Neuroprotective effect of microRNA-99a against focal cerebral ischemia-reperfusion injury in mice.
Journal of the Neurological Sciences 355(1-2):113 (2015)
MicroRNA-99a (miR-99a) has been reported to function as a tumor suppressor through regulating cell cycle and apoptosis. But its clinical significance in ischemic stroke and its function in cerebral ischemia-reperfusion (I/R) injury remained unknown. Herein transient middle cerebral artery occlus...
Diet and risk of adult leukemia: a multicenter case-control study in China.
Cancer Causes & Control 26(8):1141 (2015)
Epidemiologic studies on diet and leukemia risk have shown inconsistent results. This study examined the associations between dietary factors and the risk of adult leukemia in Chinese populations.
A multicenter case-control study was conducted in southeast and northeast China between 2008 and 20...
Dual-Functions of miR-373 and miR-520c by Differently Regulating the Activities of MMP2 and MMP9.
Journal Of Cellular Physiology 230(8):1862 (2015)
MicroRNA-520c (miR-520c) and microRNA-373 (miR-373) are originally characterized as both oncogenes and tumor suppressors in different types of human cancers. In this study, we found that translation of mRNA of MT1-MMP, an oncogene related to tumor metastasis, was well inhibited by miR-520c and m...
Biochemical pregnancy and spontaneous abortion in first IVF cycles are negative predictors for subsequent cycles: an over 10,000 cases cohort study.
Archives of Gynecology and Obstetrics 292(2):453 (2015)
To identify whether biochemical pregnancy (BP) and spontaneous abortion (SA) cases have the same clinical characteristics in assisted reproductive therapy (ART), and to assess its predictive value for the subsequent cycles.
Retrospectively reviewed 12,174 cycles in the first in vitro fertilizati...
MicroRNA-429 inhibits the migration and invasion of colon cancer cells by targeting PAK6/cofilin signaling.
Oncology Reports 34(2):707 (2015)
MicroRNAs (miRs), a class of non-coding RNAs 18-25 nucleotides in length, can lead to mRNA degradation or inhibit protein translation by directly binding to the 3'-untranslational region (UTR) of their target mRNAs. The deregulation of miR-429 has been suggested to be involved in the development...
Potential protection of taurine on antioxidant system and ATPase in brain and blood of rats exposed to aluminum.
Biotechnology Letters 37(8):1579 (2015)
Taurine (Tau) is used in clinical treatments but its protection of brains against aluminum-induced oxidative damage has been explored for the first time. The positive effect of Tau was studied on the activities of antioxidant enzymes and ATPase.
Aluminum (Al) intake caused significant increaseme...
Reconfigurable assembly of superparamagnetic colloids confined in thermo-reversible microtubes.
Soft Matter 11(31):6201 (2015)
Structural transformations of superparamagnetic colloids confined within self-assembled microtubes are studied by systematically varying tube-colloid size ratios and external magnetic field directions. A magnetic field parallel to microtubes may stretch non-linear chains like zigzag chains into ...
Transcriptome and MassARRAY analysis for identification of transcripts and SNPs for growth traits of the swimming crab Portunus trituberculatus.
Gene 566(2):229 (2015)
Portunus trituberculatus is an important farmed crustacean in China. Growth traits are important economic traits that are controlled by many genes. The aim of this study was to screen growth-related genes using Illumina paired-end sequencing technology, and to identify growth-related SNPs in P. ...
Profiling of aldehyde-containing compounds by stable isotope labelling-assisted mass spectrometry analysis.
Analyst (Cambridge UK) 140(15):5276 (2015)
We developed a strategy for non-targeted profiling of aldehyde-containing compounds by stable isotope labelling in combination with liquid chromatography-double neutral loss scan-mass spectrometry (SIL-LC-DNLS-MS) analysis. A pair of stable isotope labelling reagents (4-(2-(trimethylammonio)etho...
Correction to "Pregnancy-Induced Metabolic Phenotype Variations in Maternal Plasma".
Journal of Proteome Research 14(7):3005 (2015)
Study on π-π Interaction in H- and J-Aggregates of Poly(3-hexylthiophene) Nanowires by Multiple Techniques.
Journal of Physical Chemistry B 119(26):8446 (2015)
There has been intense interest in understanding the self-assembled structure of conductive polymer nanowires due to the potential application in photovoltaics area. In the present study, free-standing poly(3-hexylthiophene) (P3HT) thin films consisting of H-aggregated and recently reported J-ag...
Astragaloside prevents BDL-induced liver fibrosis through inhibition of notch signaling activation.
Journal of Ethnopharmacology 169:200 (2015)
Huangqi decoction was first described in Prescriptions of the Bureau of Taiping People׳s Welfare Pharmacy in the Song Dynasty (AD1078). It consists of Radix Astragali (Astragalus membranceus (Fisch.) Bge. Root, Huangqi) and Radix Glycyrrhizae (Glycyrrhiza uralensis Fisch., root and rhizome, Ganc...
Determination of Phytochelatins in Rice by Stable Isotope Labeling Coupled with Liquid Chromatography-Mass Spectrometry.
Journal of Agricultural and Food Chemistry 63(25):5935 (2015)
A highly sensitive method was developed for the detection of phytochelatins (PCs) in rice by stable isotope labeling coupled with liquid chromatography-electrospray ionization-tandem mass spectrometry (IL-LC-ESI-MS/MS) analysis. A pair of isotope-labeling reagents [ω-bromoacetonylquinolinium bro...
Defect Engineering and Phase Junction Architecture of Wide-Bandgap ZnS for Conflicting Visible Light Activity in Photocatalytic H2 Evolution.
ACS Applied Materials & Interfaces 7(25):13915 (2015)
ZnS is among the superior photocatalysts for H2 evolution, whereas the wide bandgap restricts its performance to only UV region. Herein, defect engineering and phase junction architecture from a controllable phase transformation enable ZnS to achieve the conflicting visible-light-driven activiti...
Effects of Fuzhuan Brick-Tea Water Extract on Mice Infected with E. coli O157:H7.
Nutrients 7(7):5309 (2015)
Fuzhuan brick-tea extract (FBTE) affects the physiology of mice infected with Escherichia coli O157:H7. For 10 consecutive days, 0.05, 0.5, and 1.0 g/mL FBTE was administered intragastrically to three groups of infected Kunming mice, and changes in immunological function, hematology, and histopa...
Immunomodulation and liver protection of Yinchenhao decoction against concanavalin A-induced chronic liver injury in mice.
Journal of Integrative Medicine (JIM) 13(4):262 (2015)
This study investigated the immunoregulatory and protective roles of Yinchenhao decoction, a compound of Chinese herbal medicine, in a mouse model of concanavalin A (ConA)-induced chronic liver injury.
Female BalB/c mice were randomly divided into 4 groups: normal control, ConA model, ConA model...
(1)Rational design of a charge shunt: modification upon crystal facet engineering of semiconductor photocatalysts.
Chemical Communications 51(56):11186 (2015)
Another excellent carrier shunt is artificially bridged over different exposed facets of a semiconductor, to achieve a unique architecture with superior photoactivity, which is mainly attributed to the facet-driven charge dual-selectivity-channel separation mechanism. This novel concept may brea...
Helical TiO2 Nanotube Arrays Modified by Cu-Cu2O with Ultrahigh Sensitivity for the Nonenzymatic Electro-oxidation of Glucose.
ACS Applied Materials & Interfaces 7(23):12719 (2015)
A novel Cu-Cu2O/TiO2/Ti electrode for the nonenzymatic electro-oxidation of glucose has been fabricated by secondary anodic oxidation combined with the electrodeposition method. It represents a new type of copper oxide-TiO2 complex nanostructure that demonstrates a new application. At the potent...
A near-infrared fluorescent probe for the selective detection of HNO in living cells and in vivo.
Analyst (Cambridge UK) 140(13):4576 (2015)
Nitroxyl (HNO), the one-electron reduced and protonated analogue of nitric oxide (NO), demonstrates distinctive bio-pharmacological effects in the treatment of cardiovascular disorders. Herein, we design and synthesize a near-infrared (NIR) metal-free fluorescent probe Cyto-JN for the detection ...
Double-step CO2 sorption and guest-induced single-crystal-to-single-crystal transformation in a flexible porous framework.
Dalton Transactions (Print Edition) 44(22):10141 (2015)
A new 2D highly flexible and breathing porous framework [CuL(Me2NH)]·DMF·H2O () (H3L = 5-(4'-carboxylphenoxy)nicotinic acid) has been synthesized using a tritopic linker with a flexible joint. The desolvated framework, [CuL(Me2NH)] (), undergoes structural contraction, and exhibits selective and...