1. [Management of High-Risk Prostate Cancer and Left Ectopic Ureter Inserting into Seminal Vesicle with Ipsilateral Hypoplastic Kidney of a Young Patient : A Case Report].

    Hinyokika kiyo. Acta urologica Japonica 62(6):329 (2016) PMID 27452497

    A 44-year-old male patient visited our hospital with a chief complaint of macroscopic hematuria. Prostate biopsies were performed due to prostate specific antigen (PSA) 11.6 ng/ml, and he was diagnosed with Gleason score 5+4 prostate cancer. Computed tomography showed a left hypoplastic kidney. ...
  2. [Development of promising biomarkers for prostate cancer].

    Nippon rinsho. Japanese journal of clinical med... 74 Suppl 3:191 (2016) PMID 27344727

  3. [Postoperative complications and management after radical prostatectomy].

    Nippon rinsho. Japanese journal of clinical med... 74 Suppl 3:456 (2016) PMID 27344774

  4. Laparoscopic Versus Open Nephroureterectomy in Muscle-Invasive Upper Tract Urothelial Carcinoma: Subanalysis of the Multi-Institutional National Database of the Japanese Urological Association.

    Journal of Endourology 30(5):520 (2016) PMID 26669358

    Open nephroureterectomy (ONU) is the current standard for muscle-invasive upper tract urothelial carcinoma (UTUC) in the European Association of Urology/Japanese Urological Association (JUA) guidelines. In this study, we compared the postsurgical survival of muscle-invasive UTUC patients treated...
  5. Implication of aortic calcification on persistent hypertension after laparoscopic adrenalectomy in patients with primary aldosteronism.

    International Journal of Urology 23(5):412 (2016) PMID 26840556

    To identify risk factors, including aortic calcification, for persistent hypertension in primary aldosteronism patients undergoing laparoscopic adrenalectomy. Between October 2000 and October 2015, we carried out 101 consecutive laparoscopic adrenalectomies for unilateral primary aldosteronism. ...
  6. Diversity in treatment modalities of Stage II/III urothelial cancer in Japan: sub-analysis of the multi-institutional national database of the Japanese Urological Association.

    Japanese Journal of Clinical Oncology 46(5):468 (2016) PMID 26851754

    We aimed to survey treatment modalities for the patients with Stage II/III urothelial cancer in Japan. We used the multi-institutional national database of the Japanese Urological Association from 348 Japanese institutions, in which a total of 3707 patients with muscle-invasive bladder cancer an...
  7. Significance of preoperative butyrylcholinesterase as an independent predictor of biochemical recurrence-free survival in patients with prostate cancer treated with radical prostatectomy.

    International Journal of Clinical Oncology 21(2):379 (2016) PMID 26223693

    Butyrylcholinesterase (BChE) is an alpha-glycoprotein found in the nervous system and liver. Its serum level is reduced in many clinical conditions, such as liver damage, inflammation, injury, infection, malnutrition, and malignant disease. In this study, we analyzed the potential prognostic sig...
  8. Impact of multimodal treatment on prognosis for patients with metastatic upper urinary tract urothelial cancer: Subanalysis of the multi-institutional nationwide case series study of the Japanese Urological Association.

    International Journal of Urology 23(3):224 (2016) PMID 26659912

    To describe the nature of metastatic upper urinary tract urothelial cancer and determine the prognostic predictors or treatment modality associated with all-cause mortality. Within the nationwide case series study of the Japanese Urological Association, consisting of 1509 patients with urinary t...
  9. I-branching N-acetylglucosaminyltransferase regulates prostate cancer invasiveness by enhancing α5β1 integrin signaling.

    Cancer Science 107(3):359 (2016) PMID 26678556 PMCID PMC4814258

    Cell surface carbohydrates are important for cell migration and invasion of prostate cancer (PCa). Accordingly, the I-branching N-acetylglucosaminyltransferase (GCNT2) converts linear i-antigen to I-branching glycan, and its expression is associated with breast cancer progression. In the present...
  10. Core 2 β-1, 6-N-acetylglucosaminyltransferase-1 expression in prostate biopsy specimen is an indicator of prostate cancer aggressiveness.

    Biochemical and Biophysical Research Communicat... 470(1):150 (2016) PMID 26768364

    To avoid over-treatment of early stage prostate cancer (PCa), predictive biomarkers for PCa aggressiveness which can be obtained during pre-treatment evaluation are essential. Core 2 β-1, 6-N-acetylglucosaminyl-transferase-1 (GCNT1) is a key enzyme that forms core 2 branched O-glycans, the expre...
  11. An Open-Label, Randomized Phase II Trial of Personalized Peptide Vaccination in Patients with Bladder Cancer that Progressed after Platinum-Based Chemotherapy.

    Clinical Cancer Research 22(1):54 (2016) PMID 26581246

    The prognosis of platinum-based chemotherapy-resistant metastatic urothelial cancer of the bladder remains poor. Personalized selection of the right peptides for each patient could be a novel approach for a cancer vaccine to boost anticancer immunity. In this randomized, open-label, phase II stu...
  12. Renal Function Outcomes and Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer [corrected].

    PLoS ONE 11(2):e0149544 (2016) PMID 26901860 PMCID PMC4763863

    To assess the effects of urinary diversion on renal function, we retrospectively investigated renal function over 5 years after urinary diversion using a propensity score matching strategy. Between May 1996 and November 2013, 345 consecutive adult patients underwent radical cystectomy and urinar...
  13. [Multimodality therapy for high-risk prostate cancer].

    Nippon rinsho. Japanese journal of clinical med... 74(1):114 (2016) PMID 26793890

    Multimodal approach should be provided for high-risk prostate cancer patients. Androgen deprivation therapy (ADT) is a standard adjunct to radiotherapy for high-risk prostate cancer, but its role around prostatectomy has not been clearly defined. In a well-selected patient group, radical prostat...
  14. Slow Gait Speed and Rapid Renal Function Decline Are Risk Factors for Postoperative Delirium after Urological Surgery.

    PLoS ONE 11(5):e0153961 (2016) PMID 27145178 PMCID PMC4856409

    The aim of this study was to identify risk factors associated with postoperative delirium in patients undergoing urological surgery. We prospectively evaluated pre- and postoperative risk factors for postoperative delirium in consecutive 215 patients who received urological surgery between Augus...
  15. Efficacy and Safety of Silodosin and Dutasteride Combination Therapy in Acute Urinary Retention due to Benign Prostatic Hyperplasia: A Single-Arm Prospective Study.

    BioMed Research International 2016:4975851 (2016) PMID 27195288 PMCID PMC4852328

    This study aimed to assess the efficacy of combination therapy with dutasteride and silodosin in patients with acute urinary retention (AUR) caused by benign prostatic hyperplasia (BPH). Eighty consecutive patients with a first episode of AUR were enrolled in this study. All patients received si...
  16. Correction: Renal Function Outcomes and Risk Factors for Risk Factors for Stage 3B Chronic Kidney Disease after Urinary Diversion in Patients with Muscle Invasive Bladder Cancer.

    PLoS ONE 11(3):e0151742 (2016) PMID 26978781 PMCID PMC4792434

  17. Sequential chemotherapy using gemcitabine + carboplatin followed by gemcitabine + carboplatin + docetaxel for advanced upper-tract urothelial cancer.

    International Journal of Clinical Oncology 20(6):1179 (2015) PMID 26007690

    Retrospective evaluation of the effectiveness and adverse events (AEs) of a sequential chemotherapy regimen using gemcitabine + carboplatin (GCarbo) followed by GCarbo + docetaxel (GCarboD) for advanced upper-tract urothelial carcinoma (UTUC). We treated 56 patients with advanced UTUC. Mean pati...
  18. Impact of smoking on the age at diagnosis of upper tract urothelial carcinoma: Subanalysis of the Japanese Urological Association multi-institutional national database.

    International Journal of Urology 22(11):1023 (2015) PMID 26238570

    To examine the influence of smoking history on the diagnosis and other tumor characteristics of upper tract urothelial carcinoma in Japan. A total of 1509 patients with upper tract urothelial carcinoma who were diagnosed in 2005 from 348 Japanese institutions were registered using the multi-inst...
  19. Prognostic factors of recurrent disease in upper urinary tract urothelial cancer after radical nephroureterectomy: Subanalysis of the multi-institutional national database of the Japanese Urological Association.

    International Journal of Urology 22(11):1013 (2015) PMID 26242807

    To explore predictive factors of disease recurrence after radical nephroureterectomy in patients with upper urinary tract urothelial cancer. A multi-institutional national database promoted by the Japanese Urological Association including 293 institutions and 1172 patients was used for the prese...
  20. Reassessment of the risk factors for biochemical recurrence in D'Amico intermediate-risk prostate cancer treated using radical prostatectomy.

    International Journal of Urology 22(11):1029 (2015) PMID 26290306

    To assess the risk factors for biochemical recurrence in D'Amico intermediate-risk prostate cancer patients treated using radical prostatectomy. We retrospectively reviewed the medical records of 1268 men with prostate cancer treated using radical prostatectomy without neoadjuvant therapy. The a...