1. Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility.

    Molecular Brain 8(1):38 (2015) PMID 26104314 PMCID PMC4477293

    Guanine nucleotide exchange factors (GEFs) activate small GTPases that are involved in several cellular functions. cAMP-guanine nucleotide exchange factor II (cAMP-GEF II) acts as a target for cAMP independently of protein kinase A (PKA) and functions as a GEF for Rap1 and Rap2. Although cAMP-GE...
  2. Importance of tryptophan nitration of carbonic anhydrase III for the morbidity of atopic dermatitis.

    Free Radical Biology and Medicine 73:75 (2014) PMID 24838180

    The nitration of proteins results from the vigorous production of reactive nitrogen species in inflammatory disease. We previously reported the proteomic analysis of nitrated tryptophan residues in in vitro model cells for inflammatory diseases using a 6-nitrotryptophan-specific antibody. In thi...
  3. A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (the AMAZE study).

    World Journal of Biological Psychiatry 15(2):113 (2014) PMID 22540407

    To investigate the efficacy and safety of aripiprazole in Asian patients with manic or mixed episodes associated with bipolar I disorder. Subjects were randomised to aripiprazole (24 mg/day; reduced to 12 mg/day if needed for tolerability; n = 128) or placebo (n = 130) for 3 weeks in this multic...
  4. A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (the AMAZE study).

    World Journal of Biological Psychiatry 15(2):113 (2014) PMID 22540407

    To investigate the efficacy and safety of aripiprazole in Asian patients with manic or mixed episodes associated with bipolar I disorder. Subjects were randomised to aripiprazole (24 mg/day; reduced to 12 mg/day if needed for tolerability; n = 128) or placebo (n = 130) for 3 weeks in this multic...
  5. A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (the AMAZE study).

    World Journal of Biological Psychiatry 15(2):113 (2014) PMID 22540407

    To investigate the efficacy and safety of aripiprazole in Asian patients with manic or mixed episodes associated with bipolar I disorder. Subjects were randomised to aripiprazole (24 mg/day; reduced to 12 mg/day if needed for tolerability; n = 128) or placebo (n = 130) for 3 weeks in this multic...
  6. Presence of Nitrotryptophan-Containing Proteins in the Adult Rat1Skeletal Muscle-PSS236

    Free Radical Biology and Medicine 65:S106 (2013)

  7. PSS216 - Proteomic Analysis for Identification of 6-NO2Trp Containing Proteins in Stroke-Prone Spontaneously Hypertensive Rat, SHRSP

    Free Radical Biology and Medicine 65:S99 (2013)

  8. Presence of Nitrotryptophan-Containing Proteins in the Adult Rat1Skeletal Muscle-PSS236

    Free Radical Biology and Medicine 65:S106 (2013)

  9. PSS99 - Peroxynitrous Acid Mediated Oxidation of Fibronectin Affects Protein Structure and Compromises Endothelial Cell Binding

    Free Radical Biology and Medicine 65:S53 (2013)

  10. Peroxynitrous Acid Mediated Oxidation of Fibronectin Affects Protein Structure and Compromises Endothelial Cell Binding-PSS99

    Free Radical Biology and Medicine 65:S53 (2013)

  11. Proteomic Analysis for Identification of 6-NO2Trp Containing Proteins in Stroke-Prone Spontaneously Hypertensive Rat, SHRSP-PSS216

    Free Radical Biology and Medicine 65:S99 (2013)

  12. Peroxynitrite-mediated damage in the artery wall and its consequences-SESSION 4

    Free Radical Biology and Medicine 65:S6 (2013)

  13. Peroxynitrite-mediated damage in the artery wall and its consequences-SESSION 4

    Free Radical Biology and Medicine 65:S6 (2013)

  14. Identification of nitrotryptophan-containing proteins in the lesional skin of atopic NC/Nga mice

    Journal of Dermatological Science 69(2):e15 (2013)

  15. Identification of nitrotryptophan-containing proteins in the lesional skin of atopic NC/Nga mice

    Journal of Dermatological Science 69(2):e15 (2013)

  16. [Recommendations for ECT Practice, Second Edition].

    Seishin shinkeigaku zasshi = Psychiatria et neu... 115(6):586 (2013) PMID 23944116

  17. [Recommendations for ECT Practice, Second Edition].

    Seishin shinkeigaku zasshi = Psychiatria et neu... 115(6):586 (2013) PMID 23944116

  18. Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice.

    Frontiers in Behavioral Neuroscience 7:17 (2013) PMID 23487260 PMCID PMC3594921

    The habenular complex linking forebrain and midbrain structures is subdivided into the medial (mHb) and the lateral nuclei (lHb). The mHb is characterized by the expression of specific nicotinic acetylcholine receptor isoforms and the release of acetylcholine to the interpeduncular nucleus (IPN)...
  19. Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice.

    Frontiers in Behavioral Neuroscience 7:17 (2013) PMID 23487260 PMCID PMC3594921

    The habenular complex linking forebrain and midbrain structures is subdivided into the medial (mHb) and the lateral nuclei (lHb). The mHb is characterized by the expression of specific nicotinic acetylcholine receptor isoforms and the release of acetylcholine to the interpeduncular nucleus (IPN)...
  20. Proteomic analysis of endogenous nitrotryptophan-containing proteins in rat hippocampus and cerebellum.

    Bioscience Reports 32(6):521 (2012) PMID 22697601 PMCID PMC3475453

    Nitration of tryptophan residues is a novel post-translational modification. In the present study, we examined whether NO2Trp (nitrotryptophan)-containing proteins are produced in the hippocampus and cerebellum of the adult rat under physiological conditions in vivo. Using Western blot analysis ...