1. Assessment of chlorpyrifos exposure and absorbed daily doses among infants living in an agricultural area of the Province of Jiangsu, China.

    International Archives of Occupational and Envi... 87(7):753 (2014) PMID 24257932

    Chlorpyrifos (CPF) is one of the most widely used organophosphorous pesticides in China. However, few reports on CPF pesticide exposure and body burden of infants at 2 years of age in China are available. The aim of this study was to assess the exposure level and the absorbed daily dose (ADD) of...
  2. [Simulation of urban expansion based on SLEUTH model in Fuxin City, Northeast China].

    Ying yong sheng tai xue bao = The journal of ap... 25(9):2671 (2014) PMID 25757321

    Urban expansion was simulated by SLEUTH model based on the data of Fuxin City, Northeast China in 1997-2013. The optimal parameters of urban expansion were obtained from SLEUTH model calibration, with the diffusion coefficient as 6, breed coefficient as 64, spread coefficient as 44, slope resist...
  3. [Determination of1-bromopropane in the workplace air by GC-FID].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 31(6):467 (2013) PMID 23803550

    To establish a method for determination 1-bromopropane (1-BP) in workplace air by gas chromatography-flame ionization detector (GC-FID). 1-bromopropane in workplace air was collected with activated charcoal tube, then desorbed by carbon disulfide and determined by GC-FID. 1-bromopropane was quan...
  4. Spin/orbital coupling and charge ordering in LaMnO3/SrMnO3superlattice

    Journal of Magnetism and Magnetic Materials 333:8 (2013)

    Coupled spin, orbital and charge ordering in half-doped perovskite La1/2Sr1/2MnO3 (LSMO) superlattice are quantitatively investigated in realspace using the generalized gradient approximation (GGA) plus on-site Coulomb repulsion U (GGA+U) method. It is found that the high spin Mn3+ sit...
  5. Rare syringyl acylated flavonol glycosides from the aerial parts of Leonurus japonicus Houtt.

    Molecules 18(3):2967 (2013) PMID 23459305

    Five new syringyl acylated flavonol glycosides, named leonurusoides A (1), B (2), C (3), D (4), and E (5), together with one known one 6 were obtained from the aerial parts of Leonurus japonicus. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and...
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  6. Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.

    PLoS ONE 8(4):e62164 (2013) PMID 23637989 PMCID PMC3637435

    Despite aggressive research, central nervous system (CNS) disorders, including blood-brain barrier (BBB) injury caused by microbial infection, stroke, abused drugs [e.g., methamphetamine (METH) and nicotine], and other pathogenic insults, remain the world's leading cause of disabilities. In our ...
  7. [Induction of adventitious roots of Echinacea pallida and accumulation of caffeic acid derivatives].

    China Journal of Chinese Materia Medica 37(24):3768 (2012) PMID 23627176

    To investigate the effect of auxins 2,4-D,IAA,IBA,NAA on induction of adventitious roots as well as that of IBA concentrations on the growth of adventitious roots and the accumulation of caffeic acid derivatives, with test-tube seedling leaves Echinacea pallida as the explant, and cultivate adve...
  8. Hyaluronic acid receptor CD44 deficiency is associated with decreased Cryptococcus neoformans brain infection.

    Journal of Biological Chemistry 287(19):15298 (2012) PMID 22418440 PMCID PMC3346080

    Cryptococcus neoformans is a pathogenic yeast that can invade the brain and cause meningoencephalitis. Our previous in vitro studies suggested that the interaction between C. neoformans hyaluronic acid and human brain endothelial CD44 could be the initial step of brain invasion. In this report, ...
  9. Cryptococcus neoformans-derived microvesicles enhance the pathogenesis of fungal brain infection.

    PLoS ONE 7(11):e48570 (2012) PMID 23144903 PMCID PMC3492498

    Cryptococcal meningoencephalitis is the most common fungal disease in the central nervous system. The mechanisms by which Cryptococcus neoformans invades the brain are largely unknown. In this study, we found that C. neoformans-derived microvesicles (CnMVs) can enhance the traversal of the blood...
  10. Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells.

    PLoS ONE 7(4):e35862 (2012) PMID 22536447 PMCID PMC3334993

    IbeA-induced NF-κB signaling through its primary receptor vimentin as well as its co-receptor PSF is required for meningitic E. coli K1 penetration and leukocyte transmigration across the blood-brain barrier (BBB), which are the hallmarks of bacterial meningitis. However, it is unknown how vimen...
  11. Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells.

    Journal of Biomedical Science 19:19 (2012) PMID 22316086 PMCID PMC3308189

    Cryptococcus neoformans has a predilection for central nervous system infection. C. neoformans traversal of the blood brain barrier, composed of human brain microvascular endothelial cells (HBMEC), is the crucial step in brain infection. However, the molecular mechanism of the interaction betwee...
  12. Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3).

    Journal of Biological Chemistry 286(40):34761 (2011) PMID 21693704 PMCID PMC3186382

    Cryptococcus neoformans is a neurotropic fungal pathogen, which provokes the onset of devastating meningoencephalitis. We used human brain microvascular endothelial cells (HBMEC) as the in vitro model to investigate how C. neoformans traverses across the blood-brain barrier. In this study, we pr...
  13. Involvement of IbeA in meningitic Escherichia coli K1-induced polymorphonuclear leukocyte transmigration across brain endothelial cells.

    Brain Pathology 21(4):389 (2011) PMID 21083634

    Transmigration of neutrophil [polymorphonuclear neutrophil (PMN)] across the blood-brain barrier (BBB) is a critical event in the pathogenesis of bacterial meningitis. We have shown that IbeA is able to induce meningitic Escherichia coli invasion of brain microvascular endothelial cells (BMECs),...
  14. [Capillary gas chromatography internal standard method for the determination of urinary 2,5-hexadione].

    Zhonghua lao dong wei sheng zhi ye bing za zhi ... 29(6):456 (2011) PMID 22096865

  15. Involvement of Na(+), K (+)-ATPase and its inhibitors in HuR-mediated cytokine mRNA stabilization in lung epithelial cells.

    Experientia. Basel 68(1):109 (2011) PMID 20614158

    Increasing evidence demonstrates that Na(+), K(+)-ATPase plays an important role in pulmonary inflammation, but the mechanism remains largely unknown. In this study, we used cardiotonic steroids as Na(+), K(+)-ATPase inhibitors to explore the possible involvement of Na(+), K(+)-ATPase in pulmona...
  16. Reticulate evolution: frequent introgressive hybridization among Chinese hares (genus lepus) revealed by analyses of multiple mitochondrial and nuclear DNA loci.

    BMC Evolutionary Biology 11:223 (2011) PMID 21794180 PMCID PMC3155923

    Interspecific hybridization may lead to the introgression of genes and genomes across species barriers and contribute to a reticulate evolutionary pattern and thus taxonomic uncertainties. Since several previous studies have demonstrated that introgressive hybridization has occurred among some s...
  17. Meningitic Escherichia coli K1 penetration and neutrophil transmigration across the blood-brain barrier are modulated by alpha7 nicotinic receptor.

    PLoS ONE 6(9):e25016 (2011) PMID 21966399 PMCID PMC3178609

    Alpha7 nicotinic acetylcholine receptor (nAChR), an essential regulator of inflammation, is abundantly expressed in hippocampal neurons, which are vulnerable to bacterial meningitis. However, it is unknown whether α7 nAChR contributes to the regulation of these events. In this report, an aggrava...
  18. Lactobacillus rhamnosus GG Suppresses Meningitic E. coli K1 Penetration across Human Intestinal Epithelial Cells In Vitro and Protects Neonatal Rats against Experimental Hematogenous Meningitis.

    International Journal of Microbiology 2009:647862 (2009) PMID 20016677 PMCID PMC2775688

    The purpose of this study was to examine prophylactic efficacy of probiotics in neonatal sepsis and meningitis caused by E. coli K1. The potential inhibitory effect of Lactobacillus rhamnosus GG (LGG) on meningitic E. coli K1 infection was examined by using (i) in vitro inhibition assays with E4...
  19. Linoleic and α-linolenic fatty acids affect biomass and secondary metabolite production and nutritive properties ofPanax ginsengadventitious roots cultured in bioreactors

    Biochemical Engineering Journal 47(1):109 (2009)

    The effect of elicitation with linoleic (C18:2) and α-linolenic (C18:3) fatty acids (LLA and α-LNA) was investigated in Panax ginseng C.A. Meyer adventitious roots cultured in 5 l balloon-type bioreactors. Fatty acids were added in culture medium at 0.0, 1.0, 2.5, 5.0, 10.0, an...
  20. Cytogenetic anchoring of radiation hybrid and virtual maps of sheep chromosome X and comparison of X chromosomes in sheep, cattle, and human.

    Chromosome Research 17(4):497 (2009) PMID 19575301

    A comprehensive physical map was generated for Ovis aries chromosome X (OARX) based on a cytogenomics approach. DNA probes were prepared from bacterial artificial chromosome (BAC) clones from the CHORI-243 sheep library and were assigned to G-banded metaphase spreads via fluorescence in-situ hyb...