1. An AU-rich stem-loop structure is a critical feature of the perinuclear localization signal of c-myc mRNA.

    Biochemical Journal 392(Pt 3):475 (2005) PMID 16042622 PMCID PMC1316286

    In eukaryotic cells, several mRNAs including those of c-myc and c-fos are localized to the perinuclear cytoplasm and associated with the cytoskeleton. The localization element of c-myc mRNA is present within its 3'UTR (3'-untranslated region) but the precise nature of this signal has remained un...