces new, small-scale B-mode polarization. This signal carries detailed information about the distribution of all the gravitating matter betw...
  18. Measurement of the cosmic microwave background polarization lensing power spectrum with the POLARBEAR experiment.

    Physical Review Letters 113(2):021301 (2014) PMID 25062161

    Gravitational lensing due to the large-scale distribution of matter in the cosmos distorts the primordial cosmic microwave background (CMB) and thereby induces new, small-scale B-mode polarization. This signal carries detailed information about the distribution of all the gravitating matter betw...
  19. Heterogeneity in coal composition and implications for lung cancer risk in Xuanwei and Fuyuan counties, China.

    Environment International 68:94 (2014) PMID 24721117

    Xuanwei and Fuyuan counties in Yunnan Province, China have among the highest lung cancer rates in the country. This has been associated with the domestic combustion of bituminous coal (referred to as "smoky" coal). Additionally, significant geographical variation in cancer rates among smoky coal...
  20. Factors affecting perceived stigma in leprosy affected persons in western Nepal.

    PLoS Neglected Tropical Diseases 8(6):e2940 (2014) PMID 24901307 PMCID PMC4046961

    There are various factors which construct the perception of stigma in both leprosy affected persons and unaffected persons. The main purpose of this study was to determine the level of perceived stigma and the risk factors contributing to it among leprosy affected person attending the Green Past...