1. Genetic and epigenetic architecture of sex-biased expression in the jewel wasps Nasonia vitripennis and giraulti.

    PNAS 112(27):E3545 (2015) PMID 26100871 PMCID PMC4500217

    There is extraordinary diversity in sexual dimorphism (SD) among animals, but little is known about its epigenetic basis. To study the epigenetic architecture of SD in a haplodiploid system, we performed RNA-seq and whole-genome bisulfite sequencing of adult females and males from two closely re...
  2. A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor.

    Current Biology 25(5):613 (2015) PMID 25660540

    Gall-forming arthropods are highly specialized herbivores that, in combination with their hosts, produce extended phenotypes with unique morphologies [1]. Many are economically important, and others have improved our understanding of ecology and adaptive radiation [2]. However, the mechanisms th...
  3. Nasonia vitripennis venom causes targeted gene expression changes in its fly host.

    Molecular Ecology 23(23):5918 (2014) PMID 25319487

    Parasitoid wasps are diverse and ecologically important insects that use venom to modify their host's metabolism for the benefit of the parasitoid's offspring. Thus, the effects of venom can be considered an 'extended phenotype' of the wasp. The model parasitoid wasp Nasonia vitripennis has appr...
  4. Nasonia vitripennis venom causes targeted gene expression changes in its fly host.

    Molecular Ecology 23(23):5918 (2014) PMID 25319487

    Parasitoid wasps are diverse and ecologically important insects that use venom to modify their host's metabolism for the benefit of the parasitoid's offspring. Thus, the effects of venom can be considered an 'extended phenotype' of the wasp. The model parasitoid wasp Nasonia vitripennis has appr...
  5. Nasonia vitripennis venom causes targeted gene expression changes in its fly host.

    Molecular Ecology 23(23):5918 (2014) PMID 25319487

    Parasitoid wasps are diverse and ecologically important insects that use venom to modify their host's metabolism for the benefit of the parasitoid's offspring. Thus, the effects of venom can be considered an 'extended phenotype' of the wasp. The model parasitoid wasp Nasonia vitripennis has appr...
  6. Nasonia vitripennis venom causes targeted gene expression changes in its fly host.

    Molecular Ecology 23(23):5918 (2014) PMID 25319487

    Parasitoid wasps are diverse and ecologically important insects that use venom to modify their host's metabolism for the benefit of the parasitoid's offspring. Thus, the effects of venom can be considered an 'extended phenotype' of the wasp. The model parasitoid wasp Nasonia vitripennis has appr...
  7. A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor

    Current Biology (2014)

    • The plant galling Mayetiola destructor genome is replete with effector genes • The SSGP-71 effector gene family is the largest known arthropod gene family. ...
  8. Dobzhansky-muller and wolbachia-induced incompatibilities in a diploid genetic system.

    PLoS ONE 9(4):e95488 (2014) PMID 24759973 PMCID PMC3997523

    Genetic incompatibilities are supposed to play an important role in speciation. A general (theoretical) problem is to explain the persistence of genetic diversity after secondary contact. Previous theoretical work has pointed out that Dobzhansky-Muller incompatibilities (DMI) are not stable in t...
  9. Dobzhansky-muller and wolbachia-induced incompatibilities in a diploid genetic system.

    PLoS ONE 9(4):e95488 (2014) PMID 24759973 PMCID PMC3997523

    Genetic incompatibilities are supposed to play an important role in speciation. A general (theoretical) problem is to explain the persistence of genetic diversity after secondary contact. Previous theoretical work has pointed out that Dobzhansky-Muller incompatibilities (DMI) are not stable in t...
  10. Dobzhansky-muller and wolbachia-induced incompatibilities in a diploid genetic system.

    PLoS ONE 9(4):e95488 (2014) PMID 24759973 PMCID PMC3997523

    Genetic incompatibilities are supposed to play an important role in speciation. A general (theoretical) problem is to explain the persistence of genetic diversity after secondary contact. Previous theoretical work has pointed out that Dobzhansky-Muller incompatibilities (DMI) are not stable in t...
  11. Fine-scale mapping of the Nasonia genome to chromosomes using a high-density genotyping microarray.

    G3: Genes, Genomes, Genetics 3(2):205 (2013) PMID 23390597 PMCID PMC3564981

    Nasonia, a genus of four closely related parasitoid insect species, is a model system for genetic research. Their haplodiploid genetics (haploid males and diploid females) and interfertile species are advantageous for the genetic analysis of complex traits and the genetic basis of species differ...
  12. Fine-scale mapping of the Nasonia genome to chromosomes using a high-density genotyping microarray.

    G3: Genes, Genomes, Genetics 3(2):205 (2013) PMID 23390597 PMCID PMC3564981

    Nasonia, a genus of four closely related parasitoid insect species, is a model system for genetic research. Their haplodiploid genetics (haploid males and diploid females) and interfertile species are advantageous for the genetic analysis of complex traits and the genetic basis of species differ...
  13. Obligate mutualism within a host drives the extreme specialization of a fig wasp genome.

    Genome biology 14(12):R141 (2013) PMID 24359812 PMCID PMC4053974

    Fig pollinating wasps form obligate symbioses with their fig hosts. This mutualism arose approximately 75 million years ago. Unlike many other intimate symbioses, which involve vertical transmission of symbionts to host offspring, female fig wasps fly great distances to transfer horizontally bet...
  14. Characterizing the infection-induced transcriptome of Nasonia vitripennis reveals a preponderance of taxonomically-restricted immune genes.

    PLoS ONE 8(12):e83984 (2013) PMID 24386321 PMCID PMC3873987

    The innate immune system in insects consists of a conserved core signaling network and rapidly diversifying effector and recognition components, often containing a high proportion of taxonomically-restricted genes. In the absence of functional annotation, genes encoding immune system proteins ca...
  15. Characterizing the infection-induced transcriptome of Nasonia vitripennis reveals a preponderance of taxonomically-restricted immune genes.

    PLoS ONE 8(12):e83984 (2013) PMID 24386321 PMCID PMC3873987

    The innate immune system in insects consists of a conserved core signaling network and rapidly diversifying effector and recognition components, often containing a high proportion of taxonomically-restricted genes. In the absence of functional annotation, genes encoding immune system proteins ca...
  16. Characterization of an ancient lepidopteran lateral gene transfer.

    PLoS ONE 8(3):e59262 (2013) PMID 23533610 PMCID PMC3606386

    Bacteria to eukaryote lateral gene transfers (LGT) are an important potential source of material for the evolution of novel genetic traits. The explosion in the number of newly sequenced genomes provides opportunities to identify and characterize examples of these lateral gene transfer events, a...
  17. Characterization of an ancient lepidopteran lateral gene transfer.

    PLoS ONE 8(3):e59262 (2013) PMID 23533610 PMCID PMC3606386

    Bacteria to eukaryote lateral gene transfers (LGT) are an important potential source of material for the evolution of novel genetic traits. The explosion in the number of newly sequenced genomes provides opportunities to identify and characterize examples of these lateral gene transfer events, a...
  18. Function and evolution of DNA methylation in Nasonia vitripennis.

    PLoS Genetics 9(10):e1003872 (2013) PMID 24130511 PMCID PMC3794928

    The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns repo...
  19. Function and evolution of DNA methylation in Nasonia vitripennis.

    PLoS Genetics 9(10):e1003872 (2013) PMID 24130511 PMCID PMC3794928

    The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns repo...
  20. Obligate mutualism within a host drives the extreme specialization of a fig wasp genome.

    Genome biology 14(12):R141 (2013) PMID 24359812 PMCID PMC4053974

    Fig pollinating wasps form obligate symbioses with their fig hosts. This mutualism arose approximately 75 million years ago. Unlike many other intimate symbioses, which involve vertical transmission of symbionts to host offspring, female fig wasps fly great distances to transfer horizontally bet...