1. "Translational" medicine: transforming SPRINT findings into clinical practice.

    Journal of the American Society of Hypertension 10(5):382 (2016) PMID 27155246

  2. Creating and Maintaining a Successful Service Line in an Academic Medical Center at the Dawn of Value-Based Care: Lessons Learned From the Heart and Vascular Service Line at UMass Memorial Health Care.

    Academic Medicine 90(10):1340 (2015) PMID 26222322

    The service line (SL) model has been proven to help shift health care toward value-based services, which is characterized by coordinated, multidisciplinary, high-quality, and cost-effective care. However, academic medical centers struggle with how to effectively set up SL structures that overcom...
  3. A New Species of Culicoides (Selfia) (Diptera: Ceratopogonidae) from Southeastern Utah.

    Journal of Medical Entomology 52(5):842 (2015) PMID 26336237

    A new species of biting midge, Culicoides (Selfia) moabensis, is described and illustrated from southeastern Utah. Its relationship to Culicoides (Selfia) multipunctatus Malloch and Culicoides (Selfia) brookmani Wirth is discussed, and modifications to existing keys to adult males and females of...
  4. New agents for hyperkalemia.

    New England Journal of Medicine 372(16):1569 (2015) PMID 25875264

  5. Racial impact of diurnal variations in blood pressure on cardiovascular events in chronic kidney disease.

    Journal of the American Society of Hypertension 9(4):299 (2015) PMID 25891362

    Ambulatory blood pressure parameters, nocturnal dipping and morning surge, are associated with cardiovascular outcomes in several populations. While significant variation exists between racial groups in ambulatory blood pressure measurements and the incidence of cardiovascular disease, the effec...
  6. Current and Future Treatment of Hypertension in the SPRINT Era.

    Methodist DeBakey cardiovascular journal 11(4):206 (2015) PMID 27057288 PMCID PMC4814005

    Based on the SPRINT trial, it is highly likely that new SPRINT-era guidelines will establish a blood pressure (BP) goal of < 130/80 mm Hg for those aged 50 or older who are at high risk for a cardiovascular event. In this group, SPRINT demonstrated that assignment to an intensive-treatment systo...
  7. Emerging Concepts in the Diagnosis and Treatment of Hypertension in the SPRINT Era.

    Methodist DeBakey cardiovascular journal 11(4):204 (2015) PMID 27057287 PMCID PMC4814004

  8. Population health: ASH and the American health care revolution: leadership message from the American Society of Hypertension.

    Journal of the American Society of Hypertension 8(6):365 (2014) PMID 24952651

  9. Relationship of left ventricular hypertrophy and diastolic function with cardiovascular and renal outcomes in African Americans with hypertensive chronic kidney disease.

    Hypertension 62(3):518 (2013) PMID 23836799

    African Americans with hypertension are at high risk for adverse outcomes from cardiovascular and renal disease. Patients with stage 3 or greater chronic kidney disease have a high prevalence of left ventricular (LV) hypertrophy and diastolic dysfunction. Our goal was to study prospectively the ...
  10. Treating hypertension in patients with left ventricular dysfunction: hitting the fairway and avoiding the rough.

    Current Heart Failure Reports 10(2):157 (2013) PMID 23563890

    Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to...
  11. Association of BP variability with mortality among African Americans with CKD.

    Clinical Journal of the American Society of Nep... 8(5):731 (2013) PMID 23493382 PMCID PMC3641624

    Increased systolic BP visit-to-visit variability (SBV) may be associated with higher overall mortality and cardiovascular events. However, few studies have examined these associations in patients with CKD, and the relation of SBV with CKD progression and ESRD has not been shown. This study analy...
  12. A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease.

    Hypertension 61(1):82 (2013) PMID 23172931 PMCID PMC3523681

    The objective of our study was to determine the effects of 2 antihypertensive drug dose schedules (PM dose and add-on dose) on nocturnal blood pressure (BP) in comparison with usual therapy (AM dose) in blacks with hypertensive chronic kidney disease and controlled office BP. In a 3-period, cros...
  13. Relationship between ambulatory BP and clinical outcomes in patients with hypertensive CKD.

    Clinical Journal of the American Society of Nep... 7(11):1770 (2012) PMID 22935847 PMCID PMC3488952

    Abnormal ambulatory BP (ABP) profiles are commonplace in CKD, yet the prognostic value of ABP for renal and cardiovascular outcomes is uncertain. This study assessed the relationship of baseline ABP profiles with CKD progression and subsequent cardiovascular outcomes to determine the prognostic ...
  14. Controversies in blood pressure goal guidelines and masked hypertension.

    Annals of the Lyceum of Natural History of New ... 1254:115 (2012) PMID 22548577

    In uncomplicated hypertension, <140/90 mmHg is the treatment goal for individuals aged 18-79 and between 140 mmHg and 150 mmHg in those 80 years of age. Inhibitors of the renin-angiotensin-aldosterone system, as well as calcium channel blockers, are universally accepted as first-line therapy in ...
  15. Pulmonary Artery Catheter (PAC) Accuracy and Efficacy Compared with Flow Probe and Transcutaneous Doppler (USCOM): An Ovine Cardiac Output Validation.

    Critical Care Research and Practice 2012:621496 (2012) PMID 22649718 PMCID PMC3357512

    Background. The pulmonary artery catheter (PAC) is an accepted clinical method of measuring cardiac output (CO) despite no prior validation. The ultrasonic cardiac output monitor (USCOM) is a noninvasive alternative to PAC using Doppler ultrasound (CW). We compared PAC and USCOM CO measurements ...
  16. Blood pressure and treatment of persons with hypertension as it relates to cognitive outcomes including executive function.

    Journal of the American Society of Hypertension 6(5):309 (2012) PMID 22995799

  17. Left ventricular hypertrophy by electrocardiography and echocardiography in the African American Study of Kidney Disease Cohort Study.

    Journal of the American Society of Hypertension 6(3):193 (2012) PMID 22341790

    Although electrocardiographic criteria for diagnosing left ventricular hypertrophy have a low sensitivity in the general population, their test characteristics have not been evaluated in the high-prevalence group of American Americans with chronic kidney disease. The purpose of the current study...
  18. Intensive blood-pressure control in hypertensive chronic kidney disease.

    New England Journal of Medicine 363(10):918 (2010) PMID 20818902 PMCID PMC3662974

    In observational studies, the relationship between blood pressure and end-stage renal disease (ESRD) is direct and progressive. The burden of hypertension-related chronic kidney disease and ESRD is especially high among black patients. Yet few trials have tested whether intensive blood-pressure ...
  19. Safety and U.S. Regulatory considerations in the nonclinical use of medical ultrasound devices.

    Ultrasound in Medicine & Biology 36(8):1224 (2010) PMID 20447750

    Ultrasound imaging has been used for medical purposes for over 50 years and has an excellent safety record. Ultrasonic fetal scanning is generally considered safe and is properly used when medical information on a pregnancy is needed. However, ultrasound energy delivered to the fetus cannot be r...
  20. Risk of hyperkalemia in nondiabetic patients with chronic kidney disease receiving antihypertensive therapy.

    Archives of Internal Medicine 169(17):1587 (2009) PMID 19786678

    The incidence and factors associated with hyperkalemia in patients with chronic kidney disease (CKD) treated with angiotensin converting enzyme inhibitors (ACEIs) and other antihypertensive drugs was investigated using the African American Study of Kidney Disease and Hypertension (AASK) database...