1. In vivo injection of α-bungarotoxin to improve the efficiency of motor endplate labeling.

    Brain and Behavior 6(6):e00468 (2016) PMID 27186443 PMCID PMC4851864

    Motor endplates are composed of a motor neuron terminal and muscle fiber and are distributed in skeletal muscle, causing muscle contraction. However, traditional motor endplate staining methods are limited to the observation of partial skeletal muscle. The procedure was time-consuming due to str...
  2. Profiling of the dynamically alteredgene expression in peripheral nerve injury using NGS RNA sequencing technique.

    American journal of translational research 8(2):871 (2016) PMID 27158375 PMCID PMC4846932

    Functional recovery of peripheral nerve injuries is of major demand in clinical practice worldwide. Although, to some extent, peripheral nervous system can spontaneously regenerate, post-injury recovery is often associated with poor functional outcome. The molecular mechanism controlling the per...
  3. Collateral development and spinal motor reorganization after nerve injury and repair.

    American journal of translational research 8(7):2897 (2016) PMID 27508011 PMCID PMC4969427

    Functional recovery is often unsatisfactory after severe extended nerve defects or proximal nerve trunks injuries repaired by traditional repair methods, as the long regeneration distance for the regenerated axons to reinnervate their original target end-organs. The proximal nerve stump can rege...
  4. A Versatile Multiple Target Detection System Based on DNA Nano-assembled Linear FRET Arrays.

    Scientific reports 6:26879 (2016) PMID 27230484 PMCID PMC4882533

    DNA molecules have been utilized both as powerful synthetic building blocks to create nanoscale architectures and as inconstant programmable templates for assembly of biosensors. In this paper, a versatile, scalable and multiplex detection system is reported based on an extending fluorescent res...
  5. Corrigendum: A Versatile Multiple Target Detection System Based on DNA Nano-assembled Linear FRET Arrays.

    Scientific reports 6:28411 (2016) PMID 27390043 PMCID PMC4936509

  6. Topography of Synchronization of Somatosensory Evoked Potentials Elicited by Stimulation of the Sciatic Nerve in Rat.

    Frontiers in Computational Neuroscience 10:43 (2016) PMID 27199728 PMCID PMC4854893

    Traditionally, the topography of somatosensory evoked potentials (SEPs) is generated based on amplitude and latency. However, this operation focuses on the physical morphology and field potential-power, so it suffers from difficulties in performing identification in an objective manner. In this ...
  7. Peripheral nerve mutilation through biodegradable conduit small gap tubulisation: a multicentre randomised trial

    The Lancet 386:S40 (2015)

    Background Although peripheral nerve injury is repaired by ingenious epineurial neurorrhaphy, functional recovery is usually not satisfactory and is hindered by many factors, including the misconnections of sensory and motor nerve fibres, difficulties in target organ reinnerv...
  8. Changes and trends of pre-hospital emergency disease spectrum in Beijing in 2003–12: a retrospective study

    The Lancet 386:S39 (2015)

    Background Pre-hospital emergency call is a crucial indicator of emergency disease spectrum. Since Beijing has changed substantially in economy and population, analysis of the trend of the emergency disease spectrum can greatly contribute to pre-hospital emergency planning. ...
  9. Road traffic injury and rescue system in China.

    The Lancet 385(9978):1622 (2015) PMID 25943819

  10. Early nerve protection with anterior interosseous nerve in modified end-to-side neurorrhaphy repairs high ulnar nerve injury: a hypothesis of a novel surgical technique.

    Artificial Cells, Nanomedicine and Biotechnology 43(2):103 (2015) PMID 24195580

    High ulnar nerve injuries frequently result in poor functional recovery. The prolonged denervation of target muscle largely accounts for the poor functional outcome. There are no approved effective treatments for high ulnar nerve injuries. However, the technique of reverse end-to-side (RETS) off...
  11. Motor function recovery during peripheral nerve multiple regeneration.

    Journal Of Tissue Engineering And Regenerative ... 9(4):415 (2015) PMID 24323657

    Neuronal functional compensation and multiple regenerating axon sprouting occur during peripheral nerve regeneration. Sprouting nerve buds were quantitatively maintained and had matured when multiple injured distal nerves were anastomosed to smaller number of proximal nerve stumps; this has posi...
  12. Healing of cancellous fracture in a novel mouse model.

    American journal of translational research 7(11):2279 (2015) PMID 26807176 PMCID PMC4697708

    Fractures are one of the most prevalent clinical conditions worldwide. Among them, cancellous fracture is a major cause of extremities fractures. Unfortunately, it is largely unknown about how is the healing of cancellous fracture. In the current study, we present a novel cancellous fracture mic...
  13. Specificity of motor axon regeneration: a comparison of recovery following biodegradable conduit small gap tubulization and epineurial neurorrhaphy.

    American journal of translational research 7(1):53 (2015) PMID 25755828 PMCID PMC4346523

    Functional recovery is often unsatisfactory after lesions in the peripheral nervous system despite the strong potential for regeneration and advances in microsurgical techniques. Axonal regeneration in mixed nerve into inappropriate pathways is a major contributing factor to this failure. In thi...
  14. Local administration of IKK small molecule inhibitor may enhance fracture healing in osteoporosis patient.

    International journal of clinical and experimen... 8(1):1411 (2015) PMID 25785147 PMCID PMC4358602

    Osteoporosis is an inflammatory bone disease affecting millions of population worldwide, which often cause increased fracture risks and prolonged fracture healing. Growing evidence suggests that IKK-NF-κB signaling exert inhibitory influence on MSCs osteogenic differentiation and bone formation....
  15. Using suture and locking anatomical bridging plate to fix comminuted mid-shaft clavicle fractures with intramedullary nail assistance in reduction.

    International journal of clinical and experimen... 8(7):11153 (2015) PMID 26379917 PMCID PMC4565300

    During conventional plate fixation of comminuted midshaft fracture of the clavicle, wedge-shaped fragments often need to be fixed with lag screws. A new procedure, which included intramedullary K-wire assistance in reduction, binding fragments by suture, and eventually bridging plate fixation, w...
  16. Surgical treatment for a paraplegic patient induced by congenital factor X deficiency.

    International journal of clinical and experimen... 8(8):13403 (2015) PMID 26550274 PMCID PMC4612959

    Congenital factor X (FX) deficiency is a rare disease which usually leads to coagulation disorders. We reported a case of paraplegic patient induced by traumatic spinal epidural hematoma which was associated with congenital FX deficiency. The treatments of this patient included elevating FX acti...
  17. The change tendency of PI3K/Akt pathway after spinal cord injury.

    American journal of translational research 7(11):2223 (2015) PMID 26807170 PMCID PMC4697702

    Spinal cord injury (SCI) refers to the damage of spinal cord's structure and function due to a variety of causes. At present, many scholars have confirmed that apoptosis is the main method of secondary injury in spinal cord injury. In view of understanding the function of PI3K/Akt pathway on spi...
  18. Cauda equina syndrome caused by isolated spinal extramedullary-intradural cauda equina metastasis is the primary symptom of small cell lung cancer: a case report and review of the literatrure.

    International journal of clinical and experimen... 8(6):10044 (2015) PMID 26309698 PMCID PMC4538121

    To describe a case of extramedullary-intradural metastases causing cauda equina syndrome (CES) as the primary syndrome of lung cancer, and to review the pertinent medical literature. Intradural spinal metastasis is rare, accounting for 6% of all spinal metastases. Of all primary lesion types, lu...
  19. Biliary tract and pancreatic surgery complicated by acute pancreatitis: a clinical analysis.

    International journal of clinical and experimen... 8(4):6295 (2015) PMID 26131243 PMCID PMC4484006

    To study the clinical treatment features of biliary tract and pancreatic surgery complicated by acute pancreatitis. A retrospective analysis of 21 cases of biliary tract and pancreatic surgery complicated by acute pancreatitis in the Department of General Surgery in our hospital during May 2005 ...
  20. A novel specialized staging system for cancellous fracture healing, distinct from traditional healing pattern of diaphysis corticalfracture?

    International journal of clinical and experimen... 8(1):1301 (2015) PMID 25785130 PMCID PMC4358585

    Metaphysis cancellous bone fracture is one of the most common fracture types in clinical orthopedic practice. The specialized healing process of cancellous bone fracture has long been ignored by the academic society. Comparing with diaphyseal cortical bone healing, cancellous bone healing showed...