Salt Sensitivity of Blood Pressure: A Scientific Statement From the American Heart Association.
Hypertension 68(3):e7 (2016)
Patterns of Kidney Function Decline Associated with APOL1 Genotypes: Results from AASK.
Clinical Journal of the American Society of Nep... 11(8):1353 (2016)
Trajectories of eGFR in patients with CKD are highly variable. Only a subset of patients with CKD experiences a steady decline in eGFR. The objective of our study was to investigate whether eGFR trajectory patterns differ by APOL1 risk status.
Our study was a longitudinal observational study of ...
National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence.
Hypertension 68(2):281 (2016)
Traditional and non-traditional risk factors for incident peripheral arterial disease among patients with chronic kidney disease.
Nephrology Dialysis Transplantation 31(7):1145 (2016)
The risk of peripheral arterial disease (PAD) is higher in patients with chronic kidney disease (CKD) compared with those without. However, reasons for this increased risk are not fully understood.
We studied risk factors for incident PAD among 3169 participants in the Chronic Renal Insufficienc...
Bariatric surgery is associated with improvement in kidney outcomes.
Kidney International 90(1):164 (2016)
Severe obesity is associated with increased risk of kidney disease. Whether bariatric surgery reduces the risk of adverse kidney outcomes is uncertain. To resolve this we compared the risk of estimated glomerular filtration rate (eGFR) decline of ≥30% and doubling of serum creatinine or end-stag...
Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly.
American Journal of Public Health 106(7):1270 (2016)
To determine the effect of sodium (Na) reduction on occurrence of headaches.
In the Trial of Nonpharmacologic Interventions in the Elderly, 975 men and woman (aged 60-80 years) with hypertension were randomized to a Na-reduction intervention or control group and were followed for up to 36 months...
Individual variation in urinary sodium excretion among adolescent girls on a fixed intake.
Journal of Hypertension 34(7):1290 (2016)
According to traditional understanding of sodium homeostasis, nearly all of daily sodium intake is excreted in urine, with intraindividual variability attributed to variability in dietary sodium intake and urine collection errors.
To analyze the variability of urinary sodium in excretion from a ...
Association Between Adiposity and Left Ventricular Mass in Children With Hypertension.
Journal of Clinical Hypertension 18(7):625 (2016)
Left ventricular hypertrophy (LVH) is prevalent among hypertensive children; however, blood pressure (BP) does not predict its presence. The authors conducted a 1-year prospective cohort study to examine the hypothesis that obesity-related risk factors are associated with left ventricular mass i...
Comparison of Two ELISA Methods and Mass Spectrometry for Measurement of Vitamin D-Binding Protein: Implications for the Assessment of Bioavailable Vitamin D Concentrations Across Genotypes.
Journal of Bone and Mineral Research 31(6):1128 (2016)
Studies using vitamin D-binding protein (DBP) concentrations to estimate free and bioavailable vitamin D have increased dramatically in recent years. Combinations of two single-nucleotide polymorphisms (SNPs) produce three major DBP isoforms (Gc1f, Gc1s, and Gc2). A recent study showed that DBP ...
Effects of Lowering Glycemic Index of Dietary Carbohydrate on Plasma Uric Acid Levels: The OmniCarb Randomized Clinical Trial.
Arthritis & rheumatology (Hoboken, N.J.) 68(5):1281 (2016)
The effects of carbohydrates on plasma uric acid levels are a subject of controversy. We determined the individual and combined effects of carbohydrate quality (the glycemic index) and quantity (the proportion of total daily energy [percentage of carbohydrates]) on uric acid levels.
The impact of continued intervention on weight: Five-year results from the weight loss maintenance trial.
Obesity 24(5):1046 (2016)
In the Weight Loss Maintenance (WLM) Trial, a personal contact (PC) intervention sustained greater weight loss relative to a self-directed (SD) group over 30 months. This study investigated the effects of continued intervention over an additional 30 months and overall weight change across the en...
Validation of the Instant Blood Pressure Smartphone App.
JAMA Internal Medicine 176(5):700 (2016)
Urinary Sodium and Potassium Excretion and CKD Progression.
Journal of the American Society of Nephrology 27(4):1202 (2016)
CKD is a major risk factor for ESRD, cardiovascular disease, and premature death. Whether dietary sodium and potassium intake affect CKD progression remains unclear. We prospectively studied the association of urinary sodium and potassium excretion with CKD progression and all-cause mortality am...
Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study.
Journal of the American Heart Association Cardi... 5(4):e003192 (2016)
As part of its 2020 Impact Goals, the American Heart Association developed the Life's Simple 7 metric for cardiovascular health promotion. The relationship between the Life's Simple 7 metric and incident chronic kidney disease (CKD) is unknown.
We estimated the association between Life's Simple ...
Prevalence and Prognostic Significance of Apparent Treatment Resistant Hypertension in Chronic Kidney Disease: Report From the Chronic Renal Insufficiency Cohort Study.
Hypertension 67(2):387 (2016)
The association between apparent treatment resistant hypertension (ATRH) and clinical outcomes is not well studied in chronic kidney disease. We analyzed data on 3367 hypertensive participants in the Chronic Renal Insufficiency Cohort (CRIC) to determine prevalence, associations, and clinical ou...
Kidney Function and Fracture Risk: The Atherosclerosis Risk in Communities (ARIC) Study.
American Journal of Kidney Diseases 67(2):218 (2016)
People with end-stage renal disease are at high risk for bone fracture. Less is known about fracture risk in milder chronic kidney disease and whether chronic kidney disease-associated fracture risk varies by sex or assessment with alternative kidney markers.
Prospective cohort study.
Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis.
JAMA 315(2):164 (2016)
Identifying patients at risk of chronic kidney disease (CKD) progression may facilitate more optimal nephrology care. Kidney failure risk equations, including such factors as age, sex, estimated glomerular filtration rate, and calcium and phosphate concentrations, were previously developed and v...
Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease.
JAMA 315(20):2200 (2016)
Patients with chronic kidney disease (CKD) are at an increased risk of cardiovascular disease (CVD) compared with the general population. Prior studies have produced contradictory results on the association of dietary sodium intake with risk of CVD, and this relationship has not been investigate...
Vegetarian Diets for Weight Loss: How Strong is the Evidence?
Journal of General Internal Medicine 31(1):9 (2016)
A Dietary Intervention in Urban African Americans: Results of the "Five Plus Nuts and Beans" Randomized Trial.
American Journal of Preventive Medicine 50(1):87 (2016)
Unhealthy diets, often low in potassium, likely contribute to racial disparities in blood pressure. We tested the effectiveness of providing weekly dietary advice, assistance with selection of higher potassium grocery items, and a $30 per week food allowance on blood pressure and other outcomes ...