1. [A case of elderly-onset herpes simplex encephalitis in an 89-year-old woman, who recovered with acyclovir therapy, showed relapse 2 months later, and died].

    Brain and nerve = Shinkei kenkyu no shinpo 64(9):1063 (2012) PMID 22941843

    The number of case reports on elderly-onset herpes simplex encephalitis (HSE) has been increasing. We encountered the case of an 89-year-old woman with HSE, who was probably one of the oldest-onset patients in Japan. She was a bed patient with underlying diseases of old cerebral infarction and c...
  2. Production of multiple extracellular enzyme activities by novel submerged culture of Aspergillus kawachii for ethanol production from raw cassava flour.

    Journal of Industrial Microbiology 39(4):605 (2012) PMID 22072435

    Cassava is a starch-containing root crop that is widely used as a raw material in a variety of industrial applications, most recently in the production of fuel ethanol. In the present study, ethanol production from raw (uncooked) cassava flour by simultaneous saccharification and fermentation (...
  3. Indigestible dextrin is an excellent inducer for α-amylase, α-glucosidase and glucoamylase production in a submerged culture of Aspergillus oryzae.

    Biotechnology Letters 34(2):347 (2012) PMID 22009575

    α-Amylase activities of Aspergillus oryzae grown on dextrin or indigestible dextrin were 7·8 and 27·7 U ml(-1), respectively. Glucoamylase activities of the cultures grown on dextrin or indigestible dextrin were 5·4 and 301 mU ml(-1), respectively. The specific glucoamylase production rate in in...
  4. Indigestible dextrin stimulates glucoamylase production in submerged culture of Aspergillus kawachii.

    Journal of Industrial Microbiology 38(12):1985 (2011) PMID 21618143

    Submerged batch cultures of Aspergillus kawachii grown on indigestible dextrin were investigated for potential improvements in glucoamylase (GA) production. In flask culture, specific GA productivities per dry weight biomass using dextrin and indigestible dextrin were 11.0 and 56.1 mU/mg-DW, res...
  5. Photoinduced molecular reorientation in photoreactive liquid crystalline copolymers in a phase retarder application

    Polymer 52(25):5788 (2011)

    Polymethacrylate copolymers, which have hexamethylene spacer groups terminated with 4-methoxyphenyl-4′-oxycinnamate (MPC) and 4-oxybenzoic acid (BA) in the side chain, were synthesized. Thin films underwent thermally enhanced photoinduced cooperative molecular reorientation using linearly p...
  6. [Clinical characteristics of non-herpetic limbic encephalitis].

    Brain and nerve = Shinkei kenkyu no shinpo 62(8):853 (2010) PMID 20714033

    In Japan,the prevalence of non-herpetic acute limbic encephalitis (NHALE),characterized by a lack of evidence of the herpes simplex virus (HSV) genome or enzyme-linked immunosorbent assay (ELISA) antibody,has shown an upward trend. The causes of NHALE include several anti-neural antibodies relat...
  7. Analysis of enzyme production by submerged culture of Aspergillus oryzae using whole barley.

    Bioscience, Biotechnology, and Biochemistry 73(10):2190 (2009) PMID 19809198

    We have reported on high enzyme production by submerged culture of Aspergillus kawachii using barley with the husk (whole barley). To elucidate the mechanism underlying this high enzyme production, we performed a detailed analysis. Aspergillus oryzae RIB40 was submerged-cultured using whole barl...
  8. Can we predict a prolonged course and intractable cases of herpes simplex encephalitis?

    Internal Medicine (Tokyo, 1992) 48(4):177 (2009) PMID 19218765

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  9. Cerebrospinal fluid levels of cytokines in non-herpetic acute limbic encephalitis: comparison with herpes simplex encephalitis.

    Cytokine 44(1):149 (2008) PMID 18722137

    Recently, non-herpetic acute limbic encephalitis (NHALE) was identified as a new subgroup of limbic encephalitis. The immunological pathophysiology of NHALE is still unclear. We measured the concentrations of interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha), interleukin-2 (I...
  10. Discrimination of antibody to herpes B virus from antibody to herpes simplex virus types 1 and 2 in human and macaque sera.

    Journal of Clinical Microbiology 46(1):56 (2008) PMID 17989200 PMCID PMC2224259

    The antigenic cross-reactive characteristics of herpes B virus and herpes simplex virus (HSV) type 1 (HSV-1) and HSV-2 are responsible for false-positive diagnoses by serological assays in humans and macaques. In the present study, we developed a fluorometric indirect enzyme-linked immunosorbent...
  11. Simultaneous production of glucoamylase and acid-stable alpha-amylase using novel submerged culture of Aspergillus kawachii NBRC4308.

    Journal of Bioscience and Bioengineering 103(2):203 (2007) PMID 17368406

    We developed a novel submerged culture system of Aspergillus kawachii NBRC4308 using barley whose surface is completely or partly covered with husk. The culture supernatant showed a glucoamylase activity of 150.8 U/ml and an acid-stable alpha-amylase activity of 7.7 U/ml brought about by the mai...
  12. [Japanese guidelines for the management of herpes simplex encephalitis; comparison with those from the International Management Herpes Forum].

    Rinsho Shinkeigaku 46(11):955 (2006) PMID 17432231

    Herpes simplex encephalitis (HSE) is still recognized as a severe sporadic encephalitis, although the mortality and morbidity rates have been decreased to 10% and 30%, respectively. This disease is diagnosed using clinical symptoms, CSF, EEG, CT, MRI, and virologic tests such as polymerase chain...
  13. [Tuberculous meningoencephalitis].

    Nihon Naika Gakkai Zasshi 95(7):1251 (2006) PMID 16893016

  14. Invasion assay of Listeria monocytogenes using Vero and Caco-2 cells.

    Journal of Microbiological Methods 66(1):96 (2006) PMID 16410027

    The invasion ability of Listeria monocytogenes into cultured cells has been used to evaluate its pathogenicity. In this study, invasive ability was investigated using Vero and Caco-2 cell lines. The form of invasion showed no morphological differences between both cell lines inoculated with L. m...
  15. [Herpes encephalitis].

    Nippon rinsho. Japanese journal of clinical med... 64 Suppl 3:264 (2006) PMID 16615480

  16. Adult meningism and viral meningitis, 1997-2004: clinical data and cerebrospinal fluid cytokines.

    Internal Medicine (Tokyo, 1992) 45(21):1209 (2006) PMID 17139119

    Although meningism manifesting acute headache has been observed to be associated with common viral and bacterial infections, its definition and pathogenesis have not been clarified. Clinical findings and cerebrospinal fluid (CSF) cytokines in adult patients with meningism were investigated and c...
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  17. Herpes simplex virus type 2 recurrent meningitis (Mollaret's meningitis): a consideration for the recurrent pathogenesis.

    Journal of Infection 51(4):e217 (2005) PMID 16291273

    We report a 44-year-old Japanese woman with herpes simplex virus (HSV) type 2 recurrent meningitis (Mollaret's meningitis). The diagnosis was confirmed by nested polymerase chain reaction in her cerebrospinal fluid, but the patient's conventional HSV antibodies by complement fixation, neutralizi...
  18. Comparison of genomic structures in the serovar 1/2a Listeria monocytogenes isolated from meats and listeriosis patients in Japan.

    Japanese Journal of Infectious Diseases 58(5):289 (2005) PMID 16249623

    Foodborne disease by Listeria monocytogenes, serovar 1/2a has recently been reported in many countries. Although contamination by this bacteria is also known to be gradually spreading among the marketed foods of Japan, there is little information on relation between listeriosis and food contamin...
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  19. Herpes simplex encephalitis presenting with bilateral hippocampal lesions on magnetic resonance imaging, simultaneously complicated by small cell lung carcinoma.

    Internal Medicine (Tokyo, 1992) 44(9):1006 (2005) PMID 16258223

    We report a 75-year-old man who developed herpes simplex encephalitis (HSE), presenting with bilateral hippocampal lesions on magnetic resonance imaging, and this case was simultaneously complicated by small cell lung carcinoma. We identified a new anti-neuronal antibody in the cerebrospinal flu...
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  20. Probable chronic viral encephalitis with microglial nodules in the entire brain: a case report with necropsy.

    Medical Science Monitor 11(5):CS23 (2005) PMID 15874892

    Chronic encephalitis has rarely been seen, probably due to its viral origins, which may produce the disease in healthy or immunocompromised hosts. The etiology and pathophysiology of these types of encephalitis have not yet been clarified. A 63-year-old Japanese woman with underlying multiple my...