1. MRI pattern in asymptomatic natalizumab-associated PML.

    Journal of Neurology, Neurosurgery & Psychiatry 86(7):793 (2015) PMID 25205744

    To investigate the MRI manifestation pattern of asymptomatic natalizumab-associated progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis (MS). 18 patients with MS with natalizumab-associated PML lesions on MRI were included. In 6 patients, the PML lesions were ide...
  2. PML in a patient without severe lymphocytopenia receiving dimethyl fumarate.

    New England Journal of Medicine 372(15):1474 (2015) PMID 25853764

    Progressive multifocal leukoencephalopathy developed in a 64-year-old woman who was treated with compounded dimethyl fumarate for psoriasis. Lymphocytopenia in this patient was not as severe as in other patients with PML receiving fumaric acid esters.
  3. Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature.

    Journal of Neurology 262(1):65 (2015) PMID 25297924

    Granule cell neuronopathy (GCN) is a rare JC virus (JCV)-related disease in immunocompromised patients, characterized by lytic infection of the cerebellar granule cell layer. To enable early diagnosis and intervention, we identify features of GCN and describe possible aspects of disease heteroge...
  4. Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature.

    Journal of Neurology 262(1):65 (2015) PMID 25297924

    Granule cell neuronopathy (GCN) is a rare JC virus (JCV)-related disease in immunocompromised patients, characterized by lytic infection of the cerebellar granule cell layer. To enable early diagnosis and intervention, we identify features of GCN and describe possible aspects of disease heteroge...
  5. Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature.

    Journal of Neurology 262(1):65 (2015) PMID 25297924

    Granule cell neuronopathy (GCN) is a rare JC virus (JCV)-related disease in immunocompromised patients, characterized by lytic infection of the cerebellar granule cell layer. To enable early diagnosis and intervention, we identify features of GCN and describe possible aspects of disease heteroge...
  6. Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?

    Journal of Neurology 261(6):1139 (2014) PMID 24705790

    The diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis patients in an asymptomatic stage is crucial since it is associated with better clinical outcome measures. Current diagnostic criteria on PML diagnosis in asymptomatic patients require ...
  7. Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?

    Journal of Neurology 261(6):1139 (2014) PMID 24705790

    The diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis patients in an asymptomatic stage is crucial since it is associated with better clinical outcome measures. Current diagnostic criteria on PML diagnosis in asymptomatic patients require ...
  8. Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?

    Journal of Neurology 261(6):1139 (2014) PMID 24705790

    The diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis patients in an asymptomatic stage is crucial since it is associated with better clinical outcome measures. Current diagnostic criteria on PML diagnosis in asymptomatic patients require ...
  9. Case reports of PML in patients treated for psoriasis.

    New England Journal of Medicine 369(11):1081 (2013) PMID 24040654

  10. Case reports of PML in patients treated for psoriasis.

    New England Journal of Medicine 369(11):1081 (2013) PMID 24040654

  11. Author response.

    Neurology 81(4):403 (2013) PMID 24044116

  12. Author response.

    Neurology 81(4):403 (2013) PMID 24044116

  13. What went wrong? The flawed concept of cerebrospinal venous insufficiency.

    Journal of Cerebral Blood Flow and Metabolism 33(5):657 (2013) PMID 23443168 PMCID PMC3652697

    In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the central nervous system is associated with multiple sclerosis (MS), coining the term of chronic cerebrospinal venous insufficiency ('CCSVI'). The diagnosis of 'CCSVI' is based on sonographic criteria, which he f...
  14. What went wrong? The flawed concept of cerebrospinal venous insufficiency.

    Journal of Cerebral Blood Flow and Metabolism 33(5):657 (2013) PMID 23443168 PMCID PMC3652697

    In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the central nervous system is associated with multiple sclerosis (MS), coining the term of chronic cerebrospinal venous insufficiency ('CCSVI'). The diagnosis of 'CCSVI' is based on sonographic criteria, which he f...
  15. PML in a patient treated with dimethyl fumarate from a compounding pharmacy.

    New England Journal of Medicine 368(17):1658 (2013) PMID 23614604

  16. PML in a patient treated with dimethyl fumarate from a compounding pharmacy.

    New England Journal of Medicine 368(17):1658 (2013) PMID 23614604

  17. Tumefactive multiple sclerosis lesions under fingolimod treatment.

    Neurology 79(19):2000 (2012) PMID 23035065

  18. Tumefactive multiple sclerosis lesions under fingolimod treatment.

    Neurology 79(19):2000 (2012) PMID 23035065

  19. Challenges in multi-plex and mono-plex platforms for the discovery of inflammatory profiles in neurodegenerative diseases.

    Methods 56(4):508 (2012) PMID 22465283

    Pro and anti-inflammatory cytokines are involved in disease onset and pathophysiology of multiple sclerosis, Alzheimer's disease and Parkinson's disease. It is likely that panels of multiple cytokines provide a good reflection of disease status and can be used as biological markers in body fluid...
  20. Challenges in multi-plex and mono-plex platforms for the discovery of inflammatory profiles in neurodegenerative diseases

    Methods 56(4):508 (2012)

    Pro and anti-inflammatory cytokines are involved in disease onset and pathophysiology of multiple sclerosis, Alzheimer’s disease and Parkinson’s disease. It is likely that panels of multiple cytokines provide a good reflection of disease status and can be used as biological markers in ...