1. Circulating lymphocyte subsets in normal adults are variable and can be clustered into subgroups.

    Cytometry Part B 80(5):291 (2011) PMID 21472851

    Flow cytometry is used to monitor lymphocyte subsets in both the clinical and research settings. An understanding of the degree of inter- and intrasubject variability of these populations is critical for data interpretation. Peripheral blood lymphocytes of 18 healthy adults were analyzed on two ...
  2. Analysis of B cell subsets following pancreatic islet cell transplantation in a patient with type 1 diabetes by cytometric fingerprinting.

    Journal of Immunological Methods 363(2):233 (2011) PMID 20933515 PMCID PMC3010186

    Manual gating of bivariate plots remains the most frequently used data analysis method in flow cytometry. However, gating is operator-dependent and cumbersome, particularly with the increasing complexity of modern multicolor immunophenotyping data. A method that can remove operator bias, enable ...
  3. Secondary adrenal insufficiency in an infant after intrathecal triple chemotherapy.

    Pediatric Blood & Cancer 55(2):386 (2010) PMID 20582966

    Intrathecal triple chemotherapy (ITT) with hydrocortisone, methotrexate, and cytarabine is commonly used in treatment of pediatric acute leukemias. While prolonged systemic administration of corticosteroids is known to suppress the hypothalamic-pituitary-adrenal axis, there have been no reports ...
  4. A longitudinal analysis of SLE patients treated with rituximab (anti-CD20): factors associated with B lymphocyte recovery.

    Clinical Immunology 126(3):282 (2008) PMID 18226586

    Identifying factors associated with B lymphocyte depletion and recovery may aid the development of individualized treatment regimens, optimizing therapy for patients with autoimmune disease. In this study, 12 patients with active SLE were monitored at baseline and monthly following treatment wit...
  5. B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates.

    Nature Medicine 13(11):1295 (2007) PMID 17965721

    We found that an induction immunotherapy regimen consisting of rabbit anti-thymocyte globulin (Thymoglobulin) and the monoclonal antibody to CD20 rituximab (Rituxan) promoted long-term islet allograft survival in cynomolgus macaques maintained on rapamycin monotherapy. B lymphocyte reconstitutio...
  6. Adrenocortical tumors and hyperplasias in childhood--etiology, genetics, clinical presentation and therapy.

    Pediatric endocrinology reviews : PER 4(1):32 (2006) PMID 17021581 PMCID PMC1907361

    Adrenocortical tumors are rare in children and are associated with a poor prognosis when malignant. The fund of knowledge regarding etiology, presentation and clinical outcomes remains limited. Evaluation of genetic disorders associated with the development of adrenocortical disorders has allowe...