1. Comparative Cost-Effectiveness of Conservative or Intensive Blood Pressure Treatment Guidelines in Adults Aged 35-74 Years: The Cardiovascular Disease Policy Model.

    Hypertension 68(1):88 (2016) PMID 27181996

    The population health effect and cost-effectiveness of implementing intensive blood pressure goals in high-cardiovascular disease (CVD) risk adults have not been described. Using the CVD Policy Model, CVD events, treatment costs, quality-adjusted life years, and drug and monitoring costs were si...
  2. Gait Speed as a Guide for Blood Pressure Targets in Older Adults: A Modeling Study.

    Journal of the American Geriatrics Society 64(5):1015 (2016) PMID 27225357

    To evaluate the potential for gait speed to inform decisions regarding optimal systolic blood pressure targets in older adults. Forecasting study from 2014 to 2023 using the Cardiovascular Disease Policy Model, a Markov model. National Health and Nutrition Examination Survey. U.S. adults aged 60...
  3. Projected Impact of Salt Restriction on Prevention of Cardiovascular Disease in China: A Modeling Study.

    PLoS ONE 11(2):e0146820 (2016) PMID 26840409 PMCID PMC4739496

    To estimate the effects of achieving China's national goals for dietary salt (NaCl) reduction or implementing culturally-tailored dietary salt restriction strategies on cardiovascular disease (CVD) prevention. The CVD Policy Model was used to project blood pressure lowering and subsequent downst...
  4. Ongoing quality control in digital radiography: Report of AAPM Imaging Physics Committee Task Group 151.

    Medical Physics 42(11):6658 (2015) PMID 26520756

    Quality control (QC) in medical imaging is an ongoing process and not just a series of infrequent evaluations of medical imaging equipment. The QC process involves designing and implementing a QC program, collecting and analyzing data, investigating results that are outside the acceptance levels...
  5. Statins for Primary Prevention in Adults Aged 75 Years or Older.

    Annals of Internal Medicine 163(6):482 (2015) PMID 26370015

  6. The Cost-Effectiveness of Low-Cost Essential Antihypertensive Medicines for Hypertension Control in China: A Modelling Study.

    PLOS Medicine 12(8):e1001860 (2015) PMID 26241895 PMCID PMC4524696

    Hypertension is China's leading cardiovascular disease risk factor. Improved hypertension control in China would result in result in enormous health gains in the world's largest population. A computer simulation model projected the cost-effectiveness of hypertension treatment in Chinese adults, ...
  7. Research in academic medical centers: two threats to sustainable support.

    Science Translational Medicine 7(289):289fs22 (2015) PMID 26019216

    Reductions in federal support and clinical revenue jeopardize biomedical research and, in turn, clinical medicine. Copyright © 2015, American Association for the Advancement of Science.
  8. Cost-effectiveness and population impact of statins for primary prevention in adults aged 75 years or older in the United States.

    Annals of Internal Medicine 162(8):533 (2015) PMID 25894023 PMCID PMC4476404

    Evidence to guide primary prevention in adults aged 75 years or older is limited. To project the population impact and cost-effectiveness of statin therapy in adults aged 75 years or older. Forecasting study using the Cardiovascular Disease Policy Model, a Markov model. Trial, cohort, and nation...
  9. Cost-effectiveness of hypertension therapy according to 2014 guidelines.

    New England Journal of Medicine 372(5):447 (2015) PMID 25629742 PMCID PMC4403858

    On the basis of the 2014 guidelines for hypertension therapy in the United States, many eligible adults remain untreated. We projected the cost-effectiveness of treating hypertension in U.S. adults according to the 2014 guidelines. We used the Cardiovascular Disease Policy Model to simulate drug...
  10. 40 years of training physician-scientists: a journey from clinical pearls to evidence-based practice and policies.

    Annals of Internal Medicine 161(10 Suppl):S2 (2014) PMID 25402399

  11. Impact on cardiovascular disease events of the implementation of Argentina's national tobacco control law.

    Tobacco Control 23(2):e6 (2014) PMID 23092886 PMCID PMC4026283

    Argentina's congress passed a tobacco control law that would enforce 100% smoke-free environments for the entire country, strong and pictorial health warnings on tobacco products and a comprehensive advertising ban. However, the Executive Branch continues to review the law and it has not been fu...
  12. Cost-effectiveness of optimal use of acute myocardial infarction treatments and impact on coronary heart disease mortality in China.

    Circulation: Cardiovascular Quality and Outcomes 7(1):78 (2014) PMID 24425706 PMCID PMC4191653

    The cost-effectiveness of the optimal use of hospital-based acute myocardial infarction (AMI) treatments and their potential impact on coronary heart disease (CHD) mortality in China is not well known. The effectiveness and costs of optimal use of hospital-based AMI treatments were estimated by ...
  13. An intellectual agenda for hospitalists: lessons from bloodletting.

    Journal Of Hospital Medicine 8(7):418 (2013) PMID 23401423

  14. How provocative is provocative testing?: comment on "Yield of routine provocative cardiac testing among patients in an emergency department-based chest pain unit.

    JAMA Internal Medicine 173(12):1134 (2013) PMID 23689511

  15. Projected impact of urbanization on cardiovascular disease in China.

    International Journal of Public Health 57(5):849 (2012) PMID 22918518 PMCID PMC3465962

    The Coronary Heart Disease (CHD) Policy Model-China, a national scale cardiovascular disease computer simulation model, was used to project future impact of urbanization. Populations and cardiovascular disease incidence rates were stratified into four submodels: North-Urban, South-Urban, North-R...
  16. Bleeding is rarely good for you.

    Circulation 126(2):169 (2012) PMID 22777663

  17. Letter by Lee and Goldman regarding article, "Development and validation of a risk calculator for prediction of cardiac risk after surgery".

    Circulation 125(7):e385; author reply e386 (2012) PMID 22354985

  18. Using stress testing to guide primary prevention of coronary heart disease among intermediate-risk patients: a cost-effectiveness analysis.

    Circulation 125(2):260 (2012) PMID 22144567 PMCID PMC3265963

    Noninvasive stress testing might guide the use of aspirin and statins for primary prevention of coronary heart disease, but it is unclear if such a strategy would be cost effective. We compared the status quo, in which the current national use of aspirin and statins was simulated, with 3 other s...
  19. A penny-per-ounce tax on sugar-sweetened beverages would cut health and cost burdens of diabetes.

    Health Affairs 31(1):199 (2012) PMID 22232111

    Sugar-sweetened beverages are a major contributor to the US obesity and diabetes epidemics. Using the Coronary Heart Disease Policy Model, we examined the potential impact on health and health spending of a nationwide penny-per-ounce excise tax on these beverages. We found that the tax would red...
  20. Improving adherence--money isn't the only thing.

    New England Journal of Medicine 365(22):2131 (2011) PMID 22080839