1. Effects of biological age on the associations of blood pressure with cardiovascular and non-cardiovascular mortality in old age: A population-based study.

    International Journal of Cardiology 220:508 (2016) PMID 27390978

    Whether chronological or biological age may play a role in the association between blood pressure and cause-specific mortality in old age is unclear. We seek to investigate the associations of blood pressure with all-cause, cardiovascular, and non-cardiovascular mortality among older people and ...
  2. Defeating Alzheimer's disease and other dementias: a priority for European science and society.

    The Lancet Neurology 15(5):455 (2016) PMID 26987701

  3. The economic burden of mental disorders in China, 2005-2013: implications for health policy.

    BMC Psychiatry 16(1):137 (2016) PMID 27169936 PMCID PMC4864926

    Mental disorders represent a major contributor to disease burden worldwide. We sought to quantify the national economic burden of mental disorders in China. We used a prevalence-based, bottom-up approach to estimate the economic costs of mental disorders in 2005-2013 in China. Prevalence data we...
  4. A Risk Score for the Prediction of Neurocognitive Disorders among Community-Dwelling Chinese Older Adults.

    Dementia and Geriatric Cognitive Disorders 41(5-6):348 (2016) PMID 27433801

    Several risk scores have been developed for predicting cognitive impairment and dementia, but none have been validated in Asian samples. We aimed to produce a risk score that best predicts incident neurocognitive disorder (NCD) among Chinese elderly and to validate this score against the modifie...
  5. Interactive effects of diabetes and impaired kidney function on cognitive performance in old age: a population-based study.

    BMC Geriatrics 16(1):7 (2016) PMID 26753625 PMCID PMC4710025

    The interactive effect between diabetes and impaired kidney function on cognitive impairment in older adults has not yet been reported. The aim of this study was to investigate the association of diabetes and impaired kidney function with cognitive impairment among Chinese older people living in...
  6. Use of medications and functional dependence among Chinese older adults in a rural community: A population-based study.

    Geriatrics and Gerontology International 15(12):1242 (2015) PMID 25598446

    To investigate the associations between medication use and functional dependence in Chinese older people living in a rural community. The cross-sectional study included 1538 participants (age ≥60 years, 59.1% women) in the Confucius Hometown Aging Project in Shandong, China. In June 2010 to July...
  7. The Confucius Hometown Aging Project: a community-based study of ageing and health in a rural area

    The Lancet 386:S57 (2015)

    Background Vascular risk factors (eg, smoking, hypertension, and diabetes) are associated with cognitive and physical dysfunction in old age. We hypothesised that atherosclerotic process plays a central part in linking vascular risk factors and disorders to cognitive and phys...
  8. Trends in disability in activities of daily living among Chinese older adults, 1997-2006: the China Health and Nutrition Survey.

    Journals of Gerontology Series A: Biological Sc... 70(6):739 (2015) PMID 25414515 PMCID PMC4506321

    A decline in prevalence of late-life disability in activities of daily living (ADLs) has been reported in Western countries. We investigate the time trend of disability in basic ADLs among Chinese older people in 1997-2006, and explore the potential contribution of cardiometabolic diseases to th...
  9. A major role for cardiovascular burden in age-related cognitive decline.

    Nature Reviews Cardiology 12(5):267 (2015) PMID 25583619

    The incidence of dementia and cardiovascular disease (CVD) increases with age. Current evidence supports the role for both atherosclerosis and arteriosclerosis as a common pathophysiological ground for the heart-brain connection in ageing. Cognitive decline and CVDs share many vascular risk fact...
  10. Effects of vascular risk factors and APOE ε4 on white matter integrity and cognitive decline.

    Neurology 84(11):1128 (2015) PMID 25672924 PMCID PMC4371409

    To investigate the effects of vascular risk factors and APOE status on white matter microstructure, and subsequent cognitive decline among older people. This study included 241 participants (age 60 years and older) from the population-based Swedish National Study on Aging and Care in Kungsholmen...
  11. Cohort Effects in the Prevalence and Survival of People with Dementia in a Rural Area in Northern Sweden.

    Journal of Alzheimer's Disease 50(2):387 (2015) PMID 26639970

    Recent studies suggest that trends in cardiovascular risk may result in a decrease in age-specific prevalence of dementia. Studies in rural areas are rare. To study cohort effects in dementia prevalence and survival of people with dementia in a Swedish rural area. Participants were from the 1995...
  12. Prevalence and Patterns of Chronic Disease Pairs and Multimorbidity among Older Chinese Adults Living in a Rural Area.

    PLoS ONE 10(9):e0138521 (2015) PMID 26394368 PMCID PMC4578976

    The burden of chronic diseases in China is substantial now. Data on patterns of chronic diseases and multimorbidity among older adults, especially among those living in rural areas, are sparse. We aim to investigate the prevalence and patterns of chronic disease pairs and multimorbidity in elder...
  13. Prevalence, pharmacological treatment, and control of cardiometabolic risk factors among older people in central Stockholm: a population-based study.

    PLoS ONE 10(3):e0119582 (2015) PMID 25799502 PMCID PMC4370718

    Cardiometabolic risk factors and related cardiovascular diseases represent major threats to healthy aging. We aimed to estimate distribution, pharmacological treatment, and control of main cardiometabolic risk factors among older people. This population-based study included 3363 participants (ag...
  14. Patterns of cardiovascular drugs prescribed for an elderly Swedish population.

    International Journal of Cardiology 177(3):1091 (2014) PMID 25449520

  15. Walking speed, processing speed, and dementia: a population-based longitudinal study.

    Journals of Gerontology Series A: Biological Sc... 69(12):1503 (2014) PMID 24706441

    Slow walking speed has been shown to predict dementia. We investigated the relation of walking speed, processing speed, and their changes over time to dementia among older adults. This study included 2,938 participants (age 60+ years) in the population-based Swedish National study on Aging and C...
  16. Highly prevalent and poorly controlled cardiovascular risk factors among Chinese elderly people living in the rural community.

    European Journal of Preventive Cardiology 21(10):1267 (2014) PMID 23598595

    The epidemiological scenario of cardiovascular risk factors (CRFs) among elderly people in rural China is unclear. We seek to describe the distribution, burden and management of major CRFs among older Chinese people living in the rural community. This cross-sectional study included 1538 particip...
  17. Vascular risk factor burden, atherosclerosis, and functional dependence in old age: a population-based study.

    International Journal of Behavioral Medicine 21(4):597 (2014) PMID 24057410

    Vascular risk factors such as hypertension and obesity have been associated with physical limitations among older adults. The purpose of this study is to examine whether individual and aggregated vascular risk factors (VRFs) are associated with functional dependence and to what extent carotid at...
  18. Association between lipid profile and depressive symptoms among Chinese older people: mediation by cardiovascular diseases?

    International Journal of Behavioral Medicine 21(4):590 (2014) PMID 24136399

    The potential mediating effect of cardiovascular diseases (CVDs) (e.g., ischemic heart disease and stroke) on the association between abnormal serum lipids and late-life depressive symptoms has not been investigated. We aimed to examine the associations between serum lipids and elevated depressi...
  19. Behavioral medicine in China.

    International Journal of Behavioral Medicine 21(4):571 (2014) PMID 24898631

  20. Trends in incidence of hypertension in Chinese adults, 1991-2009: the China Health and Nutrition Survey.

    International Journal of Cardiology 175(1):96 (2014) PMID 24833472 PMCID PMC4105139

    Previous studies have shown an upward trend in the prevalence of hypertension, but data on trend of incidence of hypertension are lacking. We seek to investigate the trends in incidence of hypertension and control of incident hypertension among Chinese adults during 1991-1997 and 2004-2009. With...