1. Cross-talk and regulatory interactions between the essential response regulator RpaB and cyanobacterial circadian clock output.

    PNAS 112(7):2198 (2015) PMID 25653337

    The response regulator RpaB (regulator of phycobilisome associated B), part of an essential two-component system conserved in cyanobacteria that responds to multiple environmental signals, has recently been implicated in the control of cell dimensions and of circadian rhythms of gene expression ...
  2. Cross-talk and regulatory interactions between the essential response regulator RpaB and cyanobacterial circadian clock output.

    PNAS 112(7):2198 (2015) PMID 25653337 PMCID PMC4343135

    The response regulator RpaB (regulator of phycobilisome associated B), part of an essential two-component system conserved in cyanobacteria that responds to multiple environmental signals, has recently been implicated in the control of cell dimensions and of circadian rhythms of gene expression ...
  3. Cross-talk and regulatory interactions between the essential response regulator RpaB and cyanobacterial circadian clock output.

    PNAS 112(7):2198 (2015) PMID 25653337 PMCID PMC4343135

    The response regulator RpaB (regulator of phycobilisome associated B), part of an essential two-component system conserved in cyanobacteria that responds to multiple environmental signals, has recently been implicated in the control of cell dimensions and of circadian rhythms of gene expression ...
  4. PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

    PNAS 111(23):E2423 (2014) PMID 24912181 PMCID PMC4060718

    To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of...
  5. PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

    PNAS 111(23):E2423 (2014) PMID 24912181 PMCID PMC4060718

    To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of...
  6. PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

    PNAS 111(23):E2423 (2014) PMID 24912181 PMCID PMC4060718

    To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of...
  7. PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

    PNAS 111(23):E2423 (2014) PMID 24912181 PMCID PMC4060718

    To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of...
  8. PipX, the coactivator of NtcA, is a global regulator in cyanobacteria.

    PNAS 111(23):E2423 (2014) PMID 24912181 PMCID PMC4060718

    To modulate the expression of genes involved in nitrogen assimilation, the cyanobacterial PII-interacting protein X (PipX) interacts with the global transcriptional regulator NtcA and the signal transduction protein PII, a protein found in all three domains of life as an integrator of signals of...
  9. Negative control of cell size in the cyanobacteriumSynechococcus elongatusPCC 7942 by the essential response regulator RpaB

    FEBS Letters 587(5):504 (2013)

    Highlights ► S. elongatus strains with either constitutively increased or decreased expression of the essential rpaB gene are viable. ► The intracellular levels of RpaB affect cell size. ► Phosphorylated and non-phosphorylated RpaB play different cellular roles.
  10. Negative control of cell size in the cyanobacterium Synechococcus elongatus PCC 7942 by the essential response regulator RpaB.

    FEBS Letters 587(5):504 (2013) PMID 23340342

    The essential NblS-RpaB pathway for photosynthesis regulation and acclimatization to a variety of environmental conditions is the most conserved two-component system in cyanobacteria. To get insights into the RpaB implication in cell homeostasis we investigated the phenotypic impact of altering ...
  11. Negative control of cell size in the cyanobacterium Synechococcus elongatus PCC 7942 by the essential response regulator RpaB

    FEBS Letters 587(5):504 (2013) PMID 23340342

    Highlights ► S. elongatus strains with either constitutively increased or decreased expression of the essential rpaB gene are viable. ► The intracellular levels of RpaB affect cell size. ► Phosphorylated and non-phosphorylated RpaB play different cellular roles.
  12. In vivo features of signal transduction by the essential response regulator RpaB from Synechococcus elongatus PCC 7942.

    Microbiology 158(Pt 5):1229 (2012) PMID 22322959

    The NblS-RpaB signalling pathway, the most conserved two-component system in cyanobacteria, regulates photosynthesis and acclimatization to a variety of environmental conditions and is involved in negative regulation of high-light-induced genes. However, relevant regulatory details of the NblS-R...
  13. Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96.

    Biochimica et Biophysica Acta 1819(5):382 (2012) PMID 22306661

    Cyanobacteria respond to environmental stress conditions by adjusting their photosynthesis machinery. In Synechococcus sp. PCC 7942, phycobilisome degradation and other acclimation responses after nutrient or high light stress require activation by the phosphorylation-independent response regula...
  14. Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96

    Biochimica et Biophysica Acta (BBA) - Gene Regu... 1819(5):382 (2012) PMID 22306661

    Cyanobacteria respond to environmental stress conditions by adjusting their photosynthesis machinery. In Synechococcus sp. PCC 7942, phycobilisome degradation and other acclimation responses after nutrient or high light stress require activation by the phosphorylation-independent respo...
  15. Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96

    Biochimica et Biophysica Acta (BBA) - Gene Regu... 1819(5):382 (2012)

    Cyanobacteria respond to environmental stress conditions by adjusting their photosynthesis machinery. In Synechococcus sp. PCC 7942, phycobilisome degradation and other acclimation responses after nutrient or high light stress require activation by the phosphorylation-independent respo...
  16. Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96

    Biochimica et Biophysica Acta (BBA) - Gene Regu... 1819(5):382 (2012) PMID 22306661

    Cyanobacteria respond to environmental stress conditions by adjusting their photosynthesis machinery. In Synechococcus sp. PCC 7942, phycobilisome degradation and other acclimation responses after nutrient or high light stress require activation by the phosphorylation-independent respo...
  17. In vivo features of signal transduction by the essential response regulator RpaB from Synechococcus elongatus PCC 7942.

    Microbiology 158(Pt 5):1229 (2012) PMID 22322959

    The NblS-RpaB signalling pathway, the most conserved two-component system in cyanobacteria, regulates photosynthesis and acclimatization to a variety of environmental conditions and is involved in negative regulation of high-light-induced genes. However, relevant regulatory details of the NblS-R...
  18. Mutational analysis of the cyanobacterial nitrogen regulator PipX.

    PLoS ONE 7(4):e35845 (2012) PMID 22558239 PMCID PMC3340408

    PipX provides a functional link between the cyanobacterial global transcriptional regulator NtcA and the signal transduction protein P(II), a protein found in all three domains of life as integrators of signals of the nitrogen and carbon balance. PipX, which is toxic in the absence of P(II), can...
  19. Mutational analysis of the cyanobacterial nitrogen regulator PipX.

    PLoS ONE 7(4):e35845 (2012) PMID 22558239 PMCID PMC3340408

    PipX provides a functional link between the cyanobacterial global transcriptional regulator NtcA and the signal transduction protein P(II), a protein found in all three domains of life as integrators of signals of the nitrogen and carbon balance. PipX, which is toxic in the absence of P(II), can...
  20. The nitrogen interaction network in Synechococcus WH5701, a cyanobacterium with two PipX and two P(II)-like proteins.

    Microbiology 157(Pt 4):1220 (2011) PMID 21183574

    Nitrogen regulation involves the formation of different types of protein complexes between signal transducers and their transcriptional or metabolic targets. In oxygenic phototrophs, the signal integrator P(II) activates the enzyme N-acetyl-l-glutamate kinase (NAGK) by complex formation. P(II) a...