1. Cost Analyses in the US and Japan: A Cross-Country Comparative Analysis Applied to the PRONOUNCE Trial in Non-Squamous Non-Small Cell Lung Cancer.

    Advances in Therapy 32(12):1248 (2015) PMID 26650816 PMCID PMC4679782

    Health technology assessment is not required for regulatory submission or approval in either the United States (US) or Japan. This study was designed as a cross-country evaluation of cost analyses conducted in the US and Japan based on the PRONOUNCE phase III lung cancer trial, which compared pe...
  2. Type 2 diabetes mellitus and microvascular complications 1 year after Roux-en-Y gastric bypass: a case-control study.

    Diabetologia 58(7):1443 (2015) PMID 25893730 PMCID PMC4473013

    We aimed to examine the effects of bariatric surgery on microvascular complications in patients with type 2 diabetes using objective measures. Prospective case-control study of 70 obese surgical patients with type 2 diabetes undergoing gastric bypass surgery matched for age, sex and duration of ...
  3. Severe delayed hemolysis associated with regulated parenteral antimalarial drug.

    Emerging Infectious Diseases 21(1):164 (2015) PMID 25531800 PMCID PMC4285266

  4. Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coli.

    PLoS Genetics 10(2):e1004120 (2014) PMID 24586182 PMCID PMC3930520

    Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI) screens can provide insights into the biolog...
  5. ER exit sites are physical and functional core autophagosome biogenesis components.

    Molecular Biology of the Cell 24(18):2918 (2013) PMID 23904270 PMCID PMC3771953

    Autophagy is a central homeostasis and stress response pathway conserved in all eukaryotes. One hallmark of autophagy is the de novo formation of autophagosomes. These double-membrane vesicular structures form around and deliver cargo for degradation by the vacuole/lysosome. Where and how autoph...
  6. Phospholipase C-ΞΆ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection.

    Fertility and Sterility 97(3):742 (2012) PMID 22217962 PMCID PMC3334266

    To evaluate the imaging of cytoplasmic movements in human oocytes as a potential method to monitor the pattern of Ca(2+) oscillations during activation. Test of a laboratory technique. University medical school research laboratory. Donated unfertilized human oocytes from intracytoplasmic sperm i...
  7. MiniArc single-incision sling in the office setting.

    Journal of Minimally Invasive Gynecology 19(3):331 (2012) PMID 22381958

    To report MiniArc single-incision sling efficacy results in the office setting and the feasibility of performing the procedure in the office. Prospective, single-arm, nonrandomized, institutional review board-approved study (Canadian Task Force classification II-2). Three in-office clinical site...
  8. Exploring protein phosphorylation in response to DNA damage using differentially tagged yeast arrays.

    BioTechniques 45(5):581 (2008) PMID 19007343

    Two collections of chromosomally tagged yeast Saccharomyces cerevisiae strains were previously designed to detect protein-protein interactions via the Cross-and-Capture system. Here, we used these strain collections in a different application to screen for proteins that are phosphorylated in res...
  9. Nonsurgical, radiofrequency collagen denaturation for stress urinary incontinence: retrospective 3-year evaluation.

    Expert Review of Medical Devices 4(4):455 (2007) PMID 17605681

    Transurethral radiofrequency collagen denaturation, a nonsurgical treatment for stress urinary incontinence, reduces regional dynamic tissue compliance without causing tissue necrosis or gross tissue shrinkage, unlike transvaginal radiofrequency tissue ablation. This retrospective study evaluate...
  10. The duality of epidermal growth factor receptor (EGFR) signaling and neural stem cell phenotype: cell enhancer or cell transformer?

    Current Stem Cell Research and Therapy 1(3):387 (2006) PMID 18220882

    Recruitment of neural stem cells (NSCs) represents an elegant strategy for replacing adult central nervous system (CNS) cells lost to injury or disease. However, except in the rostral migratory stream to the olfactory bulb, the adult CNS harbors a relatively non permissive environment for motili...
  11. Outbreak of campylobacteriosis following pre-cooked sausage consumption.

    Australian & New Zealand Journal of Public Heal... 29(6):507 (2005) PMID 16366058

    A small outbreak of campylobacteriosis involving three cases was investigated in terms of Campylobacter types present in the suspect food (pre-cooked sausages) and clinical samples from the cases. Foods and faecal samples from people involved in the incident, which occurred in Christchurch, New ...
  12. Renal Medullary Carcinoma and Sickle Cell Trait

    The Journal of Urology 157(4):1349 (1997)