1. Neo-digit functional reconstruction of mutilating hand injury using transplantation of multiple composite tissue flaps.

    Medicine (Baltimore) 95(27):e4179 (2016) PMID 27399142

    Functional reconstruction of mutilating hand injuries poses a challenge to the surgeon. We present our experience with use of multiple composite tissue flaps transplant for functional reconstruction of hand in patients with mutilating hand injuries. The associated merits and demerits of these su...
  2. [DECOMPRESSION AND DIVERTING EFFECTS OF VASCULAR ANASTOMOSIS BASED ON DIGITAL ARTERIAL ARCH BRANCH IN REPLANTATION OF FREE FINGER-PULP].

    Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Jo... 30(2):211 (2016) PMID 27276817

    To investigate the decompression and diverting effects of vascular anastomosis based on the digital arterial arch branch in replantation of free finger-pulp in distal phalanges. A retrospective analysis was performed on the clinical data of 12 patients (12 fingers) who underwent free finger-pulp...
  3. Brain-derived neurotrophic factor modulates immune reaction in mice with peripheral nerve xenotransplantation.

    Neuropsychiatric Disease and Treatment 12:685 (2016) PMID 27099498 PMCID PMC4820192

    Brain-derived neurotrophic factor (BDNF) has been demonstrated to play an important role in survival, differentiation, and neurite outgrowth for many types of neurons. This study was designed to identify the role of BDNF during peripheral nerve xenotransplantation. A peripheral nerve xenotranspl...
  4. A novel fluorescent retrograde neural tracer: cholera toxin B conjugated carbon dots.

    Nanoscale 7(38):15635 (2015) PMID 26285001

    The retrograde neuroanatomical tracing method is a key technique to study the complex interconnections of the nervous system. Traditional tracers have several drawbacks, including time-consuming immunohistochemical or immunofluorescent staining procedures, rapid fluorescence quenching and low fl...
  5. Peripheral nerve mutilation through biodegradable conduit small gap tubulisation: a multicentre randomised trial

    The Lancet 386:S40 (2015)

    Background Although peripheral nerve injury is repaired by ingenious epineurial neurorrhaphy, functional recovery is usually not satisfactory and is hindered by many factors, including the misconnections of sensory and motor nerve fibres, difficulties in target organ reinnerv...
  6. Experimental study of the functional reserve of median nerve in rats.

    International journal of clinical and experimen... 8(9):16015 (2015) PMID 26629106 PMCID PMC4658995

    To study the functional changes of median nerve after removing a certain bundle of it and to explore the functional reserve of median nerves. 220 three-month old SD rats were randomly divided into experimental groups and sham groups. And the experimental group was further divided as 1/8 group, 1...
  7. The crosslink enhanced emission (CEE) in non-conjugated polymer dots: from the photoluminescence mechanism to the cellular uptake mechanism and internalization.

    Chemical Communications 50(89):13845 (2014) PMID 25259373

    The crosslink enhanced emission (CEE) in a new type of non-conjugated polymer dots (PDs) is proved. The enhanced PL originates from the decreased vibration and rotation of amino-based chromophores. Furthermore, the cellular uptake mechanism and internalization of PDs were investigated in detail.
  8. Bowel dysfunction in spinal cord injury: current perspectives.

    Cell Biochemistry and Biophysics 69(3):385 (2014) PMID 24549854

    Permanent disruptions of gastrointestinal function are very common sequel of spinal cord injury (SCI). When motor and sensory nervous integrity are severely affected, neurogenic gastrointestinal dysfunction is an inevitable consequence. Autonomic nervous system miss function has significantly di...
  9. Peripheral nerve injuries treatment: a systematic review.

    Cell Biochemistry and Biophysics 68(3):449 (2014) PMID 24037713

    Patients with peripheral nerve injuries, especially severe injury, often face poor nerve regeneration and incompletely functional recovery, even after surgical nerve repair. Current researches have extensively focused on the new approaches for the treatment of peripheral nerve injuries. This rev...
  10. Cell debris self-immobilized thermophilic lipase: a biocatalyst for synthesizing aliphatic polyesters.

    Applied Biochemistry and Biotechnology 170(2):399 (2013) PMID 23536248

    The paper explored the catalytic activity of a cell debris self-immobilized thermophilic lipase for polyester synthesis, using the ring-opening polymerization of ε-caprolactone as model. Effects of biocatalyst concentration, temperature, and reaction medium on monomer conversion and product mole...
  11. Biodegradable conduit small gap tubulization for peripheral nerve mutilation: a substitute for traditional epineurial neurorrhaphy.

    International journal of medical sciences 10(2):171 (2013) PMID 23329889 PMCID PMC3547215

    Nerve regeneration and re-innervation are usually difficult after peripheral nerve injury. Epineurium neurorrhaphy to recover the nerve continuity is the traditional choice of peripheral nerve mutilation without nerve defects, whereas the functional recovery remains quite unsatisfactory. Based o...
  12. Determination of lower limb microvasculature by intrafemoral arterial injection using computed tomography-assisted angiography.

    Aesthetic Plastic Surgery 36(6):1376 (2012) PMID 22949156

    Computed tomography-assisted angiography (CTA) for lower limb vasculature can identify perforators only as small as 1 mm in diameter. The technique does not clearly show the microvascularity in subdermal layers of the skin. This study investigated a novel method of CTA using intrafemoral injecti...
  13. Differentiation of endogenous neural stem cells in adult versus neonatal rats after brachial plexus root avulsion injury.

    Neural Regeneration Research 7(23):1786 (2012) PMID 25624802 PMCID PMC4302527

    An experimental model of brachial plexus root avulsion injury of cervical dorsal C5-6 was established in adult and neonatal rats. Real-time PCR showed that the levels of brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3 in adult rats increased rapidly 1 day after brachial...
  14. A crucial role of IL-17 and IFN-γ during acute rejection of peripheral nerve xenotransplantation in mice.

    PLoS ONE 7(3):e34419 (2012) PMID 22479627 PMCID PMC3316676

    Nerve injuries causing segmental loss require nerve grafting. However, autografts and allografts have limitations for clinical use. Peripheral nerve xenotransplantation has become an area of great interest in clinical surgery research as an alternative graft strategy. However, xenotransplant rej...
  15. The homodigital neurovascular antegrade island flap for fingertip reconstruction in children.

    Acta Orthopaedica Belgica 77(5):598 (2011) PMID 22187833

    We describe a homodigital neurovascular island flap for fingertip reconstruction in children and review the appearance and function of the reconstructed fingertips. Eleven children, with a mean age of 4 years (range: 2-7),who had sustained a fingertip injury with total or subtotal pulp loss were...
  16. Differentiation between the motor and sensory fascicles of the peripheral nerves from adult rats using annexin V-CdTe-conjugated polymer.

    Neurology India 59(3):333 (2011) PMID 21743158

    Until now, no method has been available to rapidly differentiate between the motor and sensory nerve fascicles introperatively. To establish a method to rapidly differentiate between the sensory and motor fascicles in the peripheral nerves. Annexin V-CdTe-conjugated polymer was used to stain the...
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  17. Diffuse scalp malignant peripheral nerve sheath tumor with intracranial extension in a patient with neurofibromatosis type 1.

    Journal of Clinical Neuroscience 17(11):1443 (2010) PMID 20655235

    We describe a rare scalp malignant peripheral nerve sheath tumor (MPNST) with cranial destruction and intracranial extension in a 52-year-old male with neurofibromatosis type 1 (NF1). The scalp tumor measured 22cm×18cm, with local surface ulceration. Skin examination revealed many café-au-lait s...
  18. [Lateral columella base-labrum transposition flap for repairing mild unilateral eclabium deformity of upper lip].

    Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Jo... 23(3):319 (2009) PMID 19366144

    To study the feasibility of repairing the mild unilateral eclabium deformity of the upper lip with the lateral columella base-labrum transposition flap. From March 2006 to March 2008, 8 patients with mild unilateral eclabium of the upper lip were repaired with the lateral columella base-labrum t...
  19. [Effect of velvet antler polypeptide on peripheral nerve regeneration].

    Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Jo... 22(12):1458 (2008) PMID 19137890

    To investigate the velvet antler polypeptide (VAP) on sciatic nerve regeneration in rats through local administration and VAP-PLGA compound membrane. The 3, 15 mg/g of VAP-PLGA compound membrane were prepared by compounding VAP and PLGA, respectively. Seventy-two Wistar rats, male or female, age...
  20. [Spinal pathologic changes and axonal regeneration after brachial plexus root anastomosis in rats].

    Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Jo... 22(9):1077 (2008) PMID 18822732

    To evaluate the feasibility of direct anastomosis in the rat model of the brachial plexus extravertebral foramen nerve root division of C5-7. Methods Forty-eight SD rats (male or female) aging 4-6 months and weighing 250-300 g were selected to make the model of extravertebral foramen nerve root ...