1. Stillbirth in China.

    The Lancet 387(10032):1995 (2016) PMID 27203767

  2. [Effects of BDE-209 exposure on differentiation capacity of human embryonic stem cells].

    Wei sheng yan jiu = Journal of hygiene research 45(3):350 (2016) PMID 27459793

    To study the effects of decabrominated biphenyl ether (BDE-209) exposure on differentiation capacity of human embryonic stem cells. Human embryonic stem cell line FY-hES-10 cells were exposed to the concentrations of 0 (solvent control), 1, 10 to 100 nmol/L BDE-209 for 96 h and then were differe...
  3. BDE-209 inhibits pluripotent genes expression and induces apoptosis in human embryonic stem cells.

    Journal of Applied Toxicology 36(5):659 (2016) PMID 26206603

    Decabromodiphenyl ether (BDE-209) has been detected in human serum, semen, placenta, cord blood and milk worldwide. However, little is known regarding the potential effects on the early human embryonic development of BDE-209. In this study, human embryonic stem cell lines FY-hES-10 and FY-hES-26...
  4. Effects of acupuncture on preeclampsia in Chinese women: a pilot prospective cohort study.

    Acupuncture in Medicine 34(2):144 (2016) PMID 26516136

    To investigate the acceptability and feasibility of acupuncture treatment as an adjunct to usual care in Chinese women with preeclampsia. This was a pilot prospective cohort study. Pregnant women with a diagnosis of preeclampsia were offered acupuncture and allocated into groups based on their c...
  5. The role of myeloid differentiation factor 88 on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis.

    Central European Journal of Immunology 41(2):153 (2016) PMID 27536200

    To investigate the role of myeloid differentiation factor 88 (MyD88) on mitochondrial dysfunction of peritoneal leukocytes during polymicrobial sepsis. Polymicrobial peritonitis, a clinically relevant mouse model of sepsis, was generated by cecum ligation and puncture (CLP) in both male C57BL/6J...
  6. Newborn birth weight, length, and head circumference for gestational age in Guangzhou based on the INTERGROWTH-21st standard: a multiyear hospital liveborn cohort study

    The Lancet 386:S48 (2015)

    Background WHO's INTERGROWTH-21st Project published an international standard for newborn size using a rigorous method. We aimed to examine the frequency of small and large birth weight, length, and head circumference for gestational age for live births in Guangzhou, China. ...
  7. The effects of PBDE-209 exposure during pregnancy on placental ET-1 and eNOS expression and the birth weight of offspring.

    International Journal of Developmental Neurosci... 43:86 (2015) PMID 25824818

    Decabrominated diphenyl ether (PBDE-209) is a persistent organic pollutant. Gestational exposure to PBDE-209 can accumulate in pregnant women and fetuses via the placenta and umbilical cord, affecting perinatal outcome. In this study, pregnant Sprague-Dawley (SD) rats were randomly divided into ...
  8. [Multicenter analysis of risk factors and clinical characteristics of shoulder dystocia].

    Zhonghua fu chan ke za zhi 50(1):12 (2015) PMID 25877418

    To explore the risk factors and clinical characteristics of shoulder dystocia. The data of 44 580 single pregnancy and full-term head delivery were colleceted in the Third Affiliated Hospital of Guangzhou Medical University, Nanfang Hospital, Shenzhen Nanshan Hospital, Peking University Shenzhen...
  9. Importance of Toll-like receptor 2 in mitochondrial dysfunction during polymicrobial sepsis.

    Anesthesiology 121(6):1236 (2014) PMID 25272245 PMCID PMC4237710

    Toll-like receptor 2 (TLR2) contributes to sepsis pathogenesis such as deleterious systemic inflammation, cardiac dysfunction, and high mortality in animal studies. Mitochondrial dysfunction is a key molecular event that is associated with organ injury in sepsis. The role of TLR2 in sepsis-induc...
  10. [Prevalence of syphilis during pregnancy and risk factors for maternal and perinatal infections: a 2009-2013 survey].

    Nan fang yi ke da xue xue bao = Journal of Sout... 34(1):144 (2014) PMID 24463138

    To analyze the risk factors for maternal and perinatal syphilis infections in Guangzhou. We collected the data of pregnant women with perinatal syphilis infections from the Obstetrics Critical Care Center, Third Affiliated Hospital of Guangzhou Medical University during the period from January, ...
  11. Maternal and perinatal outcome in cases of fulminant viral hepatitis in late pregnancy.

    International Journal of Gynecology & Obstetrics 119(2):145 (2012) PMID 22947378

    To investigate maternal and perinatal outcomes in cases of fulminant viral hepatitis in late pregnancy (FVHILP). A multicenter retrospective study was conducted. The records of 40 patients with FVHILP were retrieved from 3 hospitals in China. To analyze the influence of mode of delivery on mater...
  12. The PBDE-209 exposure during pregnancy and lactation impairs immune function in rats.

    Mediators of Inflammation 2012:692467 (2012) PMID 22619485 PMCID PMC3349269

    In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of ...
  13. Analysis of prognosis-associated factors in fulminant viral hepatitis during pregnancy in China.

    International Journal of Gynecology & Obstetrics 114(3):242 (2011) PMID 21752374

    To analyze factors contributing to the prognosis of patients with fulminant viral hepatitis in pregnancy (FVHP). A retrospective study was conducted among 90 patients with FVHP who were admitted between January 1994 and August 2008 in 9 Chinese hospitals with expertise in the treatment of FVHP. ...
  14. Tissue distribution of decabrominated diphenyl ether (BDE-209) and its metabolites in sucking rat pups after prenatal and/or postnatal exposure.

    Toxicology 283(1):49 (2011) PMID 21345361

    Growing evidence has shown that decabromodiphenyl ether (BDE-209) can disrupt thyroid hormones and induce neurological and developmental effects, especially for the fetuses and neonates after prenatal or postnatal exposure. The present study was carried out to examine the effects of in utero and...
  15. Response to the Letter from Biesemeier et al.

    Toxicology 287(1):162 (2011)

  16. Characterization of maternal transfer of decabromodiphenyl ether (BDE-209) administered to pregnant Sprague-Dawley rats.

    Reproductive Toxicology 31(1):106 (2011) PMID 20851178

    To evaluate maternal transfer of decabromodiphenyl ether (BDE-209), Sprague-Dawley rats were given daily oral doses of 5 ╬╝mol/kgb.w. BDE-209 in peanut oil from gestation day (GD) 7 to postpartum day (PD) 4. BDE-209 was increased temporally in maternal blood, placenta, fetuses and neonates. Furth...
  17. Role of brominated diphenly ether-209 in the differentiation of neural stem cells in vitro.

    International Journal of Developmental Neurosci... 28(6):497 (2010) PMID 20600791

    Brominated diphenly ether-209 (BDE-209, decaBDE) is among the most common flame retardants. In a previous study, it was confirmed that exposure to BDE-209 can decrease learning and memory in mice. However, it is still unknown whether BDE-209 has an effect on cultured neural stem cells (NSCs). To...
  18. Protective effect of N-acetylcysteine against BDE-209-induced neurotoxicity in primary cultured neonatal rat hippocampal neurons in vitro.

    International Journal of Developmental Neurosci... 28(6):521 (2010) PMID 20546880

    Globally, brominated diphenyl ether-209 (BDE-209) is the most widely used polybrominated diphenyl ether (PBDEs). It has been reported that BDE-209 induces developmental neurotoxicity in vivo. The purpose of this study was to use an antioxidant, N-acetylcysteine (NAC), as an antidote for the neur...
  19. Assessment of the neurotoxic mechanisms of decabrominated diphenyl ether (PBDE-209) in primary cultured neonatal rat hippocampal neurons includes alterations in second messenger signaling and oxidative stress.

    Toxicology Letters 192(3):431 (2010) PMID 19948212

    2',2',3',3',4',4',5',5',6',6',-decabrominated diphenyl ether (PBDE-209) is the most widely used polybrominated diphenyl ethers (PBDEs) globally. Some animal experiments have found that PBDE-209 caused developmental neurotoxicity. But detailed mechanisms are less well understood. Our experiments ...
  20. Polybrominated diphenyl ethers in South China maternal and fetal blood and breast milk.

    Environmental Pollution 144(3):1024 (2006) PMID 16564120

    Twenty-one-paired human fetal and maternal serum and 27 breast milk samples at South China were analyzed for concentrations of polybrominated diphenyl ethers (PBDEs). Seven PBDE congeners (BDE-28, -47, -99, -100, -153, -154, and -183) were quantified using gas chromatography/mass spectrometry (G...