1. A small deletion in C9orf72 hides a proportion of expansion carriers in FTLD.

    Neurobiology of Aging 36(3):1601.e1 (2015) PMID 25595499

    Frontotemporal lobar degeneration is a highly familial disease and the most common known genetic cause is the repeat expansion mutation in the gene C9orf72. We have identified 2 brothers with an expansion mutation in C9orf72 using Southern blotting that is undetectable using repeat-primed polyme...
  2. Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.

    Neurobiology of Aging 36(3):1603.e1 (2015) PMID 25435337

    We have measured plasma progranulin and interleukin-6 in 230 patients with frontotemporal lobar degeneration (FTLD), 104 patients with Alzheimer's disease, and 161 control subjects. We have replicated previous findings of decreased levels of progranulin protein in FTLD because of mutations in GR...
  3. A small deletion in C9orf72 hides a proportion of expansion carriers in FTLD.

    Neurobiology of Aging 36(3):1601.e1 (2015) PMID 25595499

    Frontotemporal lobar degeneration is a highly familial disease and the most common known genetic cause is the repeat expansion mutation in the gene C9orf72. We have identified 2 brothers with an expansion mutation in C9orf72 using Southern blotting that is undetectable using repeat-primed polyme...
  4. Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.

    Neurobiology of Aging 36(3):1603.e1 (2015) PMID 25435337

    We have measured plasma progranulin and interleukin-6 in 230 patients with frontotemporal lobar degeneration (FTLD), 104 patients with Alzheimer's disease, and 161 control subjects. We have replicated previous findings of decreased levels of progranulin protein in FTLD because of mutations in GR...
  5. Single-molecule imaging at high fluorophore concentrations by local activation of dye.

    Biophysical Journal 108(4):949 (2015) PMID 25692599 PMCID PMC4336379

    Single-molecule fluorescence microscopy is a powerful tool for observing biomolecular interactions with high spatial and temporal resolution. Detecting fluorescent signals from individual labeled proteins above high levels of background fluorescence remains challenging, however. For this reason,...
  6. C9ORF72 in dementia with Lewy bodies.

    Journal of Neurology, Neurosurgery & Psychiatry 85(12):1435 (2014) PMID 24648039

  7. C9ORF72 in Dementia with Lewy bodies.

    Journal of Neurology, Neurosurgery & Psychiatry 85(12):1435 (2014) PMID 24648039

  8. A tool to aid talking about dementia and dying – Development and evaluation

    Collegian: Journal of the Royal College of Nurs... 21(4):337 (2014)

    Background Health professionals often avoid talking about death and dying with patients and relatives, and this avoidance is compounded in cases of dementia by lack of knowledge of trajectory and prognosis. Unfortunately, this impacts on care, with many terminally ill dementi...
  9. C9ORF72 in Dementia with Lewy bodies.

    Journal of Neurology, Neurosurgery & Psychiatry 85(12):1435 (2014) PMID 24648039

  10. Salt impregnated desiccant matrices for ‘open’ thermochemical energy storage—Selection, synthesis and characterisation of candidate materials

    Energy and Buildings 84:412 (2014)

    • A list of materials is provided for ‘open’ thermochemical energy storage (TES). • Characterisation of materials provided their hygrothermal and porous properties...
  11. Opportunities to Improve the Utilisation of Granulated Coals for Blast furnace Injection

    Fuel (2014)

    • Blending coals improved the burnout of low volatile content semi anthracitic coals. • Granulated samples showed a fragmentation effect in a drop tube furnace. ...
  12. Who knows, who cares? Dementia knowledge among nurses, care workers, and family members of people living with dementia.

    Journal of Palliative Care 30(3):158 (2014) PMID 25265739

    The number of people with dementia is increasing rapidly worldwide. Commensurate with population ageing, the use of nursing homes in Australia (known as residential aged care facilities) for individuals with dementia is growing. As a terminal condition, dementia is best managed by instituting a ...
  13. A systematic review of cognitive behavioral therapy for depression in Veterans.

    Military Medicine 179(9):942 (2014) PMID 25181709

    Research conducted in the civilian population demonstrates that cognitive-behavioral therapies are effective for depression, but some evidence suggests that Veterans' treatment response may differ from civilians. This review examined cognitive-behavioral treatment (CBT) for depression in Veteran...
  14. Guideline for referral of patients with suspected lung cancer by family physicians and other primary care providers.

    Canadian Family Physician 60(8):711 (2014) PMID 25122814 PMCID PMC4131959

    The aim of this guideline is to assist FPs and other primary care providers with recognizing features that should raise their suspicions about the presence of lung cancer in their patients. Committee members were selected from among the regional primary care leads from the Cancer Care Ontario Pr...
  15. Systematic review of guidelines for the management of suspected lung cancer in primary care.

    Canadian Family Physician 60(8):e395 (2014) PMID 25122830 PMCID PMC4131976

    To systematically review the literature and provide an update and integration of existing peer-reviewed guidelines with recent systematic reviews and with primary studies related to the early recognition and management of lung cancer in primary care. MEDLINE and EMBASE were searched for relevant...
  16. Learning opportunities in a residential aged care facility: the role of supported placements for first-year nursing students.

    Journal of Nursing Education 53(7):410 (2014) PMID 24972402

    The residential aged care sector is reportedly a less attractive career choice for nursing students than other sectors. Research shows that students are often fearful of working with residents with dementia when they are inadequately supported on clinical placements by aged care staff. Thirty fi...
  17. Family involvement in decision making for people with dementia in residential aged care: a systematic review of quantitative literature.

    International Journal Of Evidence Based Healthcare 12(2):64 (2014) PMID 24945958

    Ensuring older adults' involvement in their care is accepted as good practice and is vital, particularly for people with dementia, whose care and treatment needs change considerably over the course of the illness. However, involving family members in decision making on people's behalf is still p...
  18. A mobile-phone-based breath carbon monoxide meter to detect cigarette smoking.

    Nicotine & Tobacco Research 16(6):766 (2014) PMID 24470633 PMCID PMC4031569

    Mobile phones hold considerable promise for delivering evidence-based smoking cessation interventions that require frequent and objective assessment of smoking status via breath carbon monoxide (Breath CO) measurement. However, there are currently no commercially available mobile-phone-based Bre...
  19. A mobile-phone-based breath carbon monoxide meter to detect cigarette smoking.

    Nicotine & Tobacco Research 16(6):766 (2014) PMID 24470633 PMCID PMC4031569

    Mobile phones hold considerable promise for delivering evidence-based smoking cessation interventions that require frequent and objective assessment of smoking status via breath carbon monoxide (Breath CO) measurement. However, there are currently no commercially available mobile-phone-based Bre...
  20. A mobile-phone-based breath carbon monoxide meter to detect cigarette smoking.

    Nicotine & Tobacco Research 16(6):766 (2014) PMID 24470633 PMCID PMC4031569

    Mobile phones hold considerable promise for delivering evidence-based smoking cessation interventions that require frequent and objective assessment of smoking status via breath carbon monoxide (Breath CO) measurement. However, there are currently no commercially available mobile-phone-based Bre...