1. PML in a patient without severe lymphocytopenia receiving dimethyl fumarate.

    New England Journal of Medicine 372(15):1474 (2015) PMID 25853764

    Progressive multifocal leukoencephalopathy developed in a 64-year-old woman who was treated with compounded dimethyl fumarate for psoriasis. Lymphocytopenia in this patient was not as severe as in other patients with PML receiving fumaric acid esters.
  2. Clinical and radiological heterogeneity in aneurysmal sub-arachnoid haemorrhage according to risk-factor profile.

    International Journal of Stroke 9(8):1052 (2014) PMID 24773598

    Risk factors for aneurysmal sub-arachnoid haemorrhage can be divided into environmental and inherited factors; the latter being presumed more important in young patients. We explored in young sub-arachnoid haemorrhage patients whether risk-factor profiles influence clinical and radiological char...
  3. Clinical and radiological heterogeneity in aneurysmal sub-arachnoid haemorrhage according to risk-factor profile.

    International Journal of Stroke 9(8):1052 (2014) PMID 24773598

    Risk factors for aneurysmal sub-arachnoid haemorrhage can be divided into environmental and inherited factors; the latter being presumed more important in young patients. We explored in young sub-arachnoid haemorrhage patients whether risk-factor profiles influence clinical and radiological char...
  4. Risk of cardiovascular events and death in the life after aneurysmal subarachnoid haemorrhage: a nationwide study.

    International Journal of Stroke 9(8):1090 (2014) PMID 22973950

    The increased mortality rates of survivors of aneurysmal subarachnoid haemorrhage have been attributed to an increased risk of cardiovascular events in a registry study in Sweden. Swedish registries have however not been validated for subarachnoid haemorrhage and Scandinavian incidences of cardi...
  5. Clinical and radiological heterogeneity in aneurysmal sub-arachnoid haemorrhage according to risk-factor profile.

    International Journal of Stroke 9(8):1052 (2014) PMID 24773598

    Risk factors for aneurysmal sub-arachnoid haemorrhage can be divided into environmental and inherited factors; the latter being presumed more important in young patients. We explored in young sub-arachnoid haemorrhage patients whether risk-factor profiles influence clinical and radiological char...
  6. Risk of cardiovascular events and death in the life after aneurysmal subarachnoid haemorrhage: a nationwide study.

    International Journal of Stroke 9(8):1090 (2014) PMID 22973950

    The increased mortality rates of survivors of aneurysmal subarachnoid haemorrhage have been attributed to an increased risk of cardiovascular events in a registry study in Sweden. Swedish registries have however not been validated for subarachnoid haemorrhage and Scandinavian incidences of cardi...
  7. Risk of cardiovascular events and death in the life after aneurysmal subarachnoid haemorrhage: a nationwide study.

    International Journal of Stroke 9(8):1090 (2014) PMID 22973950

    The increased mortality rates of survivors of aneurysmal subarachnoid haemorrhage have been attributed to an increased risk of cardiovascular events in a registry study in Sweden. Swedish registries have however not been validated for subarachnoid haemorrhage and Scandinavian incidences of cardi...
  8. Long-term outcome after aneurysmal subarachnoid hemorrhage-risks of vascular events, death from cancer and all-cause death.

    Journal of Neurology 261(2):309 (2014) PMID 24276522

    Smoking and hypertension are risk factors for aneurysmal subarachnoid hemorrhage (aSAH), but also for other cardiovascular diseases and cancer. Few prospective data are available on the very long term risks of vascular diseases and vascular, cancer-related and overall death after aSAH. We determ...
  9. Long-term outcome after aneurysmal subarachnoid hemorrhage-risks of vascular events, death from cancer and all-cause death.

    Journal of Neurology 261(2):309 (2014) PMID 24276522

    Smoking and hypertension are risk factors for aneurysmal subarachnoid hemorrhage (aSAH), but also for other cardiovascular diseases and cancer. Few prospective data are available on the very long term risks of vascular diseases and vascular, cancer-related and overall death after aSAH. We determ...
  10. Age- and gender-specific time trend in risk of death of patients admitted with aneurysmal subarachnoid hemorrhage in the Netherlands.

    International Journal of Stroke 8 Suppl A100:90 (2013) PMID 23489971

    In a meta-analysis of population-based studies, case-fatality rates of subarachnoid hemorrhage have decreased worldwide by 17% between 1973 and 2002. However, age- and gender-specific decreases could not be determined. Because >10% of patients with subarachnoid hemorrhage die before reaching the...
  11. Age- and gender-specific time trend in risk of death of patients admitted with aneurysmal subarachnoid hemorrhage in the Netherlands.

    International Journal of Stroke 8 Suppl A100:90 (2013) PMID 23489971

    In a meta-analysis of population-based studies, case-fatality rates of subarachnoid hemorrhage have decreased worldwide by 17% between 1973 and 2002. However, age- and gender-specific decreases could not be determined. Because >10% of patients with subarachnoid hemorrhage die before reaching the...
  12. Additional risk of hypertension and smoking for aneurysms in people with a family history of subarachnoid haemorrhage.

    Journal of Neurology, Neurosurgery & Psychiatry 83(5):541 (2012) PMID 22423116

    Smoking and hypertension increase the risk of aneurismal subarachnoid haemorrhage (SAH) two to threefold whereas a familial predisposition increases the risk sixfold. We assessed the additional risk of smoking and hypertension for the presence of an intracranial aneurysm (IA) in first-degree rel...
  13. Additional risk of hypertension and smoking for aneurysms in people with a family history of subarachnoid haemorrhage.

    Journal of Neurology, Neurosurgery & Psychiatry 83(5):541 (2012) PMID 22423116

    Smoking and hypertension increase the risk of aneurismal subarachnoid haemorrhage (SAH) two to threefold whereas a familial predisposition increases the risk sixfold. We assessed the additional risk of smoking and hypertension for the presence of an intracranial aneurysm (IA) in first-degree rel...
  14. Excess mortality and cardiovascular events in patients surviving subarachnoid hemorrhage: a nationwide study in Sweden.

    Stroke 42(4):902 (2011) PMID 21330628

    Survivors of aneurysmal subarachnoid hemorrhage (SAH) may have an increased risk of cardiovascular events because of shared risk factors. We compared incidences of vascular diseases, vascular death, and all-cause death after SAH with those in the general population. From the Swedish Hospital Dis...
  15. Excess mortality and cardiovascular events in patients surviving subarachnoid hemorrhage: a nationwide study in Sweden.

    Stroke 42(4):902 (2011) PMID 21330628

    Survivors of aneurysmal subarachnoid hemorrhage (SAH) may have an increased risk of cardiovascular events because of shared risk factors. We compared incidences of vascular diseases, vascular death, and all-cause death after SAH with those in the general population. From the Swedish Hospital Dis...
  16. Massive intraventricular haemorrhage from aneurysmal rupture: patient proportions and eligibility for intraventricular fibrinolysis.

    Journal of Neurology 257(3):354 (2010) PMID 19823896 PMCID PMC2837879

    Massive intraventricular haemorrhage (IVH) complicating aneurysmal subarachnoid haemorrhage (SAH) is associated with a poor prognosis. Small observational studies suggest favourable results from fibrinolysis of the intraventricular blood. We performed an observational study on IVH in a large ser...
  17. Massive intraventricular haemorrhage from aneurysmal rupture: patient proportions and eligibility for intraventricular fibrinolysis.

    Journal of Neurology 257(3):354 (2010) PMID 19823896 PMCID PMC2837879

    Massive intraventricular haemorrhage (IVH) complicating aneurysmal subarachnoid haemorrhage (SAH) is associated with a poor prognosis. Small observational studies suggest favourable results from fibrinolysis of the intraventricular blood. We performed an observational study on IVH in a large ser...
  18. Multiple intracerebral haematomas during normal intensity anticoagulation.

    Practical Neurology 10(1):45 (2010) PMID 20130298

  19. Multiple intracerebral haematomas during normal intensity anticoagulation.

    Practical Neurology 10(1):45 (2010) PMID 20130298

  20. Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis.

    The Lancet Neurology 8(7):635 (2009) PMID 19501022

    In a systematic review, published in 1997, we found that the case fatality of aneurysmal subarachnoid haemorrhage (SAH) decreased during the period 1960-95. Because diagnostic and treatment strategies have improved and new studies from previously non-studied regions have been published since 199...