1. On the evolution of bacterial multicellularity

    Current Opinion in Microbiology 24:21 (2015)

    • Many bacteria have multicellular lifecycle phases, falling into three broad categories. • Predation, nutrient scarcity, and environmental variability may have le...
  2. From Cell Differentiation to Cell Collectives: Bacillus subtilis Uses Division of Labor to Migrate.

    PLoS Biology 13(4):e1002141 (2015) PMID 25894589

    The organization of cells, emerging from cell-cell interactions, can give rise to collective properties. These properties are adaptive when together cells can face environmental challenges that they separately cannot. One particular challenge that is important for microorganisms is migration. In...
  3. New tools for comparing microscopy images: quantitative analysis of cell types in Bacillus subtilis.

    Journal of Bacteriology 197(4):699 (2015) PMID 25448819

    Fluorescence microscopy is a method commonly used to examine individual differences between bacterial cells, yet many studies still lack a quantitative analysis of fluorescence microscopy data. Here we introduce some simple tools that microbiologists can use to analyze and compare their microsco...
  4. New Tools for Comparing Microscopy Images: Quantitative Analysis of Cell Types in Bacillus subtilis.

    Journal of Bacteriology 197(4):699 (2015) PMID 25448819

    Fluorescence microscopy is a method commonly used to examine individual differences between bacterial cells, yet many studies still lack a quantitative analysis of fluorescence microscopy data. Here we introduce some simple tools that microbiologists can use to analyze and compare their microsco...
  5. New tools for comparing microscopy images: quantitative analysis of cell types in Bacillus subtilis.

    Journal of Bacteriology 197(4):699 (2015) PMID 25448819 PMCID PMC4334194

    Fluorescence microscopy is a method commonly used to examine individual differences between bacterial cells, yet many studies still lack a quantitative analysis of fluorescence microscopy data. Here we introduce some simple tools that microbiologists can use to analyze and compare their microsco...
  6. New tools for comparing microscopy images: quantitative analysis of cell types in Bacillus subtilis.

    Journal of Bacteriology 197(4):699 (2015) PMID 25448819 PMCID PMC4334194

    Fluorescence microscopy is a method commonly used to examine individual differences between bacterial cells, yet many studies still lack a quantitative analysis of fluorescence microscopy data. Here we introduce some simple tools that microbiologists can use to analyze and compare their microsco...
  7. Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis.

    Scientific reports 5:9383 (2015) PMID 25807046

    Bacilli are ubiquitous low G+C environmental Gram-positive bacteria that produce a wide assortment of specialized small molecules. Although their natural product biosynthetic potential is high, robust molecular tools to support the heterologous expression of large biosynthetic gene clusters in B...
  8. Sporulation during growth in a gut isolate of Bacillus subtilis.

    Journal of Bacteriology 196(23):4184 (2014) PMID 25225273 PMCID PMC4248874

    Sporulation by Bacillus subtilis is a cell density-dependent response to nutrient deprivation. Central to the decision of entering sporulation is a phosphorelay, through which sensor kinases promote phosphorylation of Spo0A. The phosphorelay integrates both positive and negative signals, ensurin...
  9. Sporulation during Growth in a Gut Isolate of Bacillus subtilis.

    Journal of Bacteriology 196(23):4184 (2014) PMID 25225273 PMCID PMC4248874

    Sporulation by Bacillus subtilis is a cell density-dependent response to nutrient deprivation. Central to the decision of entering sporulation is a phosphorelay, through which sensor kinases promote phosphorylation of Spo0A. The phosphorelay integrates both positive and negative signals, ensurin...
  10. Sporulation during growth in a gut isolate of Bacillus subtilis.

    Journal of Bacteriology 196(23):4184 (2014) PMID 25225273 PMCID PMC4248874

    Sporulation by Bacillus subtilis is a cell density-dependent response to nutrient deprivation. Central to the decision of entering sporulation is a phosphorelay, through which sensor kinases promote phosphorylation of Spo0A. The phosphorelay integrates both positive and negative signals, ensurin...
  11. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.

    Chemistry & Biology 21(11):1557 (2014) PMID 25308276 PMCID PMC4252625

    YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observed that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all ...
  12. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.

    Chemistry & Biology 21(11):1557 (2014) PMID 25308276 PMCID PMC4252625

    YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observed that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all ...
  13. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.

    Chemistry & Biology 21(11):1557 (2014) PMID 25308276 PMCID PMC4252625

    YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observed that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all ...
  14. Structural and Functional Analysis of Bacillus subtilis YisP Reveals a Role of Its Product in Biofilm Production.

    Chemistry & Biology 21(11):1557 (2014) PMID 25308276 PMCID PMC4252625

    YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observed that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all ...
  15. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production.

    Chemistry & Biology 21(11):1557 (2014) PMID 25308276 PMCID PMC4252625

    YisP is involved in biofilm formation in Bacillus subtilis and has been predicted to produce C30 isoprenoids. We determined the structure of YisP and observed that it adopts the same fold as squalene and dehydrosqualene synthases. However, the first aspartate-rich motif found in essentially all ...
  16. Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization.

    Microbial Biotechnology 7(6):589 (2014) PMID 25351041 PMCID PMC4265077

    Salmonella Typhimurium inhabits a variety of environments and is able to infect a broad range of hosts. Throughout its life cycle, some hosts can act as intermediates in the path to the infection of others. Aspergillus niger is a ubiquitous fungus that can often be found in soil or associated to...
  17. Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization.

    Microbial Biotechnology 7(6):589 (2014) PMID 25351041 PMCID PMC4265077

    Salmonella Typhimurium inhabits a variety of environments and is able to infect a broad range of hosts. Throughout its life cycle, some hosts can act as intermediates in the path to the infection of others. Aspergillus niger is a ubiquitous fungus that can often be found in soil or associated to...
  18. Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization.

    Microbial Biotechnology 7(6):589 (2014) PMID 25351041

    Salmonella Typhimurium inhabits a variety of environments and is able to infect a broad range of hosts. Throughout its life cycle, some hosts can act as intermediates in the path to the infection of others. Aspergillus niger is a ubiquitous fungus that can often be found in soil or associated to...
  19. Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization.

    Microbial Biotechnology 7(6):589 (2014) PMID 25351041 PMCID PMC4265077

    Salmonella Typhimurium inhabits a variety of environments and is able to infect a broad range of hosts. Throughout its life cycle, some hosts can act as intermediates in the path to the infection of others. Aspergillus niger is a ubiquitous fungus that can often be found in soil or associated to...
  20. Mutualistic interaction between Salmonella enterica and Aspergillus niger and its effects on Zea mays colonization.

    Microbial Biotechnology 7(6):589 (2014) PMID 25351041

    Salmonella Typhimurium inhabits a variety of environments and is able to infect a broad range of hosts. Throughout its life cycle, some hosts can act as intermediates in the path to the infection of others. Aspergillus niger is a ubiquitous fungus that can often be found in soil or associated to...