1. Long-Distance Dispersal Shaped Patterns of Human Genetic Diversity in Eurasia.

    Molecular Biology and Evolution 33(4):946 (2016) PMID 26637555 PMCID PMC4776706

    Most previous attempts at reconstructing the past history of human populations did not explicitly take geography into account or considered very simple scenarios of migration and ignored environmental information. However, it is likely that the last glacial maximum (LGM) affected the demography ...
  2. Facilitating the production of ISO-compliant metadata of geospatial datasets

    International Journal of Applied Earth Observat... 44:239 (2016)

    • Facilitate the production of standardized metadata by embedding the generation of description in data production workflows. • Link data with metadata. Metadata i...
  3. An interoperable cloud-based scientific GATEWAY for NDVI time series analysis

    Computer Standards & Interfaces 41:79 (2015)

    Processing of high-resolution time series satellite images typically requires a large amount of computational resources and time. We introduce here a scientific gateway for computing the Normalized Difference Vegetation Index (NDVI) time series data. Based on a distributed workflow usi...
  4. Environmental data gaps in Black Sea catchment countries: INSPIRE and GEOSS State of Play

    Environmental Science & Policy 46:13 (2015)

    • Large-scale gap analysis was performed on existing observation systems, networks, services and datasets for the Black Sea catchment. • Gaps and areas are identif...
  5. Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals.

    PLoS Genetics 10(9):e1004572 (2014) PMID 25254375 PMCID PMC4177621

    The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample ...
  6. Influence of admixture and paleolithic range contractions on current European diversity gradients.

    Molecular Biology and Evolution 30(1):57 (2013) PMID 22923464

    Cavalli-Sforza and Edwards (Analysis of human evolution. 1963. In: Geerts SJ, editor. Genetics today: Proceedings of the 11th International Congress of Genetics, The Hague, The Netherlands. New York: Pergamon. p. 923-993.) initiated the representation of genetic relationships among human populat...
  7. WPS mediation: An approach to process geospatial data on different computing backends

    Computers & Geosciences 47:20 (2012)

    The OGC Web Processing Service (WPS) specification allows generating information by processing distributed geospatial data made available through Spatial Data Infrastructures (SDIs). However, current SDIs have limited analytical capacities and various problems emerge when trying to use...
  8. Reconstructing Native American population history.

    Nature 488(7411):370 (2012) PMID 22801491 PMCID PMC3615710

    The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved. One contentious issue is whether the settlement occurred by means of a single migration or multiple streams of migration from Siberia. The...
  9. Parsimony-based pedigree analysis and individual-based landscape genetics suggest topography to restrict dispersal and connectivity in the endangered capercaillie

    Biological Conservation 152:241 (2012)

    Highlights ► Noninvasive genetic assessment of dispersal and functional connectivity in capercaillie (Tetrao urogallus). ► Least-cost path analysis suggest mountains, but not land use types to hamper dispersal. ► New parsimony-based pedigree analysis shows frequent dispersal ...
  10. Consequences of range contractions and range shifts on molecular diversity.

    Molecular Biology and Evolution 29(1):207 (2012) PMID 21778191

    Due to past and current climatic changes, range contractions and range shifts are essential stages in the history of a species. However, unlike range expansions, the molecular consequences of these processes have been little investigated. In order to fill this gap, we simulated patterns of molec...
  11. Grid-enabled Spatial Data Infrastructure for environmental sciences: Challenges and opportunities

    Future Generation Computer Systems 27(3):292 (2011)

    Spatial Data Infrastructures (SDIs) are being widely used in the environmental sciences to share, discover, visualize and retrieve geospatial data through Open Geospatial Consortium (OGC) web services. However, SDIs have limited analytical capabilities, an essential task to turn data into u...
  12. SPLATCHE2: a spatially explicit simulation framework for complex demography, genetic admixture and recombination.

    PMID 20956243

    SPLATCHE2 is a program to simulate the demography of populations and the resulting molecular diversity for a wide range of evolutionary scenarios. The spatially explicit simulation framework can account for environmental heterogeneity and fluctuations, and it can manage multiple population sourc...
  13. Contrasting patterns of nuclear and mtDNA diversity in Native American populations.

    Annals of Human Genetics 74(6):525 (2010) PMID 20887376

    We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreeme...
  14. Combining genetic, historical and geographical data to reconstruct the dynamics of bioinvasions: application to the cane toad Bufo marinus.

    Molecular Ecology Resources 10(5):886 (2010) PMID 21565099

    We developed a spatially explicit model of a bioinvasion and used an approximate Bayesian computation (ABC) framework to make various inferences from a combination of genetic (microsatellite genotypes), historical (first observation dates) and geographical (spatial coordinates of introduction an...
  15. A first step towards inferring levels of long-distance dispersal during past expansions.

    Molecular Ecology Resources 10(5):902 (2010) PMID 21565100

    Improving the realism of spatially explicit demographic models is important for better inferring the history of past populations and for understanding the genetic bases of adaptation and speciation. One particular type of demographic event to take into account is long-distance dispersal (LDD). T...
  16. Principal component analysis under population genetic models of range expansion and admixture.

    Molecular Biology and Evolution 27(6):1257 (2010) PMID 20097660

    In a series of highly influential publications, Cavalli-Sforza and colleagues used principal component (PC) analysis to produce maps depicting how human genetic diversity varies across geographic space. Within Europe, the first axis of variation (PC1) was interpreted as evidence for the demic di...
  17. Inferring past demography using spatially explicit population genetic models.

    Human Biology 81(2-3):141 (2009) PMID 19943741

    Inferring the past demography of human populations has been classically approached through data from the archaeological record but more recently by the use of genetic data from contemporary samples. Building realistic demographic models at the continental scale is a necessary step toward the imp...
  18. Surfing during population expansions promotes genetic revolutions and structuration.

    Trends in Ecology & Evolution 23(7):347 (2008) PMID 18502536

    Recent studies have shown that low-frequency alleles can sometimes surf on the wave of advance of a population range expansion, reaching high frequencies and spreading over large areas. Using microbial populations, Hallatschek and colleagues have provided the first experimental evidence of surfi...
  19. Geographic patterns of genome admixture in Latin American Mestizos.

    PLoS Genetics 4(3):e1000037 (2008) PMID 18369456 PMCID PMC2265669

    The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture across Latin America has yet been attempted. Here, we report an analysis of ad...
  20. Colonization history of the Swiss Rhine basin by the bullhead (Cottus gobio): inference under a Bayesian spatially explicit framework.

    Molecular Ecology 17(3):757 (2008) PMID 18194169

    The present distribution of freshwater fish in the Alpine region has been strongly affected by colonization events occurring after the last glacial maximum (LGM), some 20,000 years ago. We use here a spatially explicit simulation framework to model and better understand their colonization dynami...