1. Effect of aerobic exercise training dose on liver fat and visceral adiposity.

    Journal of Hepatology 63(1):174 (2015) PMID 25863524

    Aerobic exercise reduces liver fat and visceral adipose tissue (VAT). However, there is limited data from randomized trials to inform exercise programming recommendations. This study examined the efficacy of commonly prescribed exercise doses for reducing liver fat and VAT using a randomized pla...
  2. Postprandial metabolism in adults with Prader-Willi syndrome.

    Obesity 23(6):1159 (2015) PMID 25958986

    Individuals with Prader-Willi syndrome (PWS) are commonly restricted to 60-75% of height-appropriate calorie intake because they rapidly become obese on a normal diet. This study measured changes in energy expenditure, glucose and lipid homeostasis, and metabolic flexibility in response to a mea...
  3. The effect of a high-egg diet on cardiovascular risk factors in people with type 2 diabetes: the Diabetes and Egg (DIABEGG) study-a 3-mo randomized controlled trial.

    American Journal of Clinical Nutrition 101(4):705 (2015) PMID 25833969

    Previously published research that examined the effects of high egg consumption in people with type 2 diabetes (T2D) produced conflicting results leading to recommendations to limit egg intake. However, people with T2D may benefit from egg consumption because eggs are a nutritious and convenient...
  4. Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.

    PLoS ONE 10(7):e0133362 (2015) PMID 26207898 PMCID PMC4514813

    The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct action of MIC-1/GDF15 on feeding centres in t...
  5. Do people with morbid obesity have deep psychological problems? Apparently not

    Obesity Research & Clinical Practice 8:61 (2014)

  6. Technological support to enhance weight loss and weight loss maintenance among obese adults: A pilot randomised controlled trial

    Obesity Research & Clinical Practice 8:122 (2014)

  7. Muscle strength is reduced by an 8-week weight reducing diet in overweight and obese adults with pre-diabetes: A sub-study of the PREVIEW Study Australia

    Obesity Research & Clinical Practice 8:121 (2014)

  8. Do ketogenic diets really suppress appetite? A systematic review and meta-analysis

    Obesity Research & Clinical Practice 8:36 (2014)

  9. Daily cold exposure – A therapy to stimulate beige fat or a recipe for diabesity in mice?

    Obesity Research & Clinical Practice 8:59 (2014)

  10. How low do you need to go? Carbohydrate restriction for appetite suppression during low energy diets in overweight and obese adults: A sub-study of the PREVIEW Study Australia

    Obesity Research & Clinical Practice 8:23 (2014)

  11. Macrophage inhibitory cytokine 1 (MIC-1/GDF15), a novel regulator of body weight and appetite and a potential therapeutic for obesity

    Obesity Research & Clinical Practice 8:105 (2014)

  12. Glycyrrhizic acid can attenuate metabolic deviations caused by a high-sucrose diet without causing water retention in male Sprague-Dawley rats.

    Nutrients 6(11):4856 (2014) PMID 25375630 PMCID PMC4245567

    Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its potential therapeutic use is marred by edema caused by inhibition of renal 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2). We assessed whether 100 mg/kg per day GA administered orally could promote metabolic ben...
  13. Glycyrrhizic acid can attenuate metabolic deviations caused by a high-sucrose diet without causing water retention in male Sprague-Dawley rats.

    Nutrients 6(11):4856 (2014) PMID 25375630 PMCID PMC4245567

    Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its potential therapeutic use is marred by edema caused by inhibition of renal 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2). We assessed whether 100 mg/kg per day GA administered orally could promote metabolic ben...
  14. Double deletion of orexigenic neuropeptide Y and dynorphin results in paradoxical obesity in mice.

    Neuropeptides 48(3):143 (2014) PMID 24680736

    Orexigenic neuropeptide Y (NPY) and dynorphin (DYN) regulate energy homeostasis. Single NPY or dynorphin deletion reduces food intake or increases fat loss. Future developments of obesity therapeutics involve targeting multiple pathways. We hypothesised that NPY and dynorphin regulate energy hom...
  15. Double deletion of orexigenic neuropeptide Y and dynorphin results in paradoxical obesity in mice

    Neuropeptides 48(3):143 (2014)

    Objective Orexigenic neuropeptide Y (NPY) and dynorphin (DYN) regulate energy homeostasis. Single NPY or dynorphin deletion reduces food intake or increases fat loss. Future developments of obesity therapeutics involve targeting multiple pathways. We hypothesised that NPY and...
  16. Double deletion of orexigenic neuropeptide Y and dynorphin results in paradoxical obesity in mice.

    Neuropeptides 48(3):143 (2014) PMID 24680736

    Orexigenic neuropeptide Y (NPY) and dynorphin (DYN) regulate energy homeostasis. Single NPY or dynorphin deletion reduces food intake or increases fat loss. Future developments of obesity therapeutics involve targeting multiple pathways. We hypothesised that NPY and dynorphin regulate energy hom...
  17. Pancreatic Polypeptide Controls Energy Homeostasis viaNpy6rSignaling in the Suprachiasmatic Nucleus in Mice

    Cell Metabolism 19(1):58 (2014)

    Y-receptors control energy homeostasis, but the role of Npy6 receptors (Npy6r) is largely unknown. Young Npy6r-deficient (Npy6r−/−) mice have reduced body weight, lean mass, and adiposity, while older and high-fat-fed Npy6r−/− mice have low lean mass with increased adiposity. Npy6r−/− ...
  18. Pancreatic Polypeptide Controls Energy Homeostasis viaNpy6rSignaling in the Suprachiasmatic Nucleus in Mice

    Cell Metabolism 19(1):58 (2014) PMID 24411939

    Y-receptors control energy homeostasis, but the role of Npy6 receptors (Npy6r) is largely unknown. Young Npy6r-deficient (Npy6r−/−) mice have reduced body weight, lean mass, and adiposity, while older and high-fat-fed Npy6r−/− mice have low lean mass with increased adiposity. Npy6r−/− ...
  19. Pancreatic polypeptide controls energy homeostasis via Npy6r signaling in the suprachiasmatic nucleus in mice.

    Cell Metabolism 19(1):58 (2014) PMID 24411939

    Y-receptors control energy homeostasis, but the role of Npy6 receptors (Npy6r) is largely unknown. Young Npy6r-deficient (Npy6r(-/-)) mice have reduced body weight, lean mass, and adiposity, while older and high-fat-fed Npy6r(-/-) mice have low lean mass with increased adiposity. Npy6r(-/-) mice...
  20. Continuous exercise but not high intensity interval training improves fat distribution in overweight adults.

    Journal of Obesity 2014:834865 (2014) PMID 24669314 PMCID PMC3942093

    The purpose of this study was to assess the effect of high intensity interval training (HIIT) versus continuous aerobic exercise training (CONT) or placebo (PLA) on body composition by randomized controlled design. Work capacity and body composition (dual-energy X-ray absorptiometry) were measur...